Hub : Traits : Left kidney weight : ← : →

chr2:27,820,144-32,046,739

Trait: Left kidney weight

Best TWAS P = 1.95e-09 · Best GWAS P= 1.78e-09 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Enc1	gene expression	Enc1	0.03	5	0.02	4.2e-03	5.33	9.83e-08	0.22	FALSE
Adipose	F2rl1	gene expression	F2rl1	0.54	2881	0.35	6.0e-41	-5.21	1.89e-07	0.6	FALSE
Adipose	Ankra2	mRNA stability	Ankra2	0.02	1	0.02	2.6e-03	-5.57	2.59e-08	0.07	FALSE
BLA	LOC102551152	gene expression	LOC102551152	0.08	1	0.06	3.1e-04	5.22	1.75e-07	0.04	FALSE
BLA	Arhgef28	isoform ratio	NM_001415065.1	0.08	1	0.07	1.3e-04	5.81	6.09e-09	0.17	FALSE
BLA	Arhgef28	intron excision ratio	chr2_31227347_31234535	0.09	2237	0.06	5.3e-04	5.24	1.62e-07	0.24	FALSE
BLA	Arhgef28	mRNA stability	Arhgef28	0.2	1	0.16	5.9e-09	5.38	7.63e-08	0.22	FALSE
Brain	LOC102551152	gene expression	LOC102551152	0.13	1	0.21	3.8e-19	5.22	1.75e-07	0.1	TRUE
Brain	LOC134485820	gene expression	LOC134485820	0.22	1	0.23	6.9e-21	5.23	1.68e-07	0.24	FALSE
Brain	LOC102550768	isoform ratio	XR_005500529.2	0.07	44	0.13	3.8e-12	5.54	3.01e-08	0.13	FALSE
Brain	LOC102550768	intron excision ratio	chr2_30576265_30576827	0.05	1	0.01	3.6e-02	5.8	6.59e-09	0.07	FALSE
Brain	LOC102550768	intron excision ratio	chr2_30578924_30580812	0.17	22	0.27	4.1e-25	-5.22	1.79e-07	0.06	FALSE
Brain	Arhgef28	mRNA stability	Arhgef28	0.09	185	0.1	1.7e-09	5.35	9.02e-08	0.26	FALSE
Brain	LOC102551152	mRNA stability	LOC102551152	0.04	3042	0.05	1.8e-05	-5.39	7.18e-08	0.23	FALSE
Brain	Polk	mRNA stability	Polk	0.04	29	0.05	2.7e-05	-5.39	7.01e-08	0.38	FALSE
IC	LOC102550768	isoform ratio	XR_005500528.2	0.39	2408	0.32	8.4e-14	-5.4	6.49e-08	0.21	FALSE
IC	LOC102550768	intron excision ratio	chr2_30578798_30580812	0.26	19	0.29	1.3e-12	5.63	1.78e-08	0.55	FALSE
IC	LOC102550768	intron excision ratio	chr2_30578924_30579840	0.5	25	0.4	3.0e-18	5.35	8.96e-08	0.27	FALSE
IC	LOC102550768	intron excision ratio	chr2_30578924_30580812	0.45	1	0.3	4.1e-13	5.4	6.67e-08	0.22	FALSE
IC	LOC102550768	intron excision ratio	chr2_30579883_30580812	0.5	62	0.46	4.3e-21	-5.59	2.29e-08	0.34	FALSE
IC	Arhgef28	mRNA stability	Arhgef28	0.07	2055	0.06	1.7e-03	-5.26	1.43e-07	0.35	FALSE
IL	Utp15	gene expression	Utp15	0.19	2177	0.17	6.1e-05	5.21	1.85e-07	0.31	FALSE
IL	LOC102550768	intron excision ratio	chr2_30578924_30580812	0.29	1	0.13	6.4e-04	5.4	6.67e-08	0.05	FALSE
IL	LOC102550768	intron excision ratio	chr2_30579883_30580812	0.13	1	0.11	1.1e-03	-5.75	8.73e-09	0.06	FALSE
IL	LOC102550768	mRNA stability	LOC102550768	0.61	42	0.27	4.2e-07	5.31	1.13e-07	0.52	FALSE
LHb	Ankra2	mRNA stability	Ankra2	0.19	1	0.11	1.5e-03	-5.81	6.35e-09	0.1	FALSE
Liver	Polk	alternative polyA	XM_039101672.2	0.11	30	0.13	1.4e-14	-5.75	8.89e-09	0.34	FALSE
Liver	Ankdd1b	gene expression	Ankdd1b	0.02	1	0.01	6.1e-02	-5.21	1.92e-07	0.03	FALSE
Liver	LOC102551152	gene expression	LOC102551152	0.15	1	0.07	3.8e-08	5.31	1.10e-07	0.15	FALSE
Liver	LOC120100671	gene expression	LOC120100671	0.33	1	0.28	9.3e-31	-5.26	1.45e-07	0.49	FALSE
Liver	Nsa2	gene expression	Nsa2	0.03	1	0.02	2.5e-03	5.37	7.83e-08	0.09	FALSE
Liver	Utp15	gene expression	Utp15	0.02	2177	0.02	2.0e-03	5.22	1.82e-07	0.41	FALSE
Liver	Polk	isoform ratio	NM_138516.1	0.06	39	0.05	5.2e-06	-5.54	3.08e-08	0.28	FALSE
Liver	Polk	isoform ratio	XM_039101672.2	0.06	14	0.05	2.4e-06	5.53	3.28e-08	0.27	FALSE
Liver	Iqgap2	mRNA stability	Iqgap2	0.19	3376	0.15	1.0e-16	-5.22	1.76e-07	0.39	TRUE
NAcc	LOC102550768	intron excision ratio	chr2_30467590_30469768	0.03	27	0.03	1.6e-05	-5.96	2.59e-09	0.4	FALSE
NAcc	LOC120100677	intron excision ratio	chr2_30467590_30469768	0.03	27	0.03	1.6e-05	-6	1.95e-09	0.39	TRUE
NAcc	LOC134485824	intron excision ratio	chr2_30467590_30469768	0.03	27	0.03	1.6e-05	-6	1.96e-09	0.39	FALSE
NAcc	LOC102550768	mRNA stability	LOC102550768	0.14	4	0.19	1.1e-27	5.26	1.44e-07	0.04	FALSE
OFC	LOC102551027	gene expression	LOC102551027	0.17	1	0.13	5.3e-04	-5.86	4.60e-09	0.07	FALSE
OFC	LOC102550768	isoform ratio	XR_005500530.2	0.32	2763	0.07	9.4e-03	-5.26	1.47e-07	0.23	TRUE
OFC	LOC102550768	intron excision ratio	chr2_30578798_30580812	0.24	168	0.18	4.2e-05	5.7	1.22e-08	0.4	FALSE
OFC	LOC102550768	intron excision ratio	chr2_30579883_30580812	0.47	131	0.43	1.9e-11	-5.72	1.08e-08	0.47	FALSE
OFC	LOC102550768	mRNA stability	LOC102550768	0.45	92	0.38	5.7e-10	-5.71	1.16e-08	0.54	FALSE
PL	Ankdd1b	alternative TSS	XM_039103462.2	0.11	39	0.09	1.1e-09	-5.25	1.51e-07	0.1	FALSE
PL	Ankdd1b	alternative TSS	XM_039103459.2	0.05	19	0.07	1.5e-08	5.31	1.08e-07	0.39	FALSE
PL	Ankdd1b	alternative TSS	XM_039103462.2	0.11	60	0.16	9.4e-17	-5.34	9.20e-08	0.32	FALSE
PL	Ankdd1b	gene expression	Ankdd1b	0.22	24	0.31	5.7e-35	5.54	2.99e-08	0.36	FALSE
PL	LOC102551152	gene expression	LOC102551152	0.05	18	0.07	6.9e-08	-5.6	2.11e-08	0.48	FALSE
PL	Ankra2	isoform ratio	NM_207595.2	0.05	51	0.01	7.8e-03	-5.24	1.57e-07	0.4	FALSE
PL	LOC102550768	isoform ratio	XR_001836540.3	0.38	37	0.46	2.2e-55	5.23	1.69e-07	0.04	FALSE
PL	LOC102550768	isoform ratio	XR_005500528.2	0.23	23	0.23	3.8e-25	-5.38	7.56e-08	0.06	TRUE
PL	LOC102550768	isoform ratio	XR_005500530.2	0.03	1	0.03	4.8e-04	5.58	2.37e-08	0.15	FALSE
PL	Utp15	isoform ratio	XM_039102170.2	0.02	1	0.03	2.5e-04	-5.34	9.05e-08	0.03	FALSE
PL	Arhgef28	intron excision ratio	chr2_31227347_31234535	0.06	39	0.08	8.9e-09	-5.42	6.11e-08	0.09	FALSE
PL	LOC120100677	intron excision ratio	chr2_30467590_30478990	0.02	1	0.03	2.5e-04	5.36	8.20e-08	0.04	FALSE
PL	LOC134485824	intron excision ratio	chr2_30467590_30478990	0.02	1	0.03	2.5e-04	5.36	8.22e-08	0.04	FALSE
PL	Arhgef28	mRNA stability	Arhgef28	0.26	1	0.08	6.6e-09	5.9	3.69e-09	0.84	FALSE
pVTA	Polk	alternative polyA	NM_138516.1	0.12	95	0.12	1.3e-09	-5.84	5.14e-09	0.48	FALSE
pVTA	Polk	alternative polyA	XM_039101672.2	0.12	90	0.12	1.3e-09	5.77	7.76e-09	0.48	FALSE
pVTA	LOC102551152	gene expression	LOC102551152	0.05	20	0.04	3.9e-04	-5.39	7.03e-08	0.32	FALSE
pVTA	Arhgef28	intron excision ratio	chr2_31227347_31234535	0.04	2055	0.03	2.2e-03	5.21	1.85e-07	0.35	FALSE