Hub : Traits : Bone: periosteal estimation : ← : →

chr10:89,723,294-95,835,187

Trait: Bone: periosteal estimation

Best TWAS P=3.03e-09 · Best GWAS P=2.01e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Cep112	alternative polyA	XM_039085647.1	0.03	2155	0.02	1.6e-03	5.38	7.28e-08	0.44	FALSE
Adipose	Cep112	alternative polyA	XM_039085653.1	0.07	2155	0.07	2.3e-08	-5.26	1.40e-07	0.46	FALSE
Adipose	Arsg	alternative TSS	XM_008768369.2	0.04	2838	0.02	2.6e-03	-5.29	1.21e-07	0.41	FALSE
Adipose	Ccdc47	alternative TSS	NM_001013974.1	0.04	2063	0.02	5.5e-03	5.32	1.02e-07	0.65	FALSE
Adipose	Ccdc47	alternative TSS	XM_039086169.1	0.04	2063	0.02	3.0e-03	-5.37	7.73e-08	0.67	TRUE
Adipose	C10h17orf58	gene expression	C10h17orf58	0.33	51	0.42	7.2e-51	-5.3	1.14e-07	0.82	FALSE
Adipose	Dcaf7	gene expression	Dcaf7	0.11	143	0.09	4.6e-10	5.2	1.94e-07	0.75	FALSE
Adipose	Ddx42	gene expression	Ddx42	0.12	7	0.06	1.1e-07	-5.18	2.18e-07	0.66	FALSE
Adipose	Kcnh6	gene expression	Kcnh6	0.04	34	0.02	3.8e-03	5.28	1.31e-07	0.1	TRUE
Adipose	Psmd12	gene expression	Psmd12	0.13	1800	0.11	7.0e-12	-5.28	1.31e-07	0.57	FALSE
Adipose	Scn4a	gene expression	Scn4a	0.33	25	0.33	2.8e-37	5.31	1.07e-07	0.79	FALSE
Adipose	Smurf2	gene expression	Smurf2	0.25	1	0.24	8.8e-27	5.34	9.42e-08	0.9	FALSE
Adipose	Tanc2	gene expression	Tanc2	0.19	1	0.19	4.3e-21	-5.32	1.06e-07	0.7	FALSE
Adipose	Cep112	isoform ratio	XM_039085653.1	0.06	2155	0.05	2.3e-06	-5.23	1.67e-07	0.39	FALSE
Adipose	Cep112	isoform ratio	XR_005489759.1	0.04	2155	0.02	1.2e-03	-5.19	2.08e-07	0.34	FALSE
Adipose	Helz	isoform ratio	XM_006247565.4	0.02	1771	0.01	3.6e-02	-5.49	3.94e-08	0.39	FALSE
Adipose	Psmd12	isoform ratio	NM_001005875.1	0.06	1	0.07	3.6e-08	-5.28	1.32e-07	0.4	FALSE
Adipose	Psmd12	isoform ratio	XM_039085636.1	0.06	1	0.07	3.1e-08	5.28	1.32e-07	0.4	FALSE
Adipose	Psmd12	mRNA stability	Psmd12	0.05	1	0.05	1.9e-06	-5.27	1.35e-07	0.38	FALSE
BLA	Helz	alternative polyA	XM_039085638.1	0.09	2037	0.03	6.7e-03	-5.64	1.66e-08	0.42	FALSE
BLA	Psmd12	alternative polyA	NM_001005875.1	0.15	1	0.23	2.2e-12	-5.29	1.21e-07	0.42	FALSE
BLA	Psmd12	alternative polyA	XM_039085636.1	0.16	1	0.24	3.9e-13	5.29	1.21e-07	0.42	FALSE
BLA	C10h17orf58	gene expression	C10h17orf58	0.52	406	0.42	1.9e-24	5.17	2.28e-07	0.56	FALSE
BLA	Cacng4	gene expression	Cacng4	0.13	1	0.08	4.1e-05	-5.3	1.16e-07	0.1	FALSE
BLA	Fam20a	gene expression	Fam20a	0.25	2993	0.14	3.8e-08	-5.21	1.92e-07	0.59	FALSE
BLA	Kpna2	gene expression	Kpna2	0.08	1	0.07	1.6e-04	5.27	1.35e-07	0.19	FALSE
BLA	LOC120095203	gene expression	LOC120095203	0.27	2596	0.27	6.7e-15	5.18	2.16e-07	0.41	TRUE
BLA	Helz	isoform ratio	XM_006247562.4	0.07	2037	0.03	1.6e-02	-5.22	1.77e-07	0.28	FALSE
BLA	Psmd12	isoform ratio	NM_001005875.1	0.18	1	0.2	8.0e-11	-5.29	1.21e-07	0.42	FALSE
BLA	Psmd12	isoform ratio	XM_039085636.1	0.21	1	0.2	3.9e-11	5.29	1.21e-07	0.42	FALSE
Brain	LOC108352150	alternative polyA	XR_001840306.2	0.02	2305	0.02	4.4e-03	5.44	5.35e-08	0.47	FALSE
Brain	LOC108352150	alternative polyA	XR_005490490.1	0.02	2305	0.02	4.4e-03	-5.44	5.36e-08	0.47	FALSE
Brain	Psmd12	alternative polyA	NM_001005875.1	0.15	28	0.19	4.5e-17	5.52	3.30e-08	0.42	FALSE
Brain	Psmd12	alternative polyA	XM_039085636.1	0.15	30	0.18	9.7e-17	-5.54	2.96e-08	0.43	FALSE
Brain	Psmd12	alternative TSS	NM_001005875.1	0.04	2001	0.02	1.0e-02	-5.2	2.02e-07	0.37	FALSE
Brain	Psmd12	alternative TSS	XM_039085636.1	0.04	2001	0.02	7.4e-03	5.19	2.12e-07	0.38	TRUE
Brain	Ace	gene expression	Ace	0.1	10	0.1	7.9e-10	-5.18	2.24e-07	0.74	FALSE
Brain	C10h17orf58	gene expression	C10h17orf58	0.42	25	0.52	1.4e-56	-5.19	2.09e-07	0.48	FALSE
Brain	Wipi1	gene expression	Wipi1	0.74	2923	0.61	2.4e-71	5.39	6.93e-08	0.59	FALSE
Brain	C10h17orf58	isoform ratio	XM_039086648.1	0.04	2008	0.01	5.4e-02	5.42	5.81e-08	0.55	FALSE
Brain	Psmd12	isoform ratio	NM_001005875.1	0.09	1	0.11	4.1e-10	-5.23	1.68e-07	0.35	FALSE
Brain	Psmd12	isoform ratio	XM_039085636.1	0.09	1	0.1	7.0e-10	5.23	1.68e-07	0.35	FALSE
Brain	LOC120095188	intron excision ratio	chr10_90474854_90527932	0.04	2540	0.04	2.8e-04	5.18	2.19e-07	0.44	FALSE
Brain	Taco1	mRNA stability	Taco1	0.14	37	0.18	1.0e-16	-5.47	4.60e-08	0.8	FALSE
Eye	Pitpnc1	isoform ratio	XM_039087431.1	0.38	210	0.18	1.1e-03	5.72	1.05e-08	0.31	FALSE
IL	Psmd12	alternative polyA	XM_039085636.1	0.14	8	0.07	7.8e-03	-5.47	4.47e-08	0.26	TRUE
IL	Cyb561	alternative TSS	XM_039086163.1	0.29	17	0.06	1.3e-02	-5.25	1.49e-07	0.33	TRUE
IL	C10h17orf58	gene expression	C10h17orf58	0.34	2008	0.25	1.3e-06	-5.38	7.36e-08	0.42	FALSE
IL	Helz	gene expression	Helz	0.21	104	0.15	1.7e-04	5.43	5.61e-08	0.29	FALSE
IL	Smurf2	gene expression	Smurf2	0.53	32	0.36	1.9e-09	5.28	1.33e-07	0.6	FALSE
IL	Axin2	isoform ratio	XM_039085704.1	0.18	2034	0.1	2.0e-03	-5.2	2.04e-07	0.24	FALSE
IL	Strada	mRNA stability	Strada	0.34	1	0.3	5.8e-08	-5.37	8.09e-08	0.4	FALSE
LHb	Prkca	gene expression	Prkca	0.18	1	0.16	1.2e-04	-5.29	1.22e-07	0.32	FALSE
LHb	Scn4a	gene expression	Scn4a	0.58	4	0.24	2.2e-06	5.45	5.10e-08	0.75	FALSE
LHb	Taco1	mRNA stability	Taco1	0.17	1	0.15	1.9e-04	5.42	5.88e-08	0.09	FALSE
Liver	LOC120095200	alternative polyA	XR_005490497.1	0.2	2144	0.17	9.9e-19	5.32	1.04e-07	0.41	FALSE
Liver	LOC120095200	alternative polyA	XR_005490496.1	0.21	164	0.22	7.6e-24	-5.29	1.21e-07	0.4	FALSE
Liver	Psmd12	alternative polyA	NM_001005875.1	0.09	1	0.14	3.9e-15	-5.34	9.32e-08	0.48	FALSE
Liver	Psmd12	alternative polyA	XM_039085636.1	0.09	1	0.14	6.8e-15	5.34	9.32e-08	0.48	FALSE
Liver	Rgs9	alternative polyA	NM_019224.2	0.06	4	0.04	2.2e-05	-5.93	3.03e-09	0.61	TRUE
Liver	Rgs9	alternative polyA	XM_039085765.1	0.06	2496	0.04	5.1e-05	5.57	2.58e-08	0.56	FALSE
Liver	Abca9	alternative TSS	XM_039087440.1	0.03	3128	0.01	9.4e-03	-5.21	1.88e-07	0.22	FALSE
Liver	Cacng4	gene expression	Cacng4	0.13	2030	0.15	1.8e-16	5.27	1.38e-07	0.38	FALSE
Liver	LOC120095197	gene expression	LOC120095197	0.11	26	0.09	2.0e-10	5.38	7.27e-08	0.25	TRUE
Liver	Icam2	isoform ratio	XM_006247627.4	0.05	1	0.04	3.7e-05	-5.37	8.09e-08	0.45	FALSE
Liver	Icam2	isoform ratio	XM_008768379.3	0.04	2147	0.02	3.6e-03	5.47	4.60e-08	0.7	FALSE
Liver	Nol11	isoform ratio	XR_005490485.1	0.04	1	0.03	4.4e-04	-5.49	4.07e-08	0.64	FALSE
Liver	Psmd12	isoform ratio	NM_001005875.1	0.06	1800	0.07	1.5e-08	5.23	1.68e-07	0.46	FALSE
Liver	Wipi1	intron excision ratio	chr10_94553836_94564588	0.06	2918	0.03	7.5e-04	-5.24	1.62e-07	0.44	FALSE
Liver	Map3k3	mRNA stability	Map3k3	0.03	1	0.02	2.8e-03	5.37	8.09e-08	0.06	FALSE
Liver	Psmd12	mRNA stability	Psmd12	0.02	1800	0.03	3.3e-04	5.41	6.21e-08	0.47	FALSE
Liver	Taco1	mRNA stability	Taco1	0.09	1897	0.11	6.0e-12	-5.35	8.64e-08	0.72	FALSE
NAcc	Psmd12	alternative polyA	NM_001005875.1	0.06	17	0.08	1.2e-09	5.17	2.28e-07	0.38	FALSE
NAcc	Psmd12	alternative polyA	XM_039085636.1	0.07	1	0.1	1.9e-11	5.26	1.41e-07	0.39	FALSE
NAcc	Ace	gene expression	Ace	0.09	1	0.08	1.1e-09	5.27	1.34e-07	0.59	FALSE
NAcc	C10h17orf58	gene expression	C10h17orf58	0.52	186	0.57	5.5e-80	5.28	1.32e-07	0.48	FALSE
NAcc	Cacng4	gene expression	Cacng4	0.14	1	0.15	4.5e-17	-5.56	2.76e-08	0.7	FALSE
NAcc	Ccdc47	gene expression	Ccdc47	0.04	2067	0.04	3.2e-05	5.51	3.66e-08	0.74	FALSE
NAcc	LOC108352143	gene expression	LOC108352143	0.05	3	0.06	6.0e-07	-5.28	1.29e-07	0.64	FALSE
NAcc	LOC108352150	gene expression	LOC108352150	0.07	40	0.05	3.2e-06	5.28	1.30e-07	0.63	FALSE
NAcc	Psmd12	gene expression	Psmd12	0.02	2001	0.02	2.3e-03	-5.26	1.47e-07	0.37	FALSE
NAcc	Tanc2	gene expression	Tanc2	0.23	1	0.12	1.5e-13	5.38	7.63e-08	0.76	FALSE
NAcc	Wipi1	gene expression	Wipi1	0.64	48	0.54	5.1e-74	5.25	1.51e-07	0.6	FALSE
NAcc	LOC108352150	isoform ratio	XR_005490490.1	0.04	48	0.03	3.7e-04	-5.79	7.21e-09	0.55	FALSE
NAcc	Psmd12	isoform ratio	NM_001005875.1	0.05	12	0.08	3.7e-09	5.61	1.99e-08	0.38	FALSE
NAcc	Psmd12	isoform ratio	XM_039085636.1	0.04	1	0.05	1.9e-06	5.3	1.18e-07	0.42	FALSE
NAcc	Cacng5	mRNA stability	Cacng5	0.03	2462	0.02	2.1e-03	-5.43	5.65e-08	0.54	FALSE
NAcc	Dcaf7	mRNA stability	Dcaf7	0.07	1	0.06	1.4e-07	-5.27	1.34e-07	0.6	FALSE
NAcc	Helz	mRNA stability	Helz	0.02	1	0.02	8.7e-04	5.29	1.24e-07	0.06	FALSE
NAcc	Limd2	mRNA stability	Limd2	0.02	1	0.01	1.4e-02	5.43	5.72e-08	0.06	FALSE
NAcc	Taco1	mRNA stability	Taco1	0.2	25	0.12	2.4e-13	5.35	9.00e-08	0.75	FALSE
OFC	Ace	gene expression	Ace	0.45	34	0.27	4.7e-07	-5.27	1.36e-07	0.63	FALSE
OFC	Strada	isoform ratio	NM_001415111.1	0.18	12	0.08	5.2e-03	5.45	5.15e-08	0.65	FALSE
PL	Psmd12	alternative polyA	NM_001005875.1	0.11	2001	0.17	6.4e-18	5.6	2.12e-08	0.41	FALSE
PL	Psmd12	alternative polyA	XM_039085636.1	0.11	2001	0.17	3.5e-18	-5.59	2.32e-08	0.39	FALSE
PL	Marchf10	alternative TSS	XM_017597337.2	0.03	2477	0.02	1.9e-03	5.41	6.27e-08	0.58	FALSE
PL	Ace	gene expression	Ace	0.18	24	0.28	9.8e-31	-5.19	2.08e-07	0.62	FALSE
PL	C10h17orf58	gene expression	C10h17orf58	0.43	97	0.51	1.1e-64	5.36	8.44e-08	0.48	FALSE
PL	Ccdc47	gene expression	Ccdc47	0.08	6	0.05	1.2e-06	5.32	1.04e-07	0.49	FALSE
PL	Helz	gene expression	Helz	0.37	50	0.43	8.9e-51	-5.21	1.85e-07	0.37	FALSE
PL	LOC108352151	gene expression	LOC108352151	0.12	1	0.13	1.5e-14	5.53	3.22e-08	0.68	FALSE
PL	Wipi1	gene expression	Wipi1	0.47	2923	0.42	1.4e-50	5.18	2.27e-07	0.6	FALSE
PL	C10h17orf58	isoform ratio	XM_039086648.1	0.03	24	0.03	5.8e-04	-5.33	1.01e-07	0.75	FALSE
PL	Psmd12	isoform ratio	NM_001005875.1	0.08	8	0.1	1.6e-11	5.3	1.15e-07	0.37	FALSE
PL	Psmd12	isoform ratio	XM_039085636.1	0.09	10	0.11	1.3e-11	-5.35	8.86e-08	0.34	FALSE
PL	Map3k3	intron excision ratio	chr10_91078047_91080296	0.03	1	0	9.5e-02	5.33	9.65e-08	0.05	FALSE
PL	Bptf	mRNA stability	Bptf	0.07	17	0.09	4.3e-10	5.27	1.40e-07	0.6	FALSE
PL	Cacng4	mRNA stability	Cacng4	0.06	1	0.06	1.1e-06	5.53	3.22e-08	0.64	FALSE
PL	Dcaf7	mRNA stability	Dcaf7	0.1	1	0.08	2.1e-09	-5.52	3.45e-08	0.84	FALSE
PL	Taco1	mRNA stability	Taco1	0.09	11	0.1	1.4e-10	-5.28	1.26e-07	0.76	FALSE
pVTA	Psmd12	alternative polyA	NM_001005875.1	0.17	1	0.13	3.5e-06	-5.3	1.18e-07	0.27	FALSE
pVTA	Cyb561	alternative TSS	XM_008768357.3	0.23	7	0.06	1.9e-03	5.28	1.29e-07	0.08	FALSE
pVTA	Prkca	mRNA stability	Prkca	0.2	191	0.03	2.2e-02	5.39	6.92e-08	0.37	TRUE