Hub : Traits : Left kidney weight : ← →

chr5:120,763,959-123,615,898

Trait: Left kidney weight

Best TWAS P=1.7576e-08 · Best GWAS P=4.336046e-07 conditioned to 0.4706649

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Hspb11	gene expression	ENSRNOG00000010241	0.22	0.08	enet	71	0.16	2.3e-17	3.6	5.3	1.4e-07	0.66	0.79	0.21	FALSE
2	Adipose	Ttc4	gene expression	ENSRNOG00000042467	0.05	0.02	blup	1500	0.02	2.1e-03	4.2	-5.6	1.8e-08	-0.82	0.34	0.48	TRUE
3	Adipose	Echdc2	mRNA stability	ENSRNOG00000029333	0.04	0.02	enet	41	0.02	1.4e-03	4.8	5.4	7.1e-08	0.91	0.42	0.51	FALSE
4	Brain	Yipf1	gene expression	ENSRNOG00000010512	0.08	0.04	blup	2073	0.05	1.1e-05	4.2	5.4	7.9e-08	0.73	0.96	0.03	FALSE
5	Brain	Acot11	mRNA stability	ENSRNOG00000007837	0.14	0.16	blup	1637	0.18	1.5e-16	4.6	-5.3	1.1e-07	-0.92	0.40	0.60	FALSE
6	LHb	Fam151a	gene expression	ENSRNOG00000007799	0.18	0.10	lasso	3	0.12	1.0e-03	4.8	-5.3	1.0e-07	-0.90	0.27	0.30	FALSE
7	LHb	Mroh7	gene expression	ENSRNOG00000058870	0.35	0.12	enet	10	0.17	8.1e-05	4.8	-5.5	3.1e-08	-0.75	0.32	0.45	FALSE
8	LHb	Acot11	mRNA stability	ENSRNOG00000007837	0.29	0.14	blup	1631	0.20	1.7e-05	3.6	-5.3	9.5e-08	-0.86	0.47	0.47	FALSE
9	NAcc	Glis1	gene expression	ENSRNOG00000000138	0.04	0.00	blup	2050	0.01	2.6e-02	4.6	-5.4	8.4e-08	-0.92	0.43	0.33	FALSE
10	NAcc	Fam151a	gene expression	ENSRNOG00000007799	0.11	0.03	blup	1464	0.07	3.7e-06	3.5	-5.6	2.7e-08	-0.81	0.47	0.53	FALSE
11	NAcc	Acot11	gene expression	ENSRNOG00000007837	0.07	0.01	blup	1635	0.03	4.9e-03	3.8	-5.3	1.3e-07	-0.76	0.59	0.23	FALSE
12	NAcc	Scp2	gene expression	ENSRNOG00000011413	0.12	0.05	blup	1723	0.07	1.0e-05	4.8	-5.1	2.6e-07	-0.99	0.45	0.55	FALSE
13	PL	Slc1a7	alternative polyA	ENSRNOT00000016557	0.05	0.00	blup	1926	0.01	6.9e-02	3.9	-5.1	2.6e-07	-0.91	0.41	0.29	FALSE
14	PL	Slc1a7	alternative polyA	ENSRNOT00000016557	0.06	0.02	blup	1926	0.03	2.9e-03	4.8	-5.3	1.4e-07	-0.99	0.45	0.47	FALSE
15	PL	Slc1a7	alternative polyA	ENSRNOT00000077808	0.06	0.02	blup	1926	0.03	2.8e-03	4.8	5.3	1.3e-07	0.99	0.45	0.47	FALSE
16	PL	Fam151a	mRNA stability	ENSRNOG00000007799	0.04	0.01	blup	1464	0.01	4.1e-02	4.6	-5.3	1.2e-07	-0.83	0.33	0.28	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.