Hub : Traits : Left kidney weight : ← : →

chr1:267,374,316-270,504,995

Trait: Left kidney weight

Best TWAS P = 6.57e-17 · Best GWAS P= 6.57e-17 conditioned to NaN

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Dennd10	gene expression	Dennd10	0.04	1	0.04	4.7e-05	-6.72	1.84e-11	0.02	FALSE
Adipose	Grk5	gene expression	Grk5	0.19	1480	0.24	3.9e-26	7.01	2.45e-12	0	FALSE
Adipose	LOC120100068	gene expression	LOC120100068	0.03	1	0.02	4.3e-03	-6.08	1.19e-09	0.03	FALSE
Adipose	Prdx3	gene expression	Prdx3	0.19	1	0.24	1.6e-26	-6.23	4.78e-10	0	FALSE
Adipose	Sfxn4	gene expression	Sfxn4	0.02	1	0.02	2.5e-03	-6.57	5.17e-11	0.03	FALSE
Adipose	Zfp933l1	gene expression	Zfp933l1	0.05	19	0.06	4.1e-07	6.89	5.56e-12	0	FALSE
Adipose	Emx2os	intron excision ratio	chr1_268557371_268612388	0.03	1	0.01	1.7e-02	-5.82	5.73e-09	0.03	FALSE
Adipose	Emx2os	mRNA stability	Emx2os	0.19	16	0.15	2.0e-16	-6.13	8.85e-10	0	FALSE
Adipose	LOC120100068	mRNA stability	LOC120100068	0.31	2143	0.18	1.8e-19	7.29	3.16e-13	0	FALSE
BLA	Ces2c	gene expression	Ces2c	0.25	1	0.17	2.6e-09	6.98	2.90e-12	0.94	FALSE
BLA	Emx2os	gene expression	Emx2os	0.38	1	0.21	3.7e-11	-5.9	3.66e-09	0	FALSE
BLA	Rab11fip2	gene expression	Rab11fip2	0.1	2416	0.04	2.2e-03	-6.8	1.03e-11	0.21	FALSE
BLA	Sfxn4	gene expression	Sfxn4	0.07	1	0.02	3.4e-02	8.35	6.57e-17	0.18	TRUE
BLA	Emx2os	mRNA stability	Emx2os	0.3	26	0.12	9.6e-07	-6.31	2.82e-10	0.02	FALSE
BLA	LOC120100068	mRNA stability	LOC120100068	0.37	1	0.11	3.2e-06	5.9	3.74e-09	0.03	FALSE
BLA	Rab11fip2	mRNA stability	Rab11fip2	0.09	1	0.06	3.9e-04	-6.29	3.14e-10	0.04	FALSE
Brain	Ces2c	gene expression	Ces2c	0.23	1	0.27	2.7e-25	6.71	1.91e-11	0.7	FALSE
Brain	Nanos1	gene expression	Nanos1	0.11	1686	0.09	1.3e-08	-6.28	3.36e-10	0.82	TRUE
Brain	Rab11fip2	gene expression	Rab11fip2	0.1	1	0.06	3.8e-06	-7.22	5.10e-13	0.04	FALSE
Brain	Sfxn4	gene expression	Sfxn4	0.07	1433	0.08	4.5e-08	5.36	8.50e-08	0.19	FALSE
Brain	Zfp933l1	gene expression	Zfp933l1	0.05	2	0.06	5.6e-06	6.86	6.81e-12	0.04	FALSE
Brain	Cacul1	isoform ratio	NM_001014248.2	0.11	36	0.1	1.6e-09	5.75	8.75e-09	0.87	FALSE
Brain	Cacul1	isoform ratio	NM_001416001.1	0.1	1	0.08	3.5e-08	-8.24	1.79e-16	0.93	FALSE
Brain	Cacul1	intron excision ratio	chr1_269663603_269672274	0.11	1	0.08	4.3e-08	8.24	1.79e-16	0.93	FALSE
Brain	LOC134485267	intron excision ratio	chr1_269851730_269854168	0.02	1	0.03	1.9e-03	6.88	5.86e-12	0.03	FALSE
Brain	Emx2os	mRNA stability	Emx2os	0.26	84	0.17	1.8e-15	-5.26	1.40e-07	0	FALSE
Brain	Grk5	mRNA stability	Grk5	0.03	1480	0.02	2.3e-03	-7.53	5.21e-14	0.17	FALSE
Brain	LOC120100068	mRNA stability	LOC120100068	0.5	9	0.2	1.0e-18	6.89	5.73e-12	0	FALSE
IC	Ces2c	gene expression	Ces2c	0.26	1	0.22	1.9e-09	6.93	4.35e-12	0.91	FALSE
IC	Emx2os	gene expression	Emx2os	0.57	1	0.39	1.1e-17	-5.65	1.59e-08	0	TRUE
IC	Grk5	gene expression	Grk5	0.12	1	0.07	7.4e-04	8.1	5.50e-16	0.13	FALSE
IC	Cacul1	isoform ratio	NM_001014248.2	0.1	5	0.04	8.5e-03	7.88	3.21e-15	0.64	FALSE
IC	Cacul1	isoform ratio	NM_001416001.1	0.1	1	0.06	1.1e-03	-6.74	1.56e-11	0.04	FALSE
IL	Ces2c	gene expression	Ces2c	0.38	1	0.3	5.3e-08	6.98	2.90e-12	0.85	FALSE
IL	Sfxn4	mRNA stability	Sfxn4	0.51	1	0.22	4.5e-06	6.71	2.01e-11	0.05	FALSE
LHb	Ces2c	gene expression	Ces2c	0.26	73	0.21	1.2e-05	6.92	4.47e-12	0.61	FALSE
LHb	Rab11fip2	gene expression	Rab11fip2	0.24	1	0.1	2.3e-03	-7.22	5.10e-13	0.05	FALSE
Liver	Nanos1	gene expression	Nanos1	0.08	1	0.06	5.6e-07	-6.34	2.36e-10	0	FALSE
Liver	Cacul1	isoform ratio	NM_001014248.2	0.03	1822	0.01	7.0e-03	5.75	8.80e-09	0.32	FALSE
Liver	Ces2c	mRNA stability	Ces2c	0.02	1	0.01	7.1e-03	-6.77	1.26e-11	0.04	FALSE
Liver	Grk5	mRNA stability	Grk5	0.03	1480	0.01	3.6e-02	-6.16	7.30e-10	0.23	FALSE
NAcc	Ces2c	gene expression	Ces2c	0.15	105	0.21	1.0e-31	7.11	1.16e-12	0.78	FALSE
NAcc	Eno4	gene expression	Eno4	0.1	1	0	1.3e-01	5.31	1.12e-07	0.04	FALSE
NAcc	LOC134485266	gene expression	LOC134485266	0.2	1	0.12	2.3e-18	5.58	2.46e-08	0	FALSE
NAcc	Prlhr	gene expression	Prlhr	0.16	116	0.15	5.0e-22	7.06	1.67e-12	0.7	FALSE
NAcc	Rab11fip2	gene expression	Rab11fip2	0.02	1	0.02	1.6e-03	-6.36	2.01e-10	0.02	FALSE
NAcc	Sfxn4	gene expression	Sfxn4	0.05	14	0.06	1.5e-09	7.96	1.72e-15	0.34	TRUE
NAcc	Cacul1	isoform ratio	NM_001014248.2	0.16	1	0.05	9.7e-08	8.23	1.82e-16	0.93	FALSE
NAcc	LOC134485267	intron excision ratio	chr1_269851730_269854168	0.07	1717	0.04	5.0e-07	6.15	7.90e-10	0.68	TRUE
NAcc	Emx2os	mRNA stability	Emx2os	0.07	1	0.07	1.6e-10	-5.85	4.89e-09	0	FALSE
NAcc	Grk5	mRNA stability	Grk5	0.04	1	0.05	9.3e-08	-6.6	4.07e-11	0	FALSE
OFC	Grk5	alternative TSS	XM_039088827.2	0.1	1	0.13	7.1e-04	6.87	6.46e-12	0.05	FALSE
OFC	Ces2c	gene expression	Ces2c	0.29	1	0.3	5.7e-08	6.61	3.73e-11	0.29	FALSE
OFC	Rab11fip2	gene expression	Rab11fip2	0.27	164	0.21	8.5e-06	-7.55	4.46e-14	0.41	TRUE
OFC	Rab11fip2	mRNA stability	Rab11fip2	0.27	21	0.18	6.0e-05	-6.96	3.47e-12	0.44	FALSE
PL	Ces2c	gene expression	Ces2c	0.64	31	0.37	6.6e-43	6.77	1.32e-11	0.76	FALSE
PL	Emx2os	gene expression	Emx2os	0.43	2	0.31	5.9e-35	-5.83	5.60e-09	0	FALSE
PL	Nanos1	gene expression	Nanos1	0.11	1686	0.06	1.9e-07	-5.27	1.37e-07	0.39	FALSE
PL	Sfxn4	gene expression	Sfxn4	0.1	1433	0.1	4.4e-11	6.93	4.26e-12	0.22	FALSE
PL	Zfp933l1	gene expression	Zfp933l1	0.05	74	0.03	2.2e-04	5.96	2.59e-09	0.06	FALSE
PL	Cacul1	isoform ratio	NM_001014248.2	0.02	1822	0.01	1.3e-02	8.12	4.62e-16	0.67	FALSE
PL	Emx2os	mRNA stability	Emx2os	0.22	15	0.12	3.0e-13	-5.94	2.83e-09	0	FALSE
pVTA	Ces2c	gene expression	Ces2c	0.34	1	0.35	2.5e-29	6.67	2.53e-11	0.64	FALSE
pVTA	Emx2os	gene expression	Emx2os	0.25	1	0.12	1.0e-09	-5.94	2.83e-09	0	FALSE
pVTA	Sfxn4	gene expression	Sfxn4	0.06	1433	0.04	3.2e-04	7.17	7.57e-13	0.41	FALSE
pVTA	Grk5	mRNA stability	Grk5	0.06	1480	0.05	6.5e-05	-7.7	1.41e-14	0.43	FALSE