Best TWAS P=1.89e-07 · Best GWAS P=1.62e-07 conditioned to 1.00e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Plpp3 | gene expression | ENSRNOG00000008116 | 0.19 | 6 | 0.05 | 3.2e-06 | -5.1 | 3.44e-07 | 0.47 | FALSE |
| Liver | C8b | gene expression | ENSRNOG00000007639 | 0.08 | 20 | 0.06 | 1.0e-06 | -5.21 | 1.89e-07 | 0.46 | TRUE |
| Liver | AABR07049503.1 | isoform ratio | ENSRNOT00000087040 | 0.45 | 1 | 0.36 | 4.0e-42 | -5.09 | 3.53e-07 | 0.56 | FALSE |
| Liver | AABR07049503.1 | intron excision ratio | chr5:120008720:120009113 | 0.03 | 1 | 0.01 | 4.0e-02 | 5.13 | 2.84e-07 | 0.03 | FALSE |
| PL | Plpp3 | gene expression | ENSRNOG00000008116 | 0.09 | 3 | 0.05 | 1.5e-04 | 5.15 | 2.61e-07 | 0.45 | FALSE |