chr1:154,320,012-157,330,368

Trait: Pavlov. Cond. change in total contacts

Best TWAS P=2.8e-08 · Best GWAS P=1.52e-07 conditioned to 2.08e-02

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h²	# weights	Model R²	Model R² P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	P2ry6	alternative TSS	XM_006229712.3	0.05	1	0.02	1.6e-03	5.19	2.14e-07	0.09	FALSE
Adipose	Relt	gene expression	Relt	0.05	28	0.03	1.7e-04	-5.37	7.75e-08	0.73	FALSE
Adipose	Numa1	mRNA stability	Numa1	0.19	1592	0.14	2.7e-15	5.29	1.24e-07	0.68	FALSE
Brain	Plekhb1	alternative TSS	NM_172033.2	0.19	1	0.17	1.1e-15	-5.22	1.82e-07	0.91	FALSE
Brain	Plekhb1	alternative TSS	XM_006229791.3	0.19	1	0.17	6.5e-16	5.22	1.82e-07	0.91	FALSE
Brain	Clpb	gene expression	Clpb	0.5	1572	0.54	8.2e-59	5.23	1.71e-07	0.62	FALSE
Brain	LOC120097348	gene expression	LOC120097348	0.22	3	0.18	1.3e-16	-5.25	1.51e-07	0.7	FALSE
Brain	Numa1	mRNA stability	Numa1	0.28	1594	0.26	3.6e-24	5.33	9.85e-08	0.68	FALSE
LHb	LOC120097346	gene expression	LOC120097346	0.17	1589	0.03	5.7e-02	5.19	2.11e-07	0.28	FALSE
Liver	Art2b	gene expression	Art2b	0.03	1	0.02	3.4e-03	-5.18	2.24e-07	0.04	FALSE
Liver	LOC120097346	gene expression	LOC120097346	0.09	1	0.07	5.1e-08	-5.19	2.14e-07	0.82	FALSE
Liver	LOC120097348	gene expression	LOC120097348	0.03	136	0.01	1.7e-02	5.18	2.21e-07	0.44	FALSE
Liver	Pgap2	gene expression	Pgap2	0.51	45	0.41	3.7e-48	5.21	1.84e-07	0.78	FALSE
Liver	Rhog	gene expression	Rhog	0.18	1399	0.12	4.3e-13	5.2	2.03e-07	0.77	FALSE
Liver	LOC120099897	intron excision ratio	chr1_155953549_155953974	0.05	1534	0.03	1.1e-04	-5.23	1.66e-07	0.46	FALSE
Liver	LOC120099897	intron excision ratio	chr1_155953549_155954326	0.24	1534	0.17	7.2e-19	5.27	1.38e-07	0.67	FALSE
Liver	Numa1	mRNA stability	Numa1	0.05	1592	0.02	1.4e-03	5.27	1.33e-07	0.53	FALSE
NAcc	Arap1	alternative TSS	XM_006229900.3	0.03	1625	0.03	3.8e-04	5.39	7.02e-08	0.62	FALSE
NAcc	Arap1	alternative TSS	XM_006229900.3	0.03	1625	0.03	5.2e-04	5.25	1.48e-07	0.46	FALSE
NAcc	Arap1	gene expression	Arap1	0.07	5	0.06	3.5e-07	-5.26	1.47e-07	0.73	FALSE
NAcc	LOC120097348	gene expression	LOC120097348	0.03	1567	0.02	9.7e-04	-5.18	2.19e-07	0.42	FALSE
NAcc	Arap1	isoform ratio	XM_006229900.3	0.04	1625	0.04	1.6e-05	5.37	7.72e-08	0.71	FALSE
NAcc	Numa1	mRNA stability	Numa1	0.08	1594	0.06	2.3e-07	5.32	1.04e-07	0.68	FALSE
PL	Folr2	gene expression	Folr2	0.07	8	0.04	5.4e-05	5.55	2.80e-08	0.68	TRUE
PL	LOC120097348	gene expression	LOC120097348	0.14	1567	0.1	2.8e-11	-5.31	1.07e-07	0.69	FALSE
PL	LOC120099897	intron excision ratio	chr1_155953549_155954326	0.34	8	0.36	4.1e-41	5.37	8.02e-08	0.66	FALSE
PL	LOC120099897	intron excision ratio	chr1_155961507_155979290	0.31	1534	0.3	5.6e-34	-5.36	8.43e-08	0.64	FALSE
PL	Numa1	mRNA stability	Numa1	0.14	12	0.11	3.4e-12	5.38	7.51e-08	0.69	FALSE
pVTA	LOC120097348	gene expression	LOC120097348	0.18	6	0.09	1.6e-04	-5.31	1.10e-07	0.68	FALSE