Best TWAS P=1.450169e-07 · Best GWAS P=7.12302e-08 conditioned to 4.840436e-37
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | BLA | Lratd1 | isoform ratio | ENSRNOT00000065531 | 0.15 | 0.1 | lasso | 15 | 0.11 | 1.9e-06 | -2.8 | -5.3 | 1.5e-07 | 0.7 | 0.59 | 0.41 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.