Hub : Traits : Left kidney weight : ← : →

chr7:121,227,737-123,235,883

Trait: Left kidney weight

Best TWAS P = 2.42e-08 · Best GWAS P= 1.09e-07 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Rabl2	alternative TSS	XM_006242227.4	0.02	2086	0.01	2.1e-02	5.26	1.42e-07	0.33	FALSE
Adipose	Hdac10	gene expression	Hdac10	0.08	57	0.05	2.6e-06	5.32	1.01e-07	0.28	FALSE
Adipose	Plxnb2	intron excision ratio	chr7_122125188_122127702	0.03	1618	0	8.4e-02	-5.54	3.04e-08	0.42	FALSE
BLA	Dennd6b	alternative polyA	XM_063263948.1	0.13	1627	0.08	7.5e-05	-5.39	6.97e-08	0.3	FALSE
BLA	Dennd6b	alternative polyA	NM_001108749.1	0.14	1627	0.09	2.9e-05	5.4	6.84e-08	0.34	FALSE
BLA	Dennd6b	alternative polyA	XM_063263948.1	0.15	1627	0.09	2.4e-05	-5.3	1.19e-07	0.23	FALSE
BLA	Mapk11	alternative TSS	XM_017595119.3	0.06	1	0.04	3.4e-03	5.31	1.09e-07	0.08	FALSE
BLA	Mapk11	alternative TSS	XM_017595119.3	0.06	1	0.04	4.8e-03	5.31	1.09e-07	0.08	FALSE
BLA	Mapk11	alternative TSS	XM_063264275.1	0.2	1630	0.15	2.2e-08	-5.35	8.98e-08	0.5	FALSE
BLA	Lmf2	gene expression	Lmf2	0.3	16	0.23	2.8e-12	-5.58	2.42e-08	0.64	TRUE
BLA	Dennd6b	isoform ratio	XM_063263948.1	0.14	1627	0.07	9.3e-05	-5.41	6.17e-08	0.34	FALSE
BLA	Mapk11	isoform ratio	XM_017595119.3	0.07	1630	0.04	2.9e-03	5.32	1.03e-07	0.46	FALSE
BLA	Mapk11	isoform ratio	XM_063264275.1	0.2	1630	0.14	6.1e-08	-5.35	8.90e-08	0.53	FALSE
BLA	Selenoo	mRNA stability	Selenoo	0.21	5	0.2	7.5e-11	5.24	1.64e-07	0.37	FALSE
Brain	Rabl2	alternative TSS	XM_006242225.5	0.06	31	0.03	6.3e-04	5.56	2.71e-08	0.35	FALSE
Brain	Ncaph2	gene expression	Ncaph2	0.05	1	0.06	5.3e-06	-5.31	1.09e-07	0.87	TRUE
Brain	Mapk11	isoform ratio	XM_017595119.3	0.05	1630	0.03	6.3e-04	5.4	6.54e-08	0.31	FALSE
Brain	Selenoo	intron excision ratio	chr7_122051488_122052585	0.04	1652	0.02	6.2e-03	5.35	8.71e-08	0.37	FALSE
Eye	Selenoo	gene expression	Selenoo	0.28	1652	0.06	5.2e-02	5.27	1.38e-07	0.19	FALSE
IC	Lmf2	gene expression	Lmf2	0.33	1937	0.31	1.0e-13	-5.53	3.27e-08	0.47	FALSE
IC	Selenoo	gene expression	Selenoo	0.57	1652	0.5	5.3e-24	5.3	1.16e-07	0.52	FALSE
IC	Mapk11	isoform ratio	XM_063264275.1	0.15	1630	0.12	1.3e-05	-5.48	4.21e-08	0.5	FALSE
IC	Mlc1	mRNA stability	Mlc1	0.5	1687	0.32	6.9e-14	5.24	1.62e-07	0.52	FALSE
IL	Mapk11	gene expression	Mapk11	0.29	1630	0.22	6.8e-06	-5.56	2.71e-08	0.56	FALSE
LHb	Dennd6b	alternative polyA	XM_063263948.1	0.21	82	0.1	2.4e-03	-5.44	5.45e-08	0.1	FALSE
LHb	Lmf2	gene expression	Lmf2	0.46	1	0.28	1.9e-07	-5.31	1.10e-07	0.68	FALSE
LHb	Rabl2	isoform ratio	XM_006242225.5	0.3	2086	0.14	3.1e-04	-5.42	5.93e-08	0.43	FALSE
LHb	Rabl2	intron excision ratio	chr7_122539521_122540104	0.14	6	0.12	8.0e-04	-5.27	1.35e-07	0.42	FALSE
Liver	Mapk11	alternative TSS	XM_063264275.1	0.02	24	0.01	2.7e-02	-5.28	1.27e-07	0.3	FALSE
Liver	Sbf1	gene expression	Sbf1	0.06	1953	0.04	7.9e-05	5.52	3.40e-08	0.58	FALSE
Liver	Mapk11	isoform ratio	XM_017595119.3	0.02	1630	0.02	4.9e-03	5.45	4.94e-08	0.42	FALSE
Liver	Ppp6r2	intron excision ratio	chr7_122187662_122194723	0.03	1656	0.02	2.5e-03	5.49	4.03e-08	0.39	FALSE
Liver	Ppp6r2	mRNA stability	Ppp6r2	0.04	1656	0.03	3.1e-04	-5.42	6.01e-08	0.6	FALSE
NAcc	Lmf2	gene expression	Lmf2	0.31	49	0.31	4.5e-48	-5.36	8.21e-08	0.68	FALSE
NAcc	Sbf1	gene expression	Sbf1	0.03	1953	0.02	1.5e-03	-5.24	1.64e-07	0.38	FALSE
NAcc	Syce3	gene expression	Syce3	0.09	20	0.12	5.0e-18	-5.46	4.64e-08	0.54	FALSE
NAcc	Mapk11	isoform ratio	XM_017595119.3	0.03	1630	0.03	3.6e-05	5.53	3.28e-08	0.5	FALSE
NAcc	Mapk11	isoform ratio	XM_063264275.1	0.1	1630	0.11	1.1e-15	-5.48	4.32e-08	0.49	FALSE
NAcc	Rabl2	isoform ratio	XM_006242227.4	0.02	1	0.02	1.5e-04	5.24	1.59e-07	0.3	FALSE
NAcc	Mapk11	intron excision ratio	chr7_122103922_122104837	0.03	156	0.01	2.6e-03	-5.29	1.19e-07	0.15	FALSE
NAcc	Ppp6r2	mRNA stability	Ppp6r2	0.03	1656	0.01	4.8e-03	-5.37	7.69e-08	0.34	FALSE
PL	Ttll8	alternative TSS	XM_063264699.1	0.13	1649	0.12	9.0e-13	5.26	1.44e-07	0.67	FALSE
PL	Ttll8	alternative TSS	XM_063264699.1	0.13	1649	0.11	2.0e-12	5.26	1.45e-07	0.7	FALSE
PL	Ppp6r2	mRNA stability	Ppp6r2	0.08	10	0.03	2.2e-04	-5.31	1.11e-07	0.48	FALSE
PL	Shank3	mRNA stability	Shank3	0.03	2032	0.03	2.9e-04	-5.26	1.41e-07	0.35	FALSE
pVTA	Rabl2	alternative TSS	XM_006242225.5	0.05	2086	0.07	4.9e-06	-5.27	1.39e-07	0.57	FALSE
pVTA	Lmf2	gene expression	Lmf2	0.35	22	0.51	4.1e-47	-5.31	1.09e-07	0.56	TRUE
pVTA	Selenoo	gene expression	Selenoo	0.5	1652	0.63	9.5e-65	5.22	1.83e-07	0.5	FALSE
pVTA	Trabd	gene expression	Trabd	0.05	62	0.01	3.1e-02	-5.3	1.17e-07	0.1	TRUE
pVTA	Mapk11	intron excision ratio	chr7_122103922_122104837	0.03	1630	0.02	7.7e-03	-5.5	3.89e-08	0.38	FALSE
pVTA	Ppp6r2	mRNA stability	Ppp6r2	0.09	1656	0.07	2.4e-06	-5.3	1.17e-07	0.29	FALSE