Best TWAS P=2.64e-08 · Best GWAS P=2.64e-08 conditioned to 1e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | LOC120098581 | alternative TSS | XM_039098179.1 | 0.05 | 12 | 0.02 | 3.7e-03 | 5.44 | 5.33e-08 | 0.82 | TRUE |
| Adipose | Dhps | gene expression | Dhps | 0.09 | 2 | 0.08 | 3.0e-09 | 5.32 | 1.05e-07 | 0.94 | FALSE |
| Adipose | Prdx2 | gene expression | Prdx2 | 0.08 | 1 | 0.07 | 4.0e-08 | 5.37 | 7.95e-08 | 0.84 | FALSE |
| BLA | MAST1 | gene expression | MAST1 | 0.14 | 56 | 0.05 | 8.3e-04 | -5.36 | 8.13e-08 | 0.87 | TRUE |
| BLA | Mri1 | gene expression | Mri1 | 0.29 | 3 | 0.24 | 4.7e-13 | 5.33 | 9.64e-08 | 0.8 | TRUE |
| BLA | Brme1 | mRNA stability | Brme1 | 0.11 | 1 | 0.07 | 2.0e-04 | 5.5 | 3.87e-08 | 0.28 | FALSE |
| Brain | Gcdh | gene expression | Gcdh | 0.52 | 22 | 0.55 | 2.3e-60 | -5.19 | 2.12e-07 | 0.89 | FALSE |
| Brain | Nacc1 | mRNA stability | Nacc1 | 0.03 | 1202 | 0.02 | 2.8e-03 | 5.3 | 1.13e-07 | 0.7 | FALSE |
| IL | LOC102555451 | gene expression | LOC102555451 | 0.53 | 10 | 0.28 | 2.1e-07 | 5.19 | 2.12e-07 | 0.82 | FALSE |
| Liver | Adgrl1 | alternative TSS | XM_039097967.1 | 0.03 | 1 | 0.03 | 5.3e-04 | 5.43 | 5.75e-08 | 0.18 | FALSE |
| Liver | Gcdh | gene expression | Gcdh | 0.5 | 15 | 0.34 | 2.7e-39 | -5.45 | 5.15e-08 | 0.89 | FALSE |
| Liver | Get3 | gene expression | Get3 | 0.04 | 1 | 0.01 | 9.1e-03 | -5.31 | 1.09e-07 | 0.04 | TRUE |
| Liver | Wdr83os | gene expression | Wdr83os | 0.17 | 1 | 0.12 | 1.3e-13 | -5.31 | 1.09e-07 | 0.86 | FALSE |
| Liver | Syce2 | mRNA stability | Syce2 | 0.11 | 133 | 0.09 | 1.1e-09 | -5.48 | 4.34e-08 | 0.88 | FALSE |
| NAcc | LOC120098586 | gene expression | LOC120098586 | 0.04 | 1 | 0.03 | 3.0e-04 | 5.55 | 2.82e-08 | 0.37 | FALSE |
| NAcc | Mri1 | gene expression | Mri1 | 0.22 | 8 | 0.19 | 2.3e-21 | 5.54 | 2.94e-08 | 0.85 | FALSE |
| NAcc | Gcdh | intron excision ratio | chr19_23263340_23263398 | 0.04 | 1 | 0.04 | 3.5e-05 | 5.5 | 3.87e-08 | 0.5 | FALSE |
| NAcc | Gcdh | intron excision ratio | chr19_23263527_23263608 | 0.04 | 1 | 0.04 | 2.4e-05 | -5.55 | 2.82e-08 | 0.62 | FALSE |
| NAcc | Gadd45gip1 | mRNA stability | Gadd45gip1 | 0.06 | 1 | 0.03 | 7.0e-05 | 5.55 | 2.82e-08 | 0.62 | FALSE |
| NAcc | Gcdh | mRNA stability | Gcdh | 0.05 | 777 | 0.03 | 4.3e-04 | 5.18 | 2.16e-07 | 0.84 | FALSE |
| OFC | Mri1 | gene expression | Mri1 | 0.27 | 1 | 0.07 | 8.4e-03 | -5.56 | 2.64e-08 | 0.09 | TRUE |
| OFC | Gcdh | intron excision ratio | chr19_23264057_23264177 | 0.22 | 777 | 0.01 | 2.0e-01 | 5.38 | 7.27e-08 | 0.36 | FALSE |
| PL | C19h19orf53 | gene expression | C19h19orf53 | 0.06 | 1 | 0.05 | 4.5e-06 | -5.41 | 6.25e-08 | 0.76 | FALSE |
| PL | LOC102555451 | gene expression | LOC102555451 | 0.3 | 127 | 0.26 | 5.9e-29 | -5.3 | 1.18e-07 | 0.88 | FALSE |
| PL | Mri1 | gene expression | Mri1 | 0.13 | 1522 | 0.11 | 1.7e-12 | 5.26 | 1.41e-07 | 0.79 | FALSE |
| PL | Gadd45gip1 | mRNA stability | Gadd45gip1 | 0.12 | 144 | 0.09 | 5.5e-10 | 5.19 | 2.08e-07 | 0.8 | FALSE |