chr5:120,724,181-123,494,906

Trait: Left kidney weight

Best TWAS P=3.10e-09 · Best GWAS P=4.34e-07 conditioned to 7.94e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Ttc4 gene expression Ttc4 0.04 1505 0.01 1.6e-02 -5.68 1.36e-08 0.44 FALSE
BLA Lrp8 alternative polyA XM_039111159.1 0.05 2199 0.02 3.3e-02 5.2 2.02e-07 0.37 FALSE
Brain Cimap2 gene expression Cimap2 0.05 167 0.04 8.7e-05 -5.26 1.41e-07 0.55 FALSE
Brain Yipf1 gene expression Yipf1 0.07 3 0.03 5.3e-04 5.31 1.10e-07 0.54 FALSE
Brain Ttc4 isoform ratio NM_001395043.1 0.07 1507 0.09 1.3e-08 -5.38 7.30e-08 0.63 FALSE
Brain Ttc4 isoform ratio XM_039110294.1 0.07 1507 0.09 1.3e-08 5.37 7.84e-08 0.63 FALSE
Brain Acot11 mRNA stability Acot11 0.14 224 0.16 4.1e-15 5.26 1.42e-07 0.6 FALSE
OFC Lrp8 gene expression Lrp8 0.2 2199 0.06 1.5e-02 -5.33 9.97e-08 0.3 FALSE
OFC Podn gene expression Podn 0.42 435 0.19 2.5e-05 5.49 4.06e-08 0.53 FALSE
OFC Ift25 intron excision ratio chr5_122042021_122044128 0.24 2093 0.04 4.9e-02 -5.35 8.84e-08 0.24 FALSE
PL Slc1a7 alternative polyA NM_001108973.1 0.02 3 0.02 3.5e-03 -5.27 1.33e-07 0.37 FALSE
PL Acot11 intron excision ratio chr5_121527746_121528459 0.02 1642 0.02 5.3e-03 5.2 2.02e-07 0.48 FALSE
pVTA Acot11 gene expression Acot11 0.27 1642 0.15 7.4e-07 -5.93 3.10e-09 0.58 TRUE
pVTA Ttc4 gene expression Ttc4 0.22 1507 0.12 8.1e-06 -5.42 6.00e-08 0.57 FALSE
pVTA Ttc4 isoform ratio NM_001395043.1 0.08 1507 0.04 8.3e-03 -5.71 1.14e-08 0.46 FALSE
pVTA Ttc4 isoform ratio XM_039110294.1 0.08 1507 0.04 7.6e-03 5.67 1.47e-08 0.48 FALSE
pVTA Acot11 mRNA stability Acot11 0.11 1642 0.08 3.5e-04 -5.58 2.40e-08 0.31 FALSE