chr1:179,280,032-183,039,706

Trait: BMI without tail

Best TWAS P = 1.19e-08 · Best GWAS P= 9.41e-09 conditioned to 1.72e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose LOC134485167 gene expression LOC134485167 0.06 2244 0 9.8e-02 5.51 3.62e-08 0.36 FALSE
Adipose Plekha7 gene expression Plekha7 0.34 1041 0.06 8.0e-07 5.29 1.24e-07 0.47 FALSE
BLA Rps15a gene expression Rps15a 0.14 2737 0.1 6.7e-06 -5.49 4.08e-08 0.46 FALSE
Brain Plekha7 alternative TSS XM_063279498.1 0.03 1 0.01 1.6e-02 5.3 1.18e-07 0.04 FALSE
Brain LOC120099912 gene expression LOC120099912 0.14 1 0.13 6.8e-12 5.3 1.18e-07 0.76 FALSE
Brain Smg1 intron excision ratio chr1_181954419_181977476 0.05 1 0.01 2.2e-02 -5.26 1.45e-07 0.04 FALSE
IC Rps15a gene expression Rps15a 0.14 7 0.06 1.8e-03 -5.51 3.56e-08 0.15 FALSE
IL Rps15a gene expression Rps15a 0.16 2737 0 2.8e-01 -5.7 1.19e-08 0.28 TRUE
NAcc Tmc7 intron excision ratio chr1_182317521_182320753 0.05 14 0.05 9.6e-08 5.32 1.06e-07 0.57 FALSE
OFC Xylt1 gene expression Xylt1 0.23 35 0.06 1.3e-02 5.44 5.19e-08 0.21 FALSE
pVTA Tmc7 gene expression Tmc7 0.22 31 0.23 1.3e-18 5.3 1.17e-07 0.57 FALSE
pVTA Syt17 isoform ratio XM_017588770.3 0.04 1 0.03 1.1e-03 -5.54 3.10e-08 0.14 FALSE
pVTA Rps15a intron excision ratio chr1_181860280_181861108 0.1 15 0.08 5.1e-07 5.32 1.04e-07 0.62 FALSE
pVTA Syt17 intron excision ratio chr1_182191400_182195689 0.05 2706 0.02 4.5e-03 -5.37 7.82e-08 0.44 FALSE
pVTA Syt17 intron excision ratio chr1_182191405_182195689 0.05 2706 0.04 7.5e-04 5.3 1.14e-07 0.53 FALSE