chr1:163,689,834-166,745,856

Trait: Pavlov. Cond. change in total contacts

Best TWAS P = 2.53e-08 · Best GWAS P= 3.09e-08 conditioned to 1e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h²	# weights	Model R²	Model R² P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Clpb	gene expression	Clpb	0.11	1605	0.08	8.4e-09	5.38	7.62e-08	0.67	FALSE
Adipose	Relt	gene expression	Relt	0.06	63	0.03	1.2e-04	5.38	7.65e-08	0.77	FALSE
Adipose	Plekhb1	isoform ratio	XM_063272775.1	0.23	314	0.12	4.5e-13	-5.23	1.72e-07	0	FALSE
Adipose	Arap1	mRNA stability	Arap1	0.06	1	0.03	1.1e-04	-5.39	6.90e-08	0.58	FALSE
Adipose	Numa1	mRNA stability	Numa1	0.18	1634	0.13	1.2e-14	5.3	1.15e-07	0.68	FALSE
BLA	LOC120099897	alternative polyA	XR_005499356.2	0.09	1	0.05	1.4e-03	5.39	7.15e-08	0.1	FALSE
BLA	Rab6a	isoform ratio	NM_001414455.1	0.05	14	0.04	5.7e-03	5.25	1.48e-07	0.25	FALSE
BLA	Rab6a	isoform ratio	NM_053366.2	0.06	2	0.04	2.9e-03	-5.31	1.08e-07	0.28	TRUE
BLA	Arhgef17	intron excision ratio	chr1_164664222_164668333	0.14	33	0.09	1.1e-05	-5.38	7.37e-08	0.6	FALSE
BLA	Fam168a	intron excision ratio	chr1_164489566_164554337	0.12	79	0.05	1.1e-03	5.24	1.60e-07	0.66	FALSE
Brain	Numa1	gene expression	Numa1	0.14	1	0.11	1.5e-10	-5.22	1.81e-07	0.79	FALSE
Brain	LOC120099897	isoform ratio	XR_005499356.2	0.03	1	0.03	1.8e-03	5.26	1.45e-07	0.07	FALSE
Brain	Fam168a	intron excision ratio	chr1_164594486_164599642	0.05	1	0.05	1.8e-05	5.54	3.09e-08	0.68	FALSE
Brain	Numa1	mRNA stability	Numa1	0.29	1634	0.27	5.4e-25	5.39	7.23e-08	0.68	FALSE
Eye	Numa1	mRNA stability	Numa1	0.5	49	0.1	1.3e-02	5.39	6.92e-08	0.32	FALSE
IC	LOC120099897	alternative polyA	XR_005499356.2	0.15	11	0.12	7.7e-06	5.39	7.17e-08	0.66	FALSE
IC	LOC120099897	alternative polyA	XR_010060725.1	0.15	40	0.12	1.1e-05	-5.4	6.71e-08	0.66	FALSE
IC	P2ry6	alternative TSS	XM_039078872.2	0.18	3	0.11	3.1e-05	5.54	3.10e-08	0.56	TRUE
IC	Mrpl48	gene expression	Mrpl48	0.23	1	0.18	7.9e-08	-5.31	1.08e-07	0.85	FALSE
IC	Anapc15	mRNA stability	Anapc15	0.14	1600	0.05	3.2e-03	-5.39	7.23e-08	0.6	FALSE
IL	Mrpl48	gene expression	Mrpl48	0.41	1	0.11	1.5e-03	-5.54	3.09e-08	0.09	FALSE
Liver	LOC120099897	alternative polyA	XR_005499356.2	0.22	58	0.17	1.8e-18	5.46	4.86e-08	0.67	FALSE
Liver	LOC120099897	alternative polyA	XR_010060725.1	0.22	56	0.17	2.2e-18	-5.41	6.44e-08	0.67	FALSE
Liver	LOC120097346	gene expression	LOC120097346	0.09	1	0.07	1.5e-08	5.4	6.76e-08	0.88	FALSE
Liver	Pgap2	gene expression	Pgap2	0.6	61	0.42	1.0e-50	5.2	1.96e-07	0.78	FALSE
Liver	Rhog	gene expression	Rhog	0.19	1444	0.14	4.5e-15	5.25	1.49e-07	0.77	FALSE
Liver	Rnf121	gene expression	Rnf121	0.04	2	0.02	4.5e-03	-5.34	9.30e-08	0.36	TRUE
Liver	Atg16l2	isoform ratio	XR_010052892.1	0.06	1	0.03	1.1e-04	-5.28	1.26e-07	0.34	FALSE
Liver	LOC120099897	isoform ratio	XR_005499356.2	0.23	192	0.19	4.1e-20	5.55	2.85e-08	0.68	FALSE
Liver	LOC120099897	intron excision ratio	chr1_165365571_165365996	0.05	1558	0.03	3.1e-04	-5.27	1.39e-07	0.46	FALSE
Liver	LOC120099897	intron excision ratio	chr1_165365571_165366348	0.24	1558	0.18	2.3e-19	5.3	1.13e-07	0.66	FALSE
Liver	LOC120099897	intron excision ratio	chr1_165365601_165365996	0.1	115	0.07	2.6e-08	-5.57	2.53e-08	0.36	TRUE
Liver	Numa1	mRNA stability	Numa1	0.05	1634	0.02	8.9e-04	5.34	9.13e-08	0.58	FALSE
Liver	Pgap2	mRNA stability	Pgap2	0.06	1398	0.02	1.3e-03	5.31	1.10e-07	0.7	FALSE
NAcc	Arap1	gene expression	Arap1	0.05	1656	0.04	6.1e-07	5.46	4.67e-08	0.74	FALSE
NAcc	Chrna10	gene expression	Chrna10	0.02	1411	0.01	5.0e-03	5.25	1.53e-07	0.45	FALSE
NAcc	Numa1	mRNA stability	Numa1	0.11	1634	0.09	4.9e-13	5.37	7.99e-08	0.69	FALSE
OFC	LOC120099897	isoform ratio	XR_005499356.2	0.32	1	0.18	3.8e-05	5.33	9.59e-08	0.11	FALSE
PL	LOC120099897	alternative polyA	XR_005499356.2	0.09	1558	0.08	8.1e-09	5.35	9.00e-08	0.65	FALSE
PL	LOC120099897	alternative polyA	XR_010060725.1	0.08	1558	0.07	6.8e-08	-5.38	7.50e-08	0.65	FALSE
PL	LOC120099897	isoform ratio	XR_005499356.2	0.09	1	0.09	1.2e-09	5.22	1.81e-07	0.74	FALSE
PL	Xndc1	isoform ratio	XM_006229906.5	0.03	1563	0.01	1.0e-02	5.34	9.24e-08	0.49	FALSE
PL	LOC120099897	intron excision ratio	chr1_165365571_165365996	0.06	7	0.05	2.0e-06	-5.29	1.20e-07	0.55	TRUE
PL	LOC120099897	intron excision ratio	chr1_165365571_165366348	0.34	1558	0.35	2.7e-40	5.43	5.70e-08	0.65	FALSE
PL	LOC120099897	intron excision ratio	chr1_165373529_165391317	0.33	1558	0.3	2.5e-33	-5.44	5.34e-08	0.63	FALSE
PL	Numa1	mRNA stability	Numa1	0.16	9	0.14	1.5e-14	5.53	3.13e-08	0.69	TRUE
pVTA	P2ry6	alternative TSS	XM_006229712.4	0.23	1	0.2	6.5e-16	-5.31	1.08e-07	0.85	FALSE
pVTA	P2ry6	alternative TSS	XM_039078872.2	0.18	1	0.15	3.3e-12	5.54	3.09e-08	0.95	FALSE
pVTA	Clpb	gene expression	Clpb	0.2	1605	0.22	1.5e-17	5.33	9.66e-08	0.61	FALSE