Hub : Traits : Bone: periosteal estimation : ← : →

chr10:89,561,948-96,071,622

Trait: Bone: periosteal estimation

Best TWAS P=6.11e-09 · Best GWAS P=2.01e-08 conditioned to NaN

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Ddx5	alternative polyA	ENSRNOT00000048490	0.04	1	0.04	4.8e-05	5.17	2.36e-07	0.35	FALSE
Adipose	Ddx5	alternative polyA	ENSRNOT00000098583	0.04	15	0.03	1.7e-04	-5.13	2.86e-07	0.57	FALSE
Adipose	Ddx5	alternative polyA	ENSRNOT00000048490	0.04	1	0.04	1.5e-05	5.17	2.36e-07	0.53	FALSE
Adipose	Ddx5	alternative polyA	ENSRNOT00000098583	0.04	1	0.04	2.6e-05	-5.17	2.36e-07	0.48	FALSE
Adipose	Bptf	alternative polyA	ENSRNOT00000104873	0.02	1815	0.02	1.4e-03	-5.2	2.00e-07	0.55	FALSE
Adipose	Bptf	alternative polyA	ENSRNOT00000104176	0.03	1815	0.03	5.5e-04	5.35	8.69e-08	0.57	FALSE
Adipose	Bptf	alternative polyA	ENSRNOT00000104873	0.03	1815	0.03	5.7e-04	-5.36	8.47e-08	0.57	FALSE
Adipose	Taco1	gene expression	ENSRNOG00000008405	0.1	1	0.07	7.1e-08	-5.46	4.75e-08	0.81	FALSE
Adipose	Ddx42	gene expression	ENSRNOG00000009474	0.11	2012	0.06	3.8e-07	-5.14	2.76e-07	0.66	FALSE
Adipose	Smarcd2	gene expression	ENSRNOG00000010557	0.03	2046	0.03	4.9e-04	5.24	1.61e-07	0.51	FALSE
Adipose	Scn4a	gene expression	ENSRNOG00000012134	0.35	27	0.33	5.9e-38	5.22	1.75e-07	0.79	FALSE
Adipose	Smurf2	gene expression	ENSRNOG00000014623	0.17	30	0.18	7.0e-20	-5.2	2.02e-07	0.88	FALSE
Adipose	Cep112	gene expression	ENSRNOG00000024557	0.19	2145	0.15	2.3e-16	5.12	3.11e-07	0.03	FALSE
Adipose	ENSRNOG00000043295	gene expression	ENSRNOG00000043295	0.34	225	0.42	2.7e-50	-5.4	6.83e-08	0.81	FALSE
Adipose	Tanc2	gene expression	ENSRNOG00000052840	0.2	25	0.2	5.0e-22	5.35	8.84e-08	0.75	FALSE
Adipose	ENSRNOG00000063680	gene expression	ENSRNOG00000063680	0.11	1	0.08	2.0e-09	-5.42	6.01e-08	0.78	FALSE
Adipose	ENSRNOG00000067362	gene expression	ENSRNOG00000067362	0.12	26	0.06	8.5e-07	-5.17	2.32e-07	0.07	FALSE
Adipose	ENSRNOG00000069533	gene expression	ENSRNOG00000069533	0.03	1918	0.02	9.2e-04	-5.37	8.08e-08	0.41	FALSE
Adipose	Dcaf7	isoform ratio	ENSRNOT00000063858	0.02	1	0.01	1.3e-02	5.35	9.04e-08	0.04	FALSE
Adipose	Dcaf7	isoform ratio	ENSRNOT00000104554	0.02	5	0.01	6.9e-03	-5.52	3.31e-08	0.62	TRUE
Adipose	Icam2	intron excision ratio	chr10:91313731:91315221	0.07	17	0.08	7.9e-09	-5.31	1.10e-07	0.71	FALSE
Adipose	Psmd12	mRNA stability	ENSRNOG00000003117	0.08	11	0.07	9.3e-09	5.25	1.49e-07	0.34	FALSE
Adipose	Taco1	mRNA stability	ENSRNOG00000008405	0.12	77	0.09	9.2e-10	-5.15	2.61e-07	0.72	FALSE
Adipose	Scn4a	mRNA stability	ENSRNOG00000012134	0.03	2100	0.02	9.0e-04	-5.26	1.44e-07	0.52	FALSE
Adipose	Kpna2	mRNA stability	ENSRNOG00000015329	0.03	2020	0.01	2.7e-02	5.44	5.18e-08	0.4	FALSE
Adipose	ENSRNOG00000043295	mRNA stability	ENSRNOG00000043295	0.08	116	0.07	2.2e-08	-5.46	4.75e-08	0.74	FALSE
BLA	Psmd12	alternative polyA	ENSRNOT00000004283	0.18	1	0.17	2.2e-09	-5.3	1.18e-07	0.43	FALSE
BLA	Psmd12	alternative polyA	ENSRNOT00000105451	0.18	1	0.17	1.5e-09	5.3	1.18e-07	0.43	FALSE
BLA	Psmd12	alternative TSS	ENSRNOT00000004283	0.25	62	0.3	2.1e-16	5.54	3.05e-08	0.43	FALSE
BLA	Psmd12	alternative TSS	ENSRNOT00000112540	0.24	13	0.29	4.7e-16	-5.46	4.88e-08	0.44	FALSE
BLA	Psmd12	alternative TSS	ENSRNOT00000004283	0.21	74	0.26	2.0e-14	5.58	2.46e-08	0.42	FALSE
BLA	Psmd12	alternative TSS	ENSRNOT00000112540	0.22	19	0.29	8.4e-16	-5.44	5.24e-08	0.44	FALSE
BLA	Helz	gene expression	ENSRNOG00000003213	0.2	1	0.26	4.9e-14	-5.26	1.45e-07	0.35	FALSE
BLA	Cacng5	gene expression	ENSRNOG00000003288	0.28	36	0.1	3.8e-06	-5.16	2.42e-07	0	FALSE
BLA	Fam20a	gene expression	ENSRNOG00000003969	0.21	171	0.16	7.8e-09	-5.31	1.11e-07	0.58	FALSE
BLA	Ccdc47	gene expression	ENSRNOG00000009006	0.07	2024	0.04	4.1e-03	5.29	1.21e-07	0.44	FALSE
BLA	ENSRNOG00000043295	gene expression	ENSRNOG00000043295	0.52	27	0.4	6.9e-23	-5.13	2.93e-07	0.55	FALSE
BLA	Prkar1a	gene expression	ENSRNOG00000049876	0.12	2933	0.06	4.5e-04	5.24	1.59e-07	0.59	FALSE
BLA	AABR07030630.1	gene expression	ENSRNOG00000052124	0.08	2263	0.06	3.0e-04	-5.27	1.34e-07	0.23	FALSE
BLA	Prr29	gene expression	ENSRNOG00000060193	0.07	2112	0.04	2.4e-03	-5.1	3.48e-07	0.4	FALSE
BLA	ENSRNOG00000063680	gene expression	ENSRNOG00000063680	0.37	64	0.3	2.2e-16	-5.56	2.70e-08	0.78	FALSE
BLA	ENSRNOG00000067362	gene expression	ENSRNOG00000067362	0.36	1	0.19	1.3e-10	-5.48	4.24e-08	0.61	FALSE
BLA	ENSRNOG00000069533	gene expression	ENSRNOG00000069533	0.18	106	0.21	1.6e-11	-5.39	6.88e-08	0.39	FALSE
BLA	Taco1	mRNA stability	ENSRNOG00000008405	0.15	1869	0.14	1.1e-07	-5.21	1.84e-07	0.71	FALSE
Brain	Psmd12	alternative polyA	ENSRNOT00000004283	0.13	1	0.16	2.1e-14	-5.15	2.56e-07	0.27	FALSE
Brain	Psmd12	alternative polyA	ENSRNOT00000105451	0.13	1	0.16	1.6e-14	5.15	2.56e-07	0.27	FALSE
Brain	Ddx5	alternative polyA	ENSRNOT00000048490	0.05	1	0.05	1.2e-05	5.26	1.44e-07	0.9	FALSE
Brain	Psmd12	alternative TSS	ENSRNOT00000004283	0.63	1	0.39	1.6e-38	5.3	1.18e-07	0.43	FALSE
Brain	Psmd12	alternative TSS	ENSRNOT00000112540	0.58	1	0.4	3.4e-39	-5.3	1.18e-07	0.43	FALSE
Brain	Psmd12	alternative TSS	ENSRNOT00000004283	0.61	1	0.37	1.8e-35	5.3	1.18e-07	0.43	FALSE
Brain	Psmd12	alternative TSS	ENSRNOT00000112540	0.57	1	0.41	1.3e-40	-5.3	1.18e-07	0.43	FALSE
Brain	Cacng4	gene expression	ENSRNOG00000003262	0.21	177	0.19	1.0e-17	5.34	9.22e-08	0.64	FALSE
Brain	Wipi1	gene expression	ENSRNOG00000003827	0.74	2914	0.52	1.3e-56	5.34	9.52e-08	0.6	FALSE
Brain	Kcnh6	gene expression	ENSRNOG00000008078	0.05	1981	0.03	2.2e-03	-5.24	1.63e-07	0.72	FALSE
Brain	Ccdc47	gene expression	ENSRNOG00000009006	0.14	1	0.1	8.0e-10	5.32	1.06e-07	0.68	FALSE
Brain	ENSRNOG00000043295	gene expression	ENSRNOG00000043295	0.41	71	0.5	1.1e-52	-5.26	1.45e-07	0.48	FALSE
Brain	Bptf	gene expression	ENSRNOG00000047296	0.06	1	0.05	4.0e-05	-5.11	3.16e-07	0.25	FALSE
Brain	ENSRNOG00000063680	gene expression	ENSRNOG00000063680	0.24	1	0.28	1.2e-25	-5.37	8.09e-08	0.72	FALSE
Brain	ENSRNOG00000067362	gene expression	ENSRNOG00000067362	0.08	23	0.1	7.1e-10	-5.24	1.59e-07	0.36	FALSE
Brain	ENSRNOG00000067823	gene expression	ENSRNOG00000067823	0.14	26	0.15	1.0e-13	-5.47	4.59e-08	0.39	FALSE
Brain	Ddx5	isoform ratio	ENSRNOT00000048490	0.04	2	0.04	9.8e-05	5.14	2.73e-07	0.69	FALSE
Brain	Strada	intron excision ratio	chr10:91114968:91117516	0.03	1	0.02	2.4e-03	-5.27	1.39e-07	0.05	FALSE
Brain	Psmd12	mRNA stability	ENSRNOG00000003117	0.21	1	0.26	2.6e-24	5.33	9.80e-08	0.47	FALSE
Brain	Map2k6	mRNA stability	ENSRNOG00000004437	0.18	35	0.22	5.2e-20	5.62	1.90e-08	0.45	FALSE
Brain	Taco1	mRNA stability	ENSRNOG00000008405	0.16	19	0.23	6.3e-21	-5.46	4.76e-08	0.8	FALSE
Brain	Bptf	mRNA stability	ENSRNOG00000047296	0.07	1835	0.07	2.2e-07	5.33	9.93e-08	0.74	FALSE
IL	Strada	mRNA stability	ENSRNOG00000008637	0.32	1	0.24	2.0e-06	5.37	8.09e-08	0.33	FALSE
LHb	Scn4a	gene expression	ENSRNOG00000012134	0.54	184	0.2	1.6e-05	5.47	4.45e-08	0.75	FALSE
LHb	ENSRNOG00000063680	gene expression	ENSRNOG00000063680	0.47	1856	0.27	3.7e-07	-5.26	1.41e-07	0.64	FALSE
LHb	Psmd12	mRNA stability	ENSRNOG00000003117	0.25	1	0.06	1.7e-02	5.27	1.35e-07	0.05	FALSE
LHb	Taco1	mRNA stability	ENSRNOG00000008405	0.24	1	0.18	4.2e-05	-5.42	5.88e-08	0.18	FALSE
Liver	Psmd12	alternative polyA	ENSRNOT00000004283	0.07	1798	0.1	6.6e-11	-5.39	7.16e-08	0.55	FALSE
Liver	Psmd12	alternative polyA	ENSRNOT00000105451	0.07	1798	0.1	1.2e-10	5.36	8.34e-08	0.55	FALSE
Liver	Cacng4	gene expression	ENSRNOG00000003262	0.14	2023	0.15	1.7e-16	5.3	1.14e-07	0.38	FALSE
Liver	Prkca	gene expression	ENSRNOG00000003491	0.65	52	0.26	2.0e-28	5.25	1.52e-07	0.43	FALSE
Liver	Rgs9	gene expression	ENSRNOG00000003800	0.16	2491	0.12	6.0e-13	-5.3	1.13e-07	0.46	FALSE
Liver	Cep112	gene expression	ENSRNOG00000024557	0.04	2145	0.02	1.3e-03	5.26	1.45e-07	0.34	FALSE
Liver	ENSRNOG00000063680	gene expression	ENSRNOG00000063680	0.1	1852	0.11	9.6e-12	-5.14	2.76e-07	0.69	FALSE
Liver	ENSRNOG00000069533	gene expression	ENSRNOG00000069533	0.03	1918	0.03	5.6e-04	-5.36	8.54e-08	0.39	FALSE
Liver	Icam2	intron excision ratio	chr10:91311489:91313031	0.12	1	0.09	1.0e-09	5.29	1.25e-07	0.67	FALSE
Liver	Icam2	intron excision ratio	chr10:91313731:91315221	0.29	23	0.27	1.9e-30	-5.16	2.52e-07	0.59	FALSE
Liver	Psmd12	mRNA stability	ENSRNOG00000003117	0.09	1	0.14	4.9e-15	5.16	2.45e-07	0.27	FALSE
Liver	Ccdc47	mRNA stability	ENSRNOG00000009006	0.05	2013	0.02	1.2e-03	5.12	3.00e-07	0.35	FALSE
Liver	Map3k3	mRNA stability	ENSRNOG00000061424	0.03	1859	0.01	7.0e-03	-5.45	5.00e-08	0.58	FALSE
NAcc	Ddx5	alternative polyA	ENSRNOT00000048490	0.06	1	0.03	1.3e-03	5.29	1.22e-07	0.4	FALSE
NAcc	Ddx5	alternative polyA	ENSRNOT00000098583	0.06	1	0.04	5.3e-04	-5.29	1.22e-07	0.59	FALSE
NAcc	Psmd12	gene expression	ENSRNOG00000003117	0.06	1	0.08	1.5e-06	-5.14	2.78e-07	0.19	FALSE
NAcc	Cacng4	gene expression	ENSRNOG00000003262	0.12	2299	0.12	2.9e-09	5.22	1.80e-07	0.61	FALSE
NAcc	Apoh	gene expression	ENSRNOG00000003566	0.21	2363	0.21	2.8e-15	5.13	2.95e-07	0.01	TRUE
NAcc	Wipi1	gene expression	ENSRNOG00000003827	0.62	21	0.48	1.6e-39	5.31	1.07e-07	0.6	FALSE
NAcc	Mrc2	gene expression	ENSRNOG00000006548	0.15	126	0.09	6.3e-07	5.21	1.87e-07	0.38	FALSE
NAcc	Ccdc47	gene expression	ENSRNOG00000009006	0.04	2014	0.04	1.3e-03	5.22	1.80e-07	0.62	FALSE
NAcc	ENSRNOG00000043295	gene expression	ENSRNOG00000043295	0.55	266	0.52	2.9e-44	-5.36	8.55e-08	0.49	FALSE
NAcc	AABR07030630.1	gene expression	ENSRNOG00000052124	0.11	2261	0.1	1.4e-07	-5.16	2.45e-07	0.02	FALSE
NAcc	Ace	gene expression	ENSRNOG00000062101	0.1	1	0.06	3.7e-05	-5.27	1.34e-07	0.44	FALSE
NAcc	ENSRNOG00000063680	gene expression	ENSRNOG00000063680	0.34	4	0.23	3.6e-17	-5.51	3.66e-08	0.69	FALSE
NAcc	Ddx42	isoform ratio	ENSRNOT00000013046	0.13	1	0.1	5.2e-08	-5.33	9.88e-08	0.69	FALSE
NAcc	Ddx42	isoform ratio	ENSRNOT00000112384	0.13	24	0.12	3.0e-09	5.39	7.12e-08	0.72	FALSE
NAcc	Taco1	mRNA stability	ENSRNOG00000008405	0.17	1	0.14	9.4e-11	-5.27	1.34e-07	0.62	FALSE
NAcc	Dcaf7	mRNA stability	ENSRNOG00000042245	0.17	1919	0.1	3.5e-08	5.23	1.72e-07	0.76	FALSE
NAcc	ENSRNOG00000043295	mRNA stability	ENSRNOG00000043295	0.06	12	0.05	1.6e-04	-5.11	3.15e-07	0.63	FALSE
NAcc	Map3k3	mRNA stability	ENSRNOG00000061424	0.06	4	0.04	4.0e-04	-5.3	1.15e-07	0.36	TRUE
OFC	Prr29	gene expression	ENSRNOG00000060193	0.24	1	0.09	3.5e-03	-5.42	6.01e-08	0.07	FALSE
OFC	Ace	gene expression	ENSRNOG00000062101	0.33	1	0.15	2.4e-04	-5.27	1.34e-07	0.14	FALSE
PL	Psmd12	alternative polyA	ENSRNOT00000004283	0.08	1991	0.09	2.0e-07	-5.16	2.53e-07	0.42	FALSE
PL	Psmd12	alternative polyA	ENSRNOT00000105451	0.08	1991	0.09	2.4e-07	5.2	1.98e-07	0.43	FALSE
PL	Psmd12	alternative TSS	ENSRNOT00000004283	0.28	1	0.22	1.5e-16	5.33	9.81e-08	0.47	FALSE
PL	Psmd12	alternative TSS	ENSRNOT00000112540	0.3	1	0.21	1.4e-15	-5.33	9.81e-08	0.47	FALSE
PL	Psmd12	alternative TSS	ENSRNOT00000004283	0.22	1	0.2	4.1e-15	5.33	9.81e-08	0.47	FALSE
PL	Psmd12	alternative TSS	ENSRNOT00000112540	0.32	1	0.21	1.4e-15	-5.33	9.81e-08	0.47	FALSE
PL	Prkar1a	alternative TSS	ENSRNOT00000095989	0.04	2927	0.04	1.0e-03	5.39	7.03e-08	0.38	FALSE
PL	Wipi1	gene expression	ENSRNOG00000003827	0.44	23	0.38	6.5e-30	5.23	1.69e-07	0.61	FALSE
PL	Fam20a	gene expression	ENSRNOG00000003969	0.23	2975	0.21	7.2e-16	-5.12	2.98e-07	0.38	FALSE
PL	Ccdc47	gene expression	ENSRNOG00000009006	0.08	2014	0.03	1.3e-03	5.22	1.80e-07	0.22	FALSE
PL	ENSRNOG00000043295	gene expression	ENSRNOG00000043295	0.37	178	0.43	7.5e-36	-5.31	1.09e-07	0.52	FALSE
PL	AABR07030630.1	gene expression	ENSRNOG00000052124	0.08	2	0.09	3.2e-07	-5.81	6.11e-09	0.08	TRUE
PL	ENSRNOG00000063680	gene expression	ENSRNOG00000063680	0.35	11	0.35	4.9e-28	-5.13	2.88e-07	0.64	FALSE
PL	ENSRNOG00000067362	gene expression	ENSRNOG00000067362	0.16	1	0.23	2.1e-17	-5.14	2.78e-07	0.21	FALSE
PL	ENSRNOG00000069533	gene expression	ENSRNOG00000069533	0.23	3	0.26	6.9e-20	-5.29	1.22e-07	0.32	FALSE
PL	Psmd12	mRNA stability	ENSRNOG00000003117	0.13	3	0.18	8.3e-14	5.43	5.70e-08	0.39	TRUE
PL	Map2k6	mRNA stability	ENSRNOG00000004437	0.13	62	0.14	6.7e-11	5.1	3.38e-07	0.37	FALSE
PL	Dcaf7	mRNA stability	ENSRNOG00000042245	0.16	1	0.12	4.7e-09	5.47	4.48e-08	0.81	FALSE
PL	Bptf	mRNA stability	ENSRNOG00000047296	0.05	1	0.05	8.1e-05	5.14	2.68e-07	0.11	FALSE