Hub : Traits : Pavlov. Cond. change in total contacts : ← →

chr1:154,277,716-157,352,620

Trait: Pavlov. Cond. change in total contacts

Best TWAS P=9.084761e-08 · Best GWAS P=1.523388e-07 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Mrpl48	alternative polyA	ENSRNOT00000024290	0.05	0.03	lasso	9	0.04	2.2e-05	3.5	-5.2	2.1e-07	-0.58	0.95	0.04	TRUE
2	Adipose	P2ry2	alternative polyA	ENSRNOT00000026115	0.03	0.02	top1	1	0.02	4.7e-03	-5.2	-5.2	2.4e-07	0.98	0.05	0.05	FALSE
3	Adipose	P2ry2	alternative polyA	ENSRNOT00000114931	0.03	0.02	top1	1	0.02	4.4e-03	-5.2	5.2	2.4e-07	-0.98	0.05	0.05	FALSE
4	Adipose	Mrpl48	alternative TSS	ENSRNOT00000024290	0.08	0.06	lasso	1	0.06	1.7e-07	3.5	-5.2	1.5e-07	-0.38	0.99	0.01	FALSE
5	Adipose	Mrpl48	alternative TSS	ENSRNOT00000097667	0.08	0.06	lasso	1	0.06	1.2e-07	3.5	5.2	1.5e-07	0.43	0.99	0.01	FALSE
6	Adipose	Mrpl48	alternative TSS	ENSRNOT00000024290	0.08	0.06	lasso	1	0.06	1.1e-07	3.5	-5.2	1.5e-07	-0.39	0.99	0.01	FALSE
7	Adipose	Mrpl48	alternative TSS	ENSRNOT00000097667	0.08	0.06	lasso	1	0.06	1.4e-07	3.5	5.2	1.5e-07	0.41	0.99	0.01	FALSE
8	Adipose	Clpb	gene expression	ENSRNOG00000019693	0.16	0.05	blup	1569	0.11	1.9e-12	-5.0	5.3	1.2e-07	-0.86	0.32	0.68	FALSE
9	Adipose	Arap1	mRNA stability	ENSRNOG00000019555	0.06	0.03	top1	1	0.03	4.4e-04	-5.2	-5.2	2.5e-07	0.97	0.10	0.23	TRUE
10	Brain	Clpb	gene expression	ENSRNOG00000019693	0.59	0.46	blup	1569	0.62	2.7e-72	3.8	5.2	2.5e-07	-0.80	0.94	0.06	FALSE
11	Brain	Numa1	mRNA stability	ENSRNOG00000000417	0.34	0.29	blup	1574	0.30	2.8e-28	-5.1	5.3	1.3e-07	-0.95	0.31	0.69	FALSE
12	IL	Inppl1	intron excision ratio	chr1:156186418:156186665	0.30	0.01	lasso	6	0.05	2.9e-02	-5.0	5.3	1.5e-07	-0.93	0.24	0.29	FALSE
13	Liver	Mrpl48	alternative polyA	ENSRNOT00000024290	0.03	0.02	top1	1	0.02	2.3e-03	-5.2	5.2	2.5e-07	-0.94	0.06	0.08	FALSE
14	Liver	Mrpl48	alternative polyA	ENSRNOT00000110624	0.04	0.02	top1	1	0.02	1.7e-03	-5.2	-5.2	2.5e-07	0.95	0.06	0.10	FALSE
15	Liver	Mrpl48	alternative polyA	ENSRNOT00000024290	0.05	0.02	top1	1	0.03	7.8e-04	-5.2	5.2	2.5e-07	-0.96	0.07	0.15	FALSE
16	Liver	Mrpl48	alternative polyA	ENSRNOT00000110624	0.06	0.03	top1	1	0.03	5.6e-04	-5.2	-5.2	2.5e-07	0.95	0.07	0.20	FALSE
17	Liver	Atg16l2	gene expression	ENSRNOG00000019413	0.02	0.00	blup	1649	0.01	5.5e-02	-5.2	-5.3	9.5e-08	0.96	0.24	0.46	FALSE
18	Liver	Nup98	gene expression	ENSRNOG00000020347	0.22	0.05	blup	1360	0.08	1.2e-09	-4.9	5.1	2.8e-07	-0.85	0.25	0.75	FALSE
19	Liver	Pgap2	gene expression	ENSRNOG00000020371	0.47	0.29	lasso	27	0.36	4.3e-42	-5.0	5.2	2.1e-07	-0.89	0.22	0.78	FALSE
20	Liver	Rhog	gene expression	ENSRNOG00000020393	0.21	0.14	blup	1398	0.14	1.7e-15	-4.9	5.2	1.8e-07	-0.94	0.23	0.77	FALSE
21	Liver	Stim1	gene expression	ENSRNOG00000020425	0.54	0.29	lasso	53	0.38	3.5e-44	-4.7	5.2	1.7e-07	-0.87	0.23	0.77	FALSE
22	Liver	Numa1	mRNA stability	ENSRNOG00000000417	0.04	0.01	enet	3	0.02	4.6e-03	-5.0	5.2	2.3e-07	-0.89	0.32	0.61	TRUE
23	Liver	Atg16l2	mRNA stability	ENSRNOG00000019413	0.04	0.00	blup	1649	0.00	8.8e-02	-5.0	-5.3	9.1e-08	0.94	0.29	0.58	TRUE
24	Liver	Pgap2	mRNA stability	ENSRNOG00000020371	0.04	0.02	blup	1358	0.02	4.5e-03	-4.8	5.2	1.6e-07	-0.95	0.22	0.67	FALSE
25	NAcc	Arap1	gene expression	ENSRNOG00000019555	0.07	0.05	top1	1	0.05	9.2e-05	-5.2	5.2	1.5e-07	-0.90	0.09	0.29	FALSE
26	PL	Numa1	mRNA stability	ENSRNOG00000000417	0.21	0.14	blup	1571	0.15	1.3e-11	-4.9	5.3	1.1e-07	-0.90	0.32	0.68	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.