Hub : Traits : BMI without tail : ← : →

chr1:267,847,096-270,504,995

Trait: BMI without tail

Best TWAS P = 1.35e-22 · Best GWAS P= 2.60e-23 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Ces2c	gene expression	Ces2c	0.12	46	0.07	4.0e-08	-6.04	1.53e-09	0.11	FALSE
Adipose	Dennd10	gene expression	Dennd10	0.04	1	0.04	4.7e-05	7.92	2.40e-15	0.02	FALSE
Adipose	Grk5	gene expression	Grk5	0.19	1480	0.24	3.9e-26	7.83	4.75e-15	0	FALSE
Adipose	LOC120100068	gene expression	LOC120100068	0.03	1	0.02	4.3e-03	7.04	1.99e-12	0.03	FALSE
Adipose	Prdx3	gene expression	Prdx3	0.19	1	0.24	1.6e-26	7.48	7.53e-14	0	FALSE
Adipose	Sfxn4	gene expression	Sfxn4	0.02	1	0.02	2.5e-03	8.77	1.85e-18	0.03	FALSE
Adipose	Zfp933l1	gene expression	Zfp933l1	0.05	19	0.06	4.1e-07	-7.7	1.33e-14	0	FALSE
Adipose	Emx2os	intron excision ratio	chr1_268557371_268612388	0.03	1	0.01	1.7e-02	6.84	7.96e-12	0.03	FALSE
Adipose	Emx2os	mRNA stability	Emx2os	0.19	16	0.15	1.9e-16	-7.33	2.37e-13	0	FALSE
Adipose	LOC120100068	mRNA stability	LOC120100068	0.31	2143	0.18	1.8e-19	8.88	6.74e-19	0	FALSE
BLA	Ces2c	gene expression	Ces2c	0.25	1	0.17	2.6e-09	-7.98	1.41e-15	0.77	FALSE
BLA	Emx2os	gene expression	Emx2os	0.38	1	0.21	3.7e-11	6.81	9.61e-12	0	FALSE
BLA	Rab11fip2	gene expression	Rab11fip2	0.1	2416	0.04	2.2e-03	-8.5	1.82e-17	0.21	FALSE
BLA	Sfxn4	gene expression	Sfxn4	0.07	1	0.02	3.4e-02	-9.41	4.94e-21	0.04	FALSE
BLA	Cacul1	isoform ratio	NM_001014248.2	0.09	1822	0.02	3.1e-02	5.48	4.24e-08	0.09	FALSE
BLA	Emx2os	mRNA stability	Emx2os	0.3	26	0.12	9.6e-07	8.08	6.52e-16	0.02	FALSE
BLA	LOC120100068	mRNA stability	LOC120100068	0.37	1	0.11	3.2e-06	-7.96	1.74e-15	0.03	FALSE
BLA	Rab11fip2	mRNA stability	Rab11fip2	0.09	1	0.06	3.9e-04	8.49	2.12e-17	0.04	FALSE
Brain	Ces2c	gene expression	Ces2c	0.23	1	0.27	2.7e-25	-7.93	2.28e-15	0.68	FALSE
Brain	Emx2os	gene expression	Emx2os	0.37	2255	0.3	1.8e-28	-6.11	1.01e-09	0	FALSE
Brain	LOC134485266	gene expression	LOC134485266	0.35	21	0.29	3.4e-27	5.77	7.97e-09	0	FALSE
Brain	Nanos1	gene expression	Nanos1	0.11	1686	0.09	1.3e-08	-7.52	5.51e-14	0.55	FALSE
Brain	Rab11fip2	gene expression	Rab11fip2	0.1	1	0.06	3.8e-06	7.84	4.60e-15	0.02	FALSE
Brain	Sfxn4	gene expression	Sfxn4	0.07	1433	0.08	4.5e-08	7.18	6.73e-13	0.09	FALSE
Brain	Zfp933l1	gene expression	Zfp933l1	0.05	2	0.06	5.3e-06	8.13	4.22e-16	0.04	FALSE
Brain	Cacul1	isoform ratio	NM_001014248.2	0.11	36	0.1	1.6e-09	-8.18	2.83e-16	0.87	FALSE
Brain	Cacul1	isoform ratio	NM_001416001.1	0.1	1	0.08	3.5e-08	9.48	2.47e-21	0.32	FALSE
Brain	Cacul1	intron excision ratio	chr1_269663603_269672274	0.11	1	0.08	4.3e-08	-9.48	2.47e-21	0.32	FALSE
Brain	LOC134485267	intron excision ratio	chr1_269851730_269854168	0.02	1	0.03	1.9e-03	-8.39	4.86e-17	0.03	FALSE
Brain	Emx2os	mRNA stability	Emx2os	0.26	84	0.17	1.8e-15	6.26	3.75e-10	0	FALSE
Brain	Grk5	mRNA stability	Grk5	0.03	1480	0.02	2.3e-03	-8.27	1.35e-16	0.11	FALSE
Brain	LOC120100068	mRNA stability	LOC120100068	0.5	9	0.2	1.0e-18	7.73	1.06e-14	0	FALSE
Eye	Emx2os	mRNA stability	Emx2os	0.71	45	0.2	5.4e-04	-6.68	2.36e-11	0.14	FALSE
IC	Ces2c	gene expression	Ces2c	0.26	1	0.22	1.9e-09	-8	1.24e-15	0.79	FALSE
IC	Emx2os	gene expression	Emx2os	0.57	1	0.39	1.1e-17	6.94	4.05e-12	0	FALSE
IC	Grk5	gene expression	Grk5	0.12	1	0.07	7.4e-04	-9.47	2.81e-21	0.05	FALSE
IC	Sfxn4	gene expression	Sfxn4	0.18	95	0.13	3.1e-06	-5.43	5.73e-08	0.01	FALSE
IC	Cacul1	isoform ratio	NM_001014248.2	0.1	5	0.04	8.5e-03	9.49	2.24e-21	0.52	FALSE
IC	Cacul1	isoform ratio	NM_001416001.1	0.1	1	0.06	1.1e-03	8.29	1.16e-16	0.04	FALSE
IL	Ces2c	gene expression	Ces2c	0.38	1	0.3	5.3e-08	-7.98	1.41e-15	0.57	FALSE
IL	Sfxn4	mRNA stability	Sfxn4	0.51	1	0.22	4.5e-06	-7.95	1.88e-15	0.05	FALSE
LHb	Ces2c	gene expression	Ces2c	0.26	73	0.21	1.2e-05	-7.31	2.68e-13	0.56	FALSE
LHb	Rab11fip2	gene expression	Rab11fip2	0.24	1	0.1	2.3e-03	7.84	4.60e-15	0.05	FALSE
Liver	Nanos1	gene expression	Nanos1	0.08	1	0.06	5.6e-07	7.58	3.33e-14	0	FALSE
Liver	Cacul1	isoform ratio	NM_001014248.2	0.03	1822	0.01	7.0e-03	7.72	1.19e-14	0.33	FALSE
Liver	Ces2c	mRNA stability	Ces2c	0.02	1	0.01	7.1e-03	7.96	1.79e-15	0.04	FALSE
Liver	Grk5	mRNA stability	Grk5	0.03	1480	0.01	3.6e-02	-8.03	9.44e-16	0.21	FALSE
NAcc	Ces2c	gene expression	Ces2c	0.15	105	0.21	1.0e-31	-7.74	1.00e-14	0.77	FALSE
NAcc	Emx2os	gene expression	Emx2os	0.38	17	0.27	2.4e-40	-6.06	1.40e-09	0	FALSE
NAcc	LOC134485266	gene expression	LOC134485266	0.2	1	0.12	2.3e-18	-6.53	6.45e-11	0	FALSE
NAcc	Prlhr	gene expression	Prlhr	0.16	116	0.15	5.0e-22	-8.75	2.17e-18	0.93	FALSE
NAcc	Rab11fip2	gene expression	Rab11fip2	0.02	1	0.02	1.6e-03	8.52	1.55e-17	0.02	FALSE
NAcc	Sfxn4	gene expression	Sfxn4	0.05	16	0.06	1.5e-09	9.64	5.65e-22	0.13	TRUE
NAcc	Cacul1	isoform ratio	NM_001014248.2	0.16	1	0.05	9.7e-08	-9.55	1.32e-21	0.47	FALSE
NAcc	LOC134485267	intron excision ratio	chr1_269851730_269854168	0.07	1717	0.04	5.0e-07	6.74	1.59e-11	0.85	TRUE
NAcc	Emx2os	mRNA stability	Emx2os	0.07	1	0.07	1.6e-10	6.87	6.38e-12	0	FALSE
NAcc	Grk5	mRNA stability	Grk5	0.04	1	0.05	9.3e-08	6.23	4.67e-10	0	FALSE
OFC	Grk5	alternative TSS	XM_039088827.2	0.1	1	0.13	7.1e-04	-8.42	3.82e-17	0.05	FALSE
OFC	Ces2c	gene expression	Ces2c	0.29	1	0.3	5.7e-08	-7.99	1.31e-15	0.53	FALSE
OFC	LOC134485266	gene expression	LOC134485266	0.26	2202	0.11	1.2e-03	6.89	5.40e-12	0.13	FALSE
OFC	Rab11fip2	gene expression	Rab11fip2	0.27	165	0.21	9.4e-06	9.22	3.07e-20	0.34	FALSE
OFC	Sfxn4	gene expression	Sfxn4	0.47	39	0.28	2.9e-07	6.99	2.71e-12	0.03	FALSE
OFC	Rab11fip2	mRNA stability	Rab11fip2	0.27	21	0.18	5.8e-05	8.84	9.46e-19	0.42	FALSE
PL	Cacul1	alternative TSS	XM_063270019.1	0.04	1822	0.01	7.7e-03	-5.57	2.62e-08	0.09	FALSE
PL	Ces2c	gene expression	Ces2c	0.64	32	0.37	6.7e-43	7.94	2.06e-15	0.75	FALSE
PL	Emx2os	gene expression	Emx2os	0.43	2	0.31	5.6e-35	-6.69	2.16e-11	0	FALSE
PL	Grk5	gene expression	Grk5	0.02	82	0.01	1.3e-02	-5.85	4.98e-09	0.06	FALSE
PL	LOC134485266	gene expression	LOC134485266	0.19	51	0.11	1.8e-12	5.37	7.70e-08	0	FALSE
PL	Nanos1	gene expression	Nanos1	0.11	1686	0.06	1.9e-07	-6.16	7.33e-10	0.27	FALSE
PL	Sfxn4	gene expression	Sfxn4	0.1	1433	0.1	4.4e-11	8.56	1.16e-17	0.03	FALSE
PL	Zfp933l1	gene expression	Zfp933l1	0.05	74	0.03	2.3e-04	-7.02	2.18e-12	0.06	FALSE
PL	Cacul1	isoform ratio	NM_001014248.2	0.02	1822	0.01	1.3e-02	9.78	1.35e-22	0.75	TRUE
PL	Cacul1	isoform ratio	XM_063270019.1	0.04	1822	0.02	1.4e-03	-6.18	6.38e-10	0.12	FALSE
PL	Emx2os	mRNA stability	Emx2os	0.22	5	0.12	2.8e-13	-6.67	2.48e-11	0	FALSE
pVTA	Ces2c	gene expression	Ces2c	0.34	1	0.35	2.5e-29	-7.94	2.04e-15	0.7	FALSE
pVTA	Emx2os	gene expression	Emx2os	0.25	1	0.12	1.0e-09	7.02	2.14e-12	0	TRUE
pVTA	Nanos1	gene expression	Nanos1	0.12	103	0.05	1.4e-04	5.85	5.05e-09	0.05	TRUE
pVTA	Sfxn4	gene expression	Sfxn4	0.06	1433	0.04	3.2e-04	8.85	8.42e-19	0.44	FALSE
pVTA	Grk5	mRNA stability	Grk5	0.06	1480	0.05	6.5e-05	-8.91	5.34e-19	0.18	FALSE
RMTg	Fam204a	gene expression	Fam204a	0.19	2296	0.01	1.4e-01	5.43	5.73e-08	0.13	FALSE
RMTg	Sfxn4	intron excision ratio	chr1_269977345_269977444	0.17	118	0.05	2.3e-02	9.51	1.97e-21	0.46	FALSE