Hub : Traits : Light reinforcement 1 : ← : →

chr19:17,070,407-19,809,408

Trait: Light reinforcement 1

Best TWAS P=8.66e-09 · Best GWAS P=3.09e-09 conditioned to 1e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Adcy7	gene expression	Adcy7	0.02	43	0.02	3.4e-03	5.6	2.09e-08	0.46	FALSE
Adipose	Cnep1r1	gene expression	Cnep1r1	0.06	1	0.03	2.3e-04	5.25	1.56e-07	0.04	FALSE
Adipose	Nkd1	gene expression	Nkd1	0.15	197	0.16	1.6e-17	-5.3	1.16e-07	0.46	FALSE
Adipose	Snx20	gene expression	Snx20	0.06	1	0.05	1.2e-06	-5.3	1.19e-07	0.22	FALSE
BLA	Cyld	alternative TSS	XM_039097803.1	0.11	111	0.11	3.0e-06	-5.36	8.34e-08	0.44	FALSE
BLA	Cyld	gene expression	Cyld	0.39	94	0.46	6.8e-27	-5.34	9.21e-08	0.46	FALSE
BLA	LOC102553576	gene expression	LOC102553576	0.09	1	0.06	2.8e-04	-5.56	2.75e-08	0.14	FALSE
BLA	LOC103694298	gene expression	LOC103694298	0.37	14	0.31	4.2e-17	-5.27	1.33e-07	0.5	FALSE
BLA	Snx20	gene expression	Snx20	0.05	1	0.04	2.6e-03	-5.45	4.99e-08	0.04	FALSE
BLA	Cyld	isoform ratio	XM_039097796.1	0.27	27	0.31	3.2e-17	5.48	4.37e-08	0.46	FALSE
BLA	LOC102553576	isoform ratio	XR_005496992.1	0.07	1	0.04	3.4e-03	5.64	1.70e-08	0.05	FALSE
BLA	Cyld	intron excision ratio	chr19_18338598_18344904	0.12	1	0.1	7.6e-06	-5.19	2.16e-07	0.1	FALSE
BLA	Cyld	intron excision ratio	chr19_18365476_18373011	0.26	1	0.21	2.0e-11	5.55	2.87e-08	0.57	FALSE
BLA	Cyld	intron excision ratio	chr19_18365476_18373606	0.16	1	0.07	9.6e-05	-5.51	3.63e-08	0.07	FALSE
BLA	Nkd1	mRNA stability	Nkd1	0.08	1	0.07	1.2e-04	5.27	1.36e-07	0.06	FALSE
BLA	Snx20	mRNA stability	Snx20	0.08	1	0.07	1.8e-04	-5.3	1.14e-07	0.08	FALSE
BLA	Zfp423	mRNA stability	Zfp423	0.07	1325	0.06	5.0e-04	-5.28	1.27e-07	0.53	TRUE
Brain	Nod2	alternative polyA	NM_001414911.1	0.08	1	0.12	3.0e-11	5.66	1.48e-08	0.72	FALSE
Brain	Nod2	alternative polyA	XM_008772373.3	0.08	1	0.13	1.1e-11	-5.66	1.48e-08	0.72	FALSE
Brain	Cyld	alternative TSS	NM_001017380.1	0.04	1	0.03	1.0e-03	5.51	3.63e-08	0.04	FALSE
Brain	Cyld	alternative TSS	XM_039097803.1	0.18	286	0.28	3.5e-26	-5.44	5.47e-08	0.4	FALSE
Brain	Brd7	gene expression	Brd7	0.09	1	0.12	1.5e-11	5.46	4.78e-08	0.46	FALSE
Brain	Cyld	gene expression	Cyld	0.48	1	0.61	6.3e-71	5.55	2.87e-08	0.57	FALSE
Brain	LOC102553576	gene expression	LOC102553576	0.11	26	0.14	2.9e-13	5.43	5.53e-08	0.39	TRUE
Brain	LOC120098652	gene expression	LOC120098652	0.05	1	0.05	3.6e-05	5.62	1.92e-08	0.34	FALSE
Brain	Nkd1	gene expression	Nkd1	0.04	1835	0.05	2.4e-05	5.47	4.63e-08	0.45	FALSE
Brain	Snx20	gene expression	Snx20	0.17	58	0.23	7.0e-21	5.4	6.73e-08	0.42	FALSE
Brain	Zfp423	gene expression	Zfp423	0.24	1	0.3	6.5e-28	5.68	1.38e-08	0.75	FALSE
Brain	Cyld	isoform ratio	XM_039097796.1	0.13	22	0.2	5.5e-18	5.47	4.63e-08	0.4	FALSE
Brain	LOC102553576	isoform ratio	XR_005496992.1	0.06	2048	0.07	3.8e-07	-5.25	1.54e-07	0.42	FALSE
Brain	Cyld	intron excision ratio	chr19_18338598_18344904	0.03	1	0.03	5.7e-04	-5.5	3.79e-08	0.05	FALSE
Brain	Cyld	intron excision ratio	chr19_18345020_18348718	0.08	1	0.09	2.5e-08	-5.42	5.87e-08	0.4	FALSE
Brain	Cyld	intron excision ratio	chr19_18365476_18373011	0.09	85	0.14	3.9e-13	5.48	4.35e-08	0.38	FALSE
Brain	Nkd1	mRNA stability	Nkd1	0.08	1	0.12	1.2e-11	5.64	1.70e-08	0.69	FALSE
Brain	Snx20	mRNA stability	Snx20	0.11	227	0.17	9.7e-16	-5.46	4.67e-08	0.4	FALSE
Eye	Tent4b	alternative TSS	NM_001401226.1	0.32	1	0.13	5.3e-03	-5.42	5.92e-08	0.06	FALSE
Eye	Nod2	mRNA stability	Nod2	0.25	1	0.22	3.0e-04	5.19	2.16e-07	0.29	TRUE
IL	Cyld	gene expression	Cyld	0.54	18	0.38	4.9e-10	-5.51	3.63e-08	0.45	FALSE
IL	LOC102553576	gene expression	LOC102553576	0.15	1	0.14	2.5e-04	-5.29	1.25e-07	0.05	FALSE
IL	Nod2	gene expression	Nod2	0.16	1835	0.14	2.8e-04	-5.28	1.31e-07	0.41	FALSE
IL	Zfp423	gene expression	Zfp423	0.27	1	0.26	5.3e-07	5.58	2.34e-08	0.25	FALSE
IL	Cyld	isoform ratio	XM_039097796.1	0.19	1	0.2	1.9e-05	-5.34	9.39e-08	0.06	FALSE
IL	Cyld	isoform ratio	XM_039097800.1	0.42	1	0.34	4.9e-09	5.28	1.30e-07	0.13	FALSE
LHb	Cyld	gene expression	Cyld	0.31	1788	0.17	8.6e-05	-5.43	5.58e-08	0.43	FALSE
LHb	Nod2	gene expression	Nod2	0.32	1	0.22	6.3e-06	5.52	3.40e-08	0.08	FALSE
LHb	Snx20	gene expression	Snx20	0.3	1	0.18	5.0e-05	-5.27	1.36e-07	0.05	FALSE
LHb	Cyld	intron excision ratio	chr19_18349933_18360457	0.14	4	0.06	1.2e-02	-5.22	1.79e-07	0.25	TRUE
Liver	LOC102553576	alternative polyA	XR_005496992.1	0.23	1	0.26	3.8e-28	-5.7	1.20e-08	0.78	FALSE
Liver	Nkd1	gene expression	Nkd1	0.03	1	0.04	8.8e-05	-5.44	5.31e-08	0.06	FALSE
Liver	Cyld	isoform ratio	XM_039097801.1	0.02	1786	0.02	5.1e-03	-5.44	5.34e-08	0.31	FALSE
Liver	LOC102553576	isoform ratio	XR_005496994.1	0.16	1	0.22	1.3e-23	-5.33	9.57e-08	0.33	FALSE
Liver	LOC102553576	intron excision ratio	chr19_18008033_18008164	0.17	1	0.2	2.6e-21	-5.51	3.63e-08	0.55	FALSE
Liver	LOC102553576	mRNA stability	LOC102553576	0.43	184	0.51	3.9e-66	-5.51	3.69e-08	0.48	FALSE
Liver	Sall1	mRNA stability	Sall1	0.55	573	0.52	7.6e-68	5.29	1.25e-07	0.45	FALSE
Liver	Zfp423	mRNA stability	Zfp423	0.06	1	0.06	3.7e-07	5.19	2.12e-07	0.18	FALSE
NAcc	Cyld	alternative TSS	XM_039097803.1	0.03	123	0.01	2.4e-02	-5.45	4.92e-08	0.32	FALSE
NAcc	Cyld	gene expression	Cyld	0.15	1	0.2	1.3e-22	5.5	3.79e-08	0.51	FALSE
NAcc	Heatr3	gene expression	Heatr3	0.03	1	0.03	3.0e-04	5.52	3.48e-08	0.07	FALSE
NAcc	LOC102553576	gene expression	LOC102553576	0.13	1	0.12	9.9e-14	-5.44	5.46e-08	0.46	FALSE
NAcc	Snx20	gene expression	Snx20	0.06	1	0.05	2.8e-06	-5.24	1.56e-07	0.18	FALSE
NAcc	Zfp423	gene expression	Zfp423	0.12	1	0.09	1.1e-10	5.45	5.08e-08	0.47	FALSE
NAcc	Cyld	isoform ratio	XM_039097796.1	0.6	1	0.3	7.0e-35	-5.52	3.40e-08	0.53	FALSE
NAcc	Cyld	isoform ratio	XM_039097800.1	0.71	452	0.58	5.2e-82	5.5	3.88e-08	0.52	FALSE
NAcc	Cyld	intron excision ratio	chr19_18338598_18344904	0.06	1788	0.06	1.8e-07	5.48	4.31e-08	0.46	FALSE
NAcc	Cyld	intron excision ratio	chr19_18345020_18348718	0.05	1	0.03	3.5e-04	-5.24	1.57e-07	0.17	FALSE
NAcc	Cyld	intron excision ratio	chr19_18365476_18373011	0.11	1788	0.13	1.3e-14	-5.43	5.64e-08	0.47	FALSE
NAcc	Cyld	intron excision ratio	chr19_18365476_18373513	0.07	1	0.01	2.9e-02	-5.26	1.40e-07	0.03	FALSE
NAcc	LOC102553576	intron excision ratio	chr19_18008033_18008164	0.05	1	0.06	4.1e-07	-5.53	3.22e-08	0.55	FALSE
NAcc	Cyld	mRNA stability	Cyld	0.04	1	0.01	8.0e-03	5.19	2.16e-07	0.03	FALSE
NAcc	LOC102553576	mRNA stability	LOC102553576	0.02	1	0.01	1.5e-02	-5.4	6.83e-08	0.03	FALSE
NAcc	Nkd1	mRNA stability	Nkd1	0.03	1	0.03	2.8e-04	5.52	3.40e-08	0.07	FALSE
NAcc	Sall1	mRNA stability	Sall1	0.23	2049	0.19	2.4e-21	-5.27	1.34e-07	0.54	FALSE
OFC	Zfp423	gene expression	Zfp423	0.53	1	0.41	5.3e-11	5.4	6.56e-08	0.35	FALSE
OFC	Cyld	isoform ratio	XM_039097796.1	0.13	1	0.03	7.9e-02	-5.29	1.26e-07	0.05	FALSE
OFC	Cyld	isoform ratio	XM_039097800.1	0.13	1788	0.04	3.8e-02	-5.4	6.70e-08	0.3	FALSE
PL	Nod2	alternative polyA	NM_001414911.1	0.03	1	0.02	6.1e-03	5.25	1.55e-07	0.03	FALSE
PL	Nod2	alternative polyA	XM_008772373.3	0.03	1	0.02	5.0e-03	-5.25	1.55e-07	0.03	FALSE
PL	Cyld	alternative TSS	NM_001017380.1	0.04	1	0.02	6.0e-03	5.37	7.97e-08	0.03	FALSE
PL	Cyld	alternative TSS	XM_039097803.1	0.09	1	0.09	2.0e-10	-5.37	7.97e-08	0.34	FALSE
PL	Cyld	gene expression	Cyld	0.48	322	0.42	2.8e-50	5.48	4.29e-08	0.51	FALSE
PL	LOC102553576	gene expression	LOC102553576	0.19	2048	0.14	4.3e-15	5.26	1.43e-07	0.5	FALSE
PL	Nkd1	gene expression	Nkd1	0.05	1	0.05	7.2e-06	-5.52	3.48e-08	0.34	FALSE
PL	Tent4b	gene expression	Tent4b	0.04	1	0.04	5.9e-05	-5.76	8.66e-09	0.39	TRUE
PL	Zfp423	gene expression	Zfp423	0.89	1	0.21	9.1e-23	5.68	1.35e-08	0.76	FALSE
PL	Cyld	isoform ratio	XM_039097796.1	0.12	35	0.15	8.8e-16	5.41	6.23e-08	0.48	FALSE
PL	LOC102553576	isoform ratio	XR_005496992.1	0.03	2048	0.02	4.1e-03	-5.45	4.92e-08	0.46	FALSE
PL	Cyld	intron excision ratio	chr19_18338598_18344904	0.07	1	0.06	5.7e-07	-5.45	4.99e-08	0.44	FALSE
PL	Cyld	intron excision ratio	chr19_18365476_18373606	0.04	1788	0.03	4.1e-04	5.44	5.21e-08	0.46	FALSE
PL	Nkd1	mRNA stability	Nkd1	0.02	23	0.02	3.0e-03	5.23	1.72e-07	0.37	FALSE
PL	Sall1	mRNA stability	Sall1	0.19	28	0.19	2.7e-20	-5.55	2.90e-08	0.52	TRUE
PL	Snx20	mRNA stability	Snx20	0.02	1	0.02	2.6e-03	-5.25	1.55e-07	0.03	FALSE
pVTA	Nod2	alternative polyA	NM_001414911.1	0.09	1	0.04	6.0e-03	5.24	1.57e-07	0.04	FALSE
pVTA	Nod2	alternative polyA	XM_008772373.3	0.09	1	0.04	6.7e-03	-5.24	1.57e-07	0.04	FALSE
pVTA	Cyld	gene expression	Cyld	0.16	41	0.16	2.2e-07	-5.4	6.82e-08	0.45	FALSE
pVTA	Nkd1	gene expression	Nkd1	0.24	567	0.08	3.1e-04	-5.18	2.28e-07	0.46	TRUE
pVTA	Zfp423	gene expression	Zfp423	0.13	1325	0.1	5.0e-05	-5.47	4.59e-08	0.63	FALSE
RMTg	LOC102553576	gene expression	LOC102553576	0.18	2048	0.15	8.2e-05	5.32	1.02e-07	0.4	FALSE