Best TWAS P=1.646725e-07 · Best GWAS P=5.599518e-08 conditioned to 1
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NAcc | RGD1311703 | gene expression | ENSRNOG00000053659 | 0.10 | 0.08 | enet | 13 | 0.08 | 9.4e-07 | -4.9 | 5.2 | 2.5e-07 | -0.77 | 0.43 | 0.57 | FALSE |
2 | PL | Xylt1 | gene expression | ENSRNOG00000056658 | 0.04 | 0.05 | top1 | 1 | 0.05 | 1.9e-04 | -5.2 | -5.2 | 1.6e-07 | 0.93 | 0.09 | 0.08 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.