Best TWAS P=3.410695e-08 · Best GWAS P=2.574895e-07 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | BLA | RGD1359508 | gene expression | ENSRNOG00000038330 | 0.12 | 0.04 | blup | 931 | 0.06 | 5.3e-04 | -4.5 | 5.4 | 8.1e-08 | -0.95 | 0.41 | 0.51 | FALSE |
| 2 | BLA | RGD1359508 | mRNA stability | ENSRNOG00000038330 | 0.09 | -0.01 | lasso | 3 | 0.00 | 7.3e-01 | -5.0 | -5.5 | 3.4e-08 | 0.96 | 0.20 | 0.28 | TRUE |
| 3 | Brain | RGD1359508 | gene expression | ENSRNOG00000038330 | 0.13 | 0.15 | blup | 931 | 0.16 | 1.5e-14 | -4.8 | 5.4 | 5.3e-08 | -0.92 | 0.39 | 0.61 | FALSE |
| 4 | Brain | RGD1359508 | intron excision ratio | chr2:124783582:124783672 | 0.03 | 0.02 | blup | 931 | 0.02 | 5.8e-03 | -4.7 | 5.2 | 2.3e-07 | -0.95 | 0.39 | 0.38 | FALSE |
| 5 | NAcc | RGD1359508 | gene expression | ENSRNOG00000038330 | 0.23 | 0.14 | enet | 37 | 0.15 | 5.9e-11 | -5.1 | 5.4 | 8.5e-08 | -0.97 | 0.40 | 0.60 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.