Hub : Traits : Light reinforcement 1 : ← : →

chr19:33,034,804-36,281,759

Trait: Light reinforcement 1

Best TWAS P = 1.93e-08 · Best GWAS P= 1.71e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Adcy7	gene expression	Adcy7	0.03	40	0.02	9.5e-04	5.26	1.41e-07	0.49	FALSE
Adipose	LOC134483298	gene expression	LOC134483298	0.05	1	0.05	1.5e-06	-5.27	1.39e-07	0.33	FALSE
Adipose	Zfp423	mRNA stability	Zfp423	0.02	1	0.02	9.0e-04	-5.24	1.58e-07	0.04	FALSE
BLA	Cyld	gene expression	Cyld	0.38	63	0.39	7.0e-22	-5.21	1.88e-07	0.46	FALSE
BLA	Cyld	isoform ratio	XM_063278092.1	0.13	1	0.1	8.7e-06	-5.41	6.26e-08	0.25	FALSE
BLA	Cyld	intron excision ratio	chr19_34538944_34546479	0.28	47	0.19	2.7e-10	-5.26	1.46e-07	0.43	FALSE
BLA	Cyld	intron excision ratio	chr19_34538944_34547074	0.14	1	0.07	2.1e-04	-5.25	1.54e-07	0.05	FALSE
BLA	Snx20	mRNA stability	Snx20	0.08	1873	0.07	2.0e-04	5.34	9.28e-08	0.45	FALSE
Brain	Adcy7	alternative polyA	NM_053396.1	0.4	1	0.04	5.7e-05	5.24	1.59e-07	0.05	FALSE
Brain	Adcy7	alternative polyA	XM_017601393.3	0.41	1	0.04	6.0e-05	-5.24	1.59e-07	0.05	FALSE
Brain	Adcy7	alternative polyA	NM_053396.1	0.42	1	0.04	7.4e-05	5.24	1.59e-07	0.05	FALSE
Brain	Adcy7	alternative polyA	XM_017601393.3	0.41	1	0.04	5.3e-05	-5.24	1.59e-07	0.05	FALSE
Brain	Adcy7	alternative TSS	XM_063278326.1	0.47	1	0.03	5.2e-04	-5.24	1.59e-07	0.41	TRUE
Brain	Cyld	alternative TSS	XM_039097803.2	0.18	40	0.28	1.4e-26	5.37	8.04e-08	0.41	FALSE
Brain	Cyld	alternative TSS	XM_063278099.1	0.1	28	0.15	1.2e-13	-5.42	5.97e-08	0.42	FALSE
Brain	Brd7	gene expression	Brd7	0.08	1	0.1	2.3e-09	5.24	1.59e-07	0.34	FALSE
Brain	Cyld	gene expression	Cyld	0.52	1	0.63	5.0e-75	5.39	7.09e-08	0.51	FALSE
Brain	LOC102553576	gene expression	LOC102553576	0.06	2088	0.07	4.4e-07	5.26	1.48e-07	0.41	FALSE
Brain	LOC102557216	gene expression	LOC102557216	0.1	1	0.15	2.9e-14	5.3	1.18e-07	0.39	FALSE
Brain	LOC103694298	gene expression	LOC103694298	0.04	1	0.04	1.6e-04	5.38	7.38e-08	0.12	FALSE
Brain	LOC120098652	gene expression	LOC120098652	0.05	1353	0.04	2.0e-04	-5.28	1.30e-07	0.66	FALSE
Brain	LOC134483298	gene expression	LOC134483298	0.06	1	0.08	9.7e-08	-5.25	1.53e-07	0.34	FALSE
Brain	Nkd1	gene expression	Nkd1	0.04	1862	0.04	1.3e-04	5.39	7.05e-08	0.44	FALSE
Brain	Nod2	gene expression	Nod2	0.22	165	0.3	3.0e-28	5.24	1.61e-07	0.54	FALSE
Brain	Cyld	isoform ratio	XM_063278084.1	0.08	1	0.1	8.1e-10	5.38	7.38e-08	0.5	FALSE
Brain	Cyld	intron excision ratio	chr19_34538944_34546479	0.1	1813	0.13	2.1e-12	-5.32	1.03e-07	0.39	FALSE
Brain	Cyld	mRNA stability	Cyld	0.09	1	0.06	5.0e-06	5.25	1.53e-07	0.29	FALSE
Brain	Nkd1	mRNA stability	Nkd1	0.07	1862	0.09	2.5e-08	-5.36	8.43e-08	0.48	FALSE
Brain	Sall1	mRNA stability	Sall1	0.24	1	0.32	1.0e-30	5.43	5.52e-08	0.6	FALSE
Brain	Snx20	mRNA stability	Snx20	0.11	1873	0.17	6.3e-16	5.35	8.81e-08	0.42	FALSE
Eye	Nkd1	gene expression	Nkd1	0.27	32	0.13	5.3e-03	-5.26	1.42e-07	0.28	FALSE
IC	Cyld	alternative TSS	XM_039097803.2	0.09	1561	0.07	7.1e-04	5.37	7.86e-08	0.41	FALSE
IC	Cyld	gene expression	Cyld	0.41	11	0.38	3.7e-17	-5.3	1.16e-07	0.42	TRUE
IC	LOC120098652	gene expression	LOC120098652	0.07	72	0.06	2.1e-03	5.33	9.70e-08	0.48	FALSE
IC	Cyld	intron excision ratio	chr19_34538944_34546479	0.11	1	0.12	1.3e-05	5.23	1.69e-07	0.07	FALSE
IC	Sall1	mRNA stability	Sall1	0.26	1835	0.26	3.2e-11	-5.36	8.48e-08	0.45	FALSE
IL	Zfp423	gene expression	Zfp423	0.26	1	0.22	4.3e-06	5.62	1.93e-08	0.38	TRUE
IL	Cyld	isoform ratio	XM_063278098.1	0.39	1	0.35	3.8e-09	5.22	1.84e-07	0.16	FALSE
LHb	LOC102557216	gene expression	LOC102557216	0.19	1	0.03	7.5e-02	5.22	1.84e-07	0.05	FALSE
LHb	LOC134483298	gene expression	LOC134483298	0.15	1	0.01	1.5e-01	-5.38	7.40e-08	0.05	FALSE
LHb	Nod2	gene expression	Nod2	0.36	1	0.23	2.9e-06	5.3	1.14e-07	0.08	FALSE
LHb	Snx20	gene expression	Snx20	0.3	1	0.17	6.6e-05	-5.38	7.40e-08	0.06	FALSE
LHb	Cyld	isoform ratio	XM_063278098.1	0.23	26	0.07	1.1e-02	-5.32	1.02e-07	0.35	FALSE
Liver	LOC120098514	alternative polyA	XR_005496770.2	0.09	1	0.01	1.4e-02	-5.28	1.32e-07	0.04	FALSE
Liver	Nkd1	gene expression	Nkd1	0.04	1	0.04	7.5e-05	-5.35	9.01e-08	0.07	FALSE
Liver	LOC102553576	isoform ratio	XR_005496994.2	0.03	1	0.03	2.5e-04	-5.22	1.84e-07	0.11	FALSE
Liver	LOC102553576	intron excision ratio	chr19_34181608_34181739	0.16	1	0.2	9.8e-22	-5.53	3.15e-08	0.72	FALSE
NAcc	Cyld	alternative TSS	XM_063278099.1	0.09	31	0.11	1.9e-16	5.28	1.30e-07	0.38	FALSE
NAcc	Adcy7	gene expression	Adcy7	0.03	22	0.02	2.9e-04	-5.24	1.61e-07	0.47	FALSE
NAcc	Cyld	gene expression	Cyld	0.13	24	0.15	1.0e-22	-5.4	6.80e-08	0.48	FALSE
NAcc	LOC134483298	gene expression	LOC134483298	0.03	1	0.03	6.0e-05	-5.3	1.14e-07	0.11	FALSE
NAcc	Nkd1	gene expression	Nkd1	0.02	1	0.01	6.4e-03	-5.25	1.54e-07	0.04	FALSE
NAcc	Zfp423	gene expression	Zfp423	0.1	29	0.1	5.8e-15	-5.38	7.52e-08	0.62	TRUE
NAcc	Cyld	isoform ratio	XM_063278092.1	0.1	1	0.12	9.4e-18	-5.29	1.25e-07	0.37	FALSE
NAcc	Cyld	isoform ratio	XM_063278098.1	0.66	1	0.54	6.5e-99	5.38	7.40e-08	0.5	FALSE
NAcc	Cyld	intron excision ratio	chr19_34512070_34518374	0.02	1	0.02	2.9e-04	-5.35	8.61e-08	0.04	FALSE
NAcc	Cyld	intron excision ratio	chr19_34538944_34541714	0.01	1	0.01	1.0e-02	-5.41	6.26e-08	0.03	FALSE
NAcc	Cyld	intron excision ratio	chr19_34538944_34546479	0.13	1813	0.17	1.4e-24	-5.36	8.13e-08	0.51	FALSE
NAcc	Cyld	intron excision ratio	chr19_34538944_34547074	0.03	1813	0.02	8.5e-04	5.25	1.53e-07	0.41	FALSE
NAcc	LOC102553576	intron excision ratio	chr19_34181608_34181739	0.05	1	0.07	2.8e-10	-5.39	7.04e-08	0.54	FALSE
NAcc	Zfp423	intron excision ratio	chr19_35467812_35555134	0.04	1	0.02	2.9e-04	-5.35	8.84e-08	0.06	FALSE
NAcc	Nkd1	mRNA stability	Nkd1	0.03	1862	0.02	2.1e-04	-5.29	1.22e-07	0.46	FALSE
NAcc	Sall1	mRNA stability	Sall1	0.29	47	0.26	5.6e-40	-5.23	1.69e-07	0.43	FALSE
OFC	Nod2	alternative polyA	XM_063277867.1	0.12	1	0.05	2.1e-02	5.26	1.43e-07	0.05	FALSE
OFC	Cyld	isoform ratio	XM_063278098.1	0.15	1	0.1	1.9e-03	5.39	7.04e-08	0.05	FALSE
OFC	Sall1	mRNA stability	Sall1	0.32	1	0.27	3.2e-07	5.38	7.39e-08	0.35	FALSE
PL	Cyld	alternative TSS	XM_039097803.2	0.12	103	0.11	7.6e-12	-5.36	8.54e-08	0.48	FALSE
PL	Cyld	alternative TSS	XM_063278099.1	0.07	28	0.08	7.2e-09	-5.31	1.07e-07	0.46	FALSE
PL	Cyld	gene expression	Cyld	0.48	95	0.44	3.1e-52	-5.32	1.02e-07	0.49	FALSE
PL	LOC134483298	gene expression	LOC134483298	0.02	1888	0.01	1.0e-02	5.38	7.42e-08	0.36	FALSE
PL	LOC134483301	gene expression	LOC134483301	0.04	1704	0.03	3.6e-04	-5.27	1.35e-07	0.59	FALSE
PL	Nkd1	gene expression	Nkd1	0.05	1	0.04	3.7e-05	-5.3	1.14e-07	0.2	FALSE
PL	Tent4b	gene expression	Tent4b	0.04	1	0.03	2.5e-04	-5.24	1.58e-07	0.04	FALSE
PL	Zfp423	gene expression	Zfp423	0.75	1353	0.2	1.9e-21	-5.33	9.62e-08	0.74	FALSE
PL	Cyld	isoform ratio	XM_063278092.1	0.05	1	0.05	5.2e-06	-5.26	1.43e-07	0.15	FALSE
PL	Cyld	intron excision ratio	chr19_34512070_34518374	0.03	1	0.02	6.0e-03	-5.37	7.69e-08	0.03	FALSE
PL	Cyld	intron excision ratio	chr19_34538944_34546479	0.13	1813	0.14	9.4e-15	-5.39	7.19e-08	0.47	FALSE
PL	Cyld	intron excision ratio	chr19_34538944_34547074	0.04	37	0.02	1.4e-03	-5.35	8.78e-08	0.46	FALSE
PL	Nkd1	mRNA stability	Nkd1	0.02	1862	0.01	1.2e-02	-5.38	7.38e-08	0.35	FALSE
PL	Sall1	mRNA stability	Sall1	0.25	16	0.27	9.2e-30	-5.28	1.33e-07	0.5	FALSE
PL	Snx20	mRNA stability	Snx20	0.02	1	0.02	5.9e-03	-5.32	1.02e-07	0.03	FALSE
pVTA	Cyld	gene expression	Cyld	0.21	41	0.27	3.8e-22	-5.4	6.69e-08	0.46	FALSE
pVTA	LOC134483298	gene expression	LOC134483298	0.08	1	0.1	1.6e-08	-5.35	8.84e-08	0.46	FALSE
pVTA	Nkd1	gene expression	Nkd1	0.17	47	0.13	5.7e-11	5.35	8.60e-08	0.47	FALSE
pVTA	Zfp423	gene expression	Zfp423	0.16	1	0.13	1.1e-10	5.5	3.87e-08	0.69	FALSE
pVTA	LOC102553576	isoform ratio	XR_010060119.1	0.03	2088	0.01	2.5e-02	5.28	1.31e-07	0.4	FALSE
RMTg	LOC102553576	gene expression	LOC102553576	0.12	2088	0.06	1.2e-02	5.33	1.01e-07	0.36	FALSE
RMTg	Sall1	mRNA stability	Sall1	0.11	1	0.05	1.7e-02	5.23	1.71e-07	0.05	FALSE