Hub : Traits : Left kidney weight : ← : →

chr5:148,815,339-150,187,748

Trait: Left kidney weight

Best TWAS P=1.37e-09 · Best GWAS P=1.07e-09 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Eif4g3	alternative polyA	XM_039109676.1	0.38	808	0.02	2.4e-03	-5.52	3.39e-08	0.42	FALSE
Adipose	Ece1	alternative TSS	XM_006239275.4	0.02	1	0.01	2.0e-02	5.27	1.36e-07	0.03	FALSE
Adipose	Alpl	gene expression	Alpl	0.08	1001	0.12	2.5e-13	5.29	1.23e-07	0.42	FALSE
Adipose	Hspg2	gene expression	Hspg2	0.06	1	0.08	1.4e-09	-5.26	1.40e-07	0.34	FALSE
Adipose	Ece1	isoform ratio	XM_006239275.4	0.03	926	0.03	3.8e-04	-5.28	1.26e-07	0.49	FALSE
Adipose	Hspg2	isoform ratio	XM_017593852.2	0.27	1372	0.4	5.2e-47	-5.3	1.13e-07	0.41	FALSE
Adipose	Hspg2	isoform ratio	XM_039111304.1	0.26	70	0.38	6.0e-44	5.36	8.44e-08	0.43	FALSE
Adipose	Ece1	intron excision ratio	chr5_150126242_150133824	0.03	52	0.03	4.8e-04	5.28	1.31e-07	0.43	FALSE
Adipose	Ece1	intron excision ratio	chr5_150133272_150133824	0.03	52	0.03	6.7e-04	-5.28	1.31e-07	0.43	FALSE
Adipose	Hspg2	intron excision ratio	chr5_149716950_149718780	0.17	1372	0.23	1.2e-24	5.18	2.25e-07	0.45	FALSE
Adipose	Hspg2	intron excision ratio	chr5_149716950_149719207	0.27	1372	0.39	2.4e-46	-5.26	1.47e-07	0.41	FALSE
Adipose	Hspg2	intron excision ratio	chr5_149718830_149719207	0.23	32	0.33	5.0e-38	5.26	1.43e-07	0.4	FALSE
BLA	Ece1	gene expression	Ece1	0.13	926	0.09	9.9e-06	-5.29	1.20e-07	0.51	FALSE
BLA	Usp48	gene expression	Usp48	0.07	1	0.03	6.7e-03	-5.29	1.21e-07	0.04	FALSE
BLA	Rap1gap	mRNA stability	Rap1gap	0.04	1146	0.02	2.4e-02	-5.21	1.91e-07	0.35	FALSE
Brain	Eif4g3	alternative TSS	NM_001106693.1	0.09	808	0.07	1.8e-07	5.31	1.10e-07	0.56	FALSE
Brain	Eif4g3	alternative TSS	NM_001401860.1	0.1	1	0.1	4.0e-09	5.27	1.35e-07	0.54	FALSE
Brain	Eif4g3	alternative TSS	NM_001106693.1	0.08	808	0.07	2.6e-07	5.31	1.11e-07	0.56	FALSE
Brain	Eif4g3	alternative TSS	NM_001401860.1	0.1	2	0.09	8.8e-09	-5.27	1.35e-07	0.56	FALSE
Brain	Rap1gap	alternative TSS	XM_017593412.2	0.03	1	0.02	2.8e-03	6.06	1.37e-09	0.27	TRUE
Brain	Alpl	gene expression	Alpl	0.07	1	0.09	5.5e-09	-5.36	8.20e-08	0.46	FALSE
Brain	Rap1gap	intron excision ratio	chr5_149931941_149934662	0.02	1	0.01	2.3e-02	-5.6	2.10e-08	0.04	FALSE
Brain	Rap1gap	mRNA stability	Rap1gap	0.14	1146	0.22	4.3e-20	-5.29	1.20e-07	0.44	FALSE
Eye	Usp48	gene expression	Usp48	0.65	1263	0.13	5.5e-03	5.35	9.03e-08	0.36	FALSE
Eye	Usp48	mRNA stability	Usp48	0.5	1263	0.18	1.0e-03	-5.31	1.13e-07	0.32	FALSE
IL	Usp48	gene expression	Usp48	0.15	1	0.18	4.2e-05	-5.97	2.38e-09	0.3	FALSE
LHb	Rap1gap	gene expression	Rap1gap	0.25	15	0.25	1.1e-06	5.64	1.67e-08	0.54	FALSE
Liver	Rap1gap	alternative TSS	XM_017593408.2	0.02	1	0.01	3.9e-02	5.29	1.20e-07	0.03	FALSE
Liver	Wnt4	alternative TSS	NM_053402.2	0.02	1	0	2.6e-01	-5.8	6.70e-09	0.07	FALSE
Liver	Ece1	gene expression	Ece1	0.04	926	0.02	1.4e-03	-5.28	1.30e-07	0.53	FALSE
Liver	Hspg2	gene expression	Hspg2	0.04	2	0.05	3.9e-06	5.27	1.37e-07	0.43	FALSE
Liver	Rap1gap	gene expression	Rap1gap	0.46	37	0.22	4.6e-24	5.28	1.32e-07	0.53	FALSE
NAcc	Rap1gap	alternative TSS	NM_001415933.1	0.07	1	0.07	2.3e-08	-5.29	1.19e-07	0.37	FALSE
NAcc	Rap1gap	alternative TSS	XM_017593412.2	0.2	1	0.26	1.3e-29	5.29	1.19e-07	0.38	FALSE
NAcc	Rap1gap	alternative TSS	NM_001415933.1	0.18	1	0.19	4.9e-21	-5.29	1.19e-07	0.38	FALSE
NAcc	Rap1gap	alternative TSS	XM_017593412.2	0.23	1	0.28	3.0e-32	5.29	1.19e-07	0.38	FALSE
NAcc	Ece1	gene expression	Ece1	0.17	926	0.17	2.5e-19	-5.23	1.69e-07	0.38	FALSE
NAcc	Rap1gap	gene expression	Rap1gap	0.06	1146	0.06	7.8e-08	-5.21	1.88e-07	0.4	FALSE
NAcc	Rap1gap	isoform ratio	XM_017593412.2	0.16	1	0.2	3.3e-23	5.29	1.19e-07	0.38	FALSE
NAcc	Rap1gap	mRNA stability	Rap1gap	0.12	1	0.14	3.1e-16	5.92	3.14e-09	0.95	FALSE
OFC	Eif4g3	mRNA stability	Eif4g3	0.15	808	0.04	3.4e-02	-5.34	9.23e-08	0.38	FALSE
PL	Cdc42	alternative polyA	NM_171994.5	0.02	1	0.03	3.9e-04	5.97	2.38e-09	0.39	FALSE
PL	Cdc42	alternative polyA	XM_008764287.3	0.03	1	0.03	4.2e-04	-5.27	1.34e-07	0.04	FALSE
PL	Ece1	gene expression	Ece1	0.1	926	0.08	5.3e-09	-5.24	1.59e-07	0.5	FALSE
PL	Ldlrad2	gene expression	Ldlrad2	0.02	1292	0.01	9.0e-03	5.27	1.33e-07	0.38	FALSE
PL	Usp48	gene expression	Usp48	0.1	1	0.13	6.5e-14	-5.31	1.13e-07	0.39	FALSE
PL	Rap1gap	mRNA stability	Rap1gap	0.11	1146	0.12	8.4e-13	-5.36	8.27e-08	0.52	FALSE
pVTA	Ece1	gene expression	Ece1	0.22	1	0.18	2.8e-08	5.96	2.49e-09	0.96	FALSE
pVTA	Ece1	intron excision ratio	chr5_150126242_150133824	0.09	926	0.04	1.0e-02	-5.32	1.03e-07	0.38	FALSE
pVTA	Ece1	intron excision ratio	chr5_150133272_150133824	0.09	926	0.04	1.1e-02	5.32	1.03e-07	0.36	FALSE