Hub : Traits : Left kidney weight : →

chr1:72,902,361-77,357,366

Trait: Left kidney weight

Best TWAS P=4.30e-09 · Best GWAS P=1.22e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Lig1	gene expression	ENSRNOG00000014193	0.11	13	0.08	4.0e-09	5.44	5.21e-08	0.6	FALSE
Adipose	Lig1	isoform ratio	ENSRNOT00000019799	0.08	1398	0.04	4.2e-05	5.47	4.57e-08	0.62	FALSE
Adipose	Ehd2	intron excision ratio	chr1:76656052:76656522	0.07	1	0.06	4.2e-07	5.66	1.51e-08	0.93	FALSE
BLA	Lig1	gene expression	ENSRNOG00000014193	0.34	1	0.19	2.0e-10	5.46	4.71e-08	0.64	FALSE
BLA	Lig1	isoform ratio	ENSRNOT00000019799	0.17	1	0.09	2.4e-05	5.46	4.82e-08	0.26	FALSE
BLA	Lig1	isoform ratio	ENSRNOT00000109652	0.19	34	0.09	1.3e-05	-5.46	4.78e-08	0.66	TRUE
BLA	Lig1	intron excision ratio	chr1:74202463:74203983	0.07	1	0.02	3.3e-02	5.51	3.57e-08	0.04	FALSE
BLA	Lig1	intron excision ratio	chr1:74203426:74203983	0.07	1	0.02	4.5e-02	-5.51	3.57e-08	0.04	FALSE
BLA	Lig1	mRNA stability	ENSRNOG00000014193	0.07	1400	0.03	1.1e-02	5.62	1.90e-08	0.46	FALSE
Brain	Lig1	isoform ratio	ENSRNOT00000019799	0.35	33	0.33	3.0e-31	5.82	5.93e-09	0.66	FALSE
Brain	Lig1	isoform ratio	ENSRNOT00000109652	0.34	104	0.33	6.1e-31	-5.87	4.30e-09	0.67	TRUE
Brain	Lig1	intron excision ratio	chr1:74202463:74203983	0.16	9	0.16	1.2e-14	5.73	1.00e-08	0.68	FALSE
Brain	Lig1	intron excision ratio	chr1:74203426:74203983	0.09	7	0.09	7.6e-09	-5.68	1.38e-08	0.69	FALSE
Brain	Zswim9	mRNA stability	ENSRNOG00000014186	0.04	2	0.04	9.3e-05	5.12	3.04e-07	0.64	FALSE
Eye	Lig1	gene expression	ENSRNOG00000014193	0.47	1400	0.18	9.2e-04	5.61	1.97e-08	0.45	FALSE
IL	Lig1	isoform ratio	ENSRNOT00000109652	0.29	5	0.28	2.3e-07	-5.48	4.25e-08	0.41	TRUE
LHb	Lig1	gene expression	ENSRNOG00000014193	0.18	1	0.16	1.5e-04	5.51	3.51e-08	0.09	FALSE
LHb	Lig1	isoform ratio	ENSRNOT00000019799	0.3	3	0.13	5.9e-04	5.6	2.17e-08	0.64	FALSE
LHb	Lig1	isoform ratio	ENSRNOT00000109652	0.45	1	0.31	5.0e-08	-5.52	3.38e-08	0.34	FALSE
LHb	Lig1	mRNA stability	ENSRNOG00000014193	0.32	1376	0.18	3.9e-05	5.1	3.36e-07	0.57	TRUE
Liver	Cabp5	alternative polyA	ENSRNOT00000096394	0.03	1	0.02	3.4e-03	-5.53	3.29e-08	0.05	FALSE
Liver	Sult2a2	alternative polyA	ENSRNOT00000052129	0.16	1	0.1	6.1e-11	-5.53	3.17e-08	0.99	FALSE
Liver	Sult2a2	alternative polyA	ENSRNOT00000089371	0.15	1	0.1	1.1e-10	5.53	3.17e-08	0.99	FALSE
Liver	AC107531.3	alternative polyA	ENSRNOT00000015108	0.1	1	0.05	2.4e-06	-5.44	5.25e-08	0.7	FALSE
Liver	AC107531.3	alternative polyA	ENSRNOT00000107542	0.09	1	0.05	6.4e-06	5.44	5.25e-08	0.7	FALSE
Liver	Sult2a2	alternative TSS	ENSRNOT00000041367	0.17	4	0.12	2.3e-13	-5.46	4.90e-08	0.99	FALSE
Liver	Sult2a2	alternative TSS	ENSRNOT00000052129	0.16	4	0.12	3.4e-13	5.42	5.98e-08	0.99	FALSE
Liver	AC107531.3	alternative TSS	ENSRNOT00000107542	0.16	1222	0.13	1.2e-14	5.12	3.09e-07	0.62	FALSE
Liver	AC107531.3	alternative TSS	ENSRNOT00000117195	0.16	1222	0.13	1.3e-14	-5.18	2.28e-07	0.65	FALSE
Liver	Cabp5	gene expression	ENSRNOG00000014787	0.69	70	0.39	1.8e-45	5.31	1.09e-07	0.07	FALSE
Liver	Selenow	gene expression	ENSRNOG00000067799	0.66	885	0.24	2.1e-26	5.55	2.86e-08	0.86	FALSE
Liver	Lig1	isoform ratio	ENSRNOT00000109652	0.08	9	0.06	2.3e-07	-5.6	2.09e-08	0.7	FALSE
Liver	Sult2a2	isoform ratio	ENSRNOT00000052129	0.22	3	0.13	2.3e-14	-5.5	3.90e-08	0.99	FALSE
Liver	Sult2a2	isoform ratio	ENSRNOT00000089371	0.21	1	0.13	3.4e-14	5.49	3.91e-08	0.99	FALSE
Liver	Sult2a2	isoform ratio	ENSRNOT00000112779	0.2	3	0.12	2.9e-13	-5.5	3.90e-08	0.99	FALSE
Liver	ENSRNOG00000070843	isoform ratio	ENSRNOT00000104720	0.03	269	0.01	1.0e-02	-5.75	8.83e-09	0.76	FALSE
NAcc	AABR07002065.2	alternative polyA	ENSRNOT00000094704	0.29	4	0.07	6.0e-06	5.51	3.62e-08	0.03	TRUE
NAcc	Lig1	gene expression	ENSRNOG00000014193	0.05	1399	0.02	7.1e-03	5.18	2.25e-07	0.35	FALSE
NAcc	Lig1	isoform ratio	ENSRNOT00000109652	0.08	1399	0.04	6.7e-04	-5.61	1.97e-08	0.63	FALSE
OFC	Lig1	gene expression	ENSRNOG00000014193	0.22	2	0.11	1.4e-03	5.45	4.93e-08	0.4	FALSE
OFC	Lig1	isoform ratio	ENSRNOT00000109652	0.17	1	0.07	1.0e-02	-5.47	4.39e-08	0.06	FALSE
PL	Lig1	gene expression	ENSRNOG00000014193	0.28	1399	0.16	3.7e-12	5.35	8.71e-08	0.61	FALSE
PL	Lig1	isoform ratio	ENSRNOT00000019799	0.25	1	0.17	9.6e-13	5.51	3.57e-08	0.7	FALSE
PL	Lig1	isoform ratio	ENSRNOT00000109652	0.3	1	0.22	9.2e-17	-5.51	3.57e-08	0.7	FALSE
PL	Lig1	intron excision ratio	chr1:74202463:74203983	0.1	1399	0.07	6.1e-06	5.27	1.39e-07	0.68	FALSE