Hub : Traits : Tibialis anterior weight : ←

chr15:43,349,498-46,640,839

Trait: Tibialis anterior weight

Best TWAS P=3.72e-08 · Best GWAS P=3.72e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Pdlim2	gene expression	ENSRNOG00000008543	0.04	172	0.02	9.3e-04	5.34	9.50e-08	0.56	FALSE
Adipose	Piwil2	gene expression	ENSRNOG00000009871	0.04	1	0.02	3.1e-03	5.29	1.21e-07	0.05	FALSE
Adipose	Polr3d	gene expression	ENSRNOG00000010028	0.07	246	0.06	8.3e-07	-5.31	1.09e-07	0.63	FALSE
Adipose	Bmp1	gene expression	ENSRNOG00000010890	0.05	1	0.05	1.1e-06	-5.28	1.29e-07	0.59	FALSE
Adipose	Fhip2b	gene expression	ENSRNOG00000012014	0.02	12	0.01	2.8e-02	5.35	8.57e-08	0.56	FALSE
Adipose	Dmtn	gene expression	ENSRNOG00000012273	0.17	1	0.2	1.7e-21	5.32	1.05e-07	0.69	FALSE
Adipose	Slc25a37	gene expression	ENSRNOG00000015495	0.02	52	0.01	8.5e-03	5.32	1.04e-07	0.47	FALSE
Adipose	Loxl2	gene expression	ENSRNOG00000016758	0.02	1	0.01	1.9e-02	5.3	1.17e-07	0.03	FALSE
Adipose	R3hcc1	gene expression	ENSRNOG00000016777	0.15	1	0.09	8.5e-10	-5.28	1.29e-07	0.69	FALSE
Adipose	Chmp7	gene expression	ENSRNOG00000016939	0.38	263	0.35	9.9e-40	5.26	1.47e-07	0.69	FALSE
Adipose	Rhobtb2	gene expression	ENSRNOG00000017373	0.36	182	0.33	1.9e-37	5.31	1.12e-07	0.67	FALSE
Adipose	Tnfrsf10b	gene expression	ENSRNOG00000038483	0.16	1	0.14	1.7e-15	5.18	2.24e-07	0.54	FALSE
Adipose	Fhip2b	isoform ratio	ENSRNOT00000097198	0.02	1	0.01	3.6e-02	5.32	1.05e-07	0.04	FALSE
Adipose	Bin3	isoform ratio	ENSRNOT00000024614	0.06	214	0.05	4.2e-06	5.33	9.90e-08	0.59	FALSE
Adipose	Bin3	isoform ratio	ENSRNOT00000099631	0.07	174	0.05	1.2e-06	-5.33	9.85e-08	0.59	FALSE
Adipose	R3hcc1	mRNA stability	ENSRNOG00000016777	0.28	1	0.17	1.7e-18	-5.28	1.29e-07	0.69	FALSE
BLA	Ppp3cc	alternative polyA	ENSRNOT00000082505	0.07	639	0.03	1.6e-02	5.29	1.23e-07	0.42	FALSE
BLA	Ppp3cc	alternative polyA	ENSRNOT00000091826	0.07	639	0.02	1.9e-02	-5.29	1.23e-07	0.41	FALSE
BLA	Sorbs3	alternative TSS	ENSRNOT00000012056	0.12	711	0.06	4.5e-04	-5.29	1.23e-07	0.55	FALSE
BLA	Sorbs3	alternative TSS	ENSRNOT00000113720	0.12	711	0.06	5.1e-04	5.29	1.23e-07	0.55	FALSE
BLA	Sorbs3	gene expression	ENSRNOG00000008829	0.07	1	0.04	3.5e-03	-5.23	1.66e-07	0.04	FALSE
BLA	Ppp3cc	gene expression	ENSRNOG00000009745	0.51	639	0.31	6.4e-17	5.29	1.20e-07	0.61	FALSE
BLA	Polr3d	gene expression	ENSRNOG00000010028	0.11	588	0.03	1.2e-02	-5.28	1.26e-07	0.58	FALSE
BLA	Lgi3	gene expression	ENSRNOG00000011323	0.14	161	0.08	3.1e-05	-5.31	1.07e-07	0.65	FALSE
BLA	Dmtn	gene expression	ENSRNOG00000012273	0.24	1	0.21	1.8e-11	-5.5	3.72e-08	0.86	TRUE
BLA	R3hcc1	gene expression	ENSRNOG00000016777	0.15	136	0.08	4.0e-05	5.27	1.38e-07	0.69	FALSE
BLA	Rhobtb2	gene expression	ENSRNOG00000017373	0.18	528	0.08	4.5e-05	5.28	1.26e-07	0.65	FALSE
BLA	Ccar2	gene expression	ENSRNOG00000018295	0.11	1	0.06	4.0e-04	5.5	3.72e-08	0.11	FALSE
BLA	Phyhip	intron excision ratio	chr15:45535048:45538056	0.08	572	0.04	5.0e-03	-5.28	1.28e-07	0.46	FALSE
BLA	Dmtn	intron excision ratio	chr15:45694169:45704328	0.05	1	0.02	3.2e-02	-5.21	1.92e-07	0.04	FALSE
BLA	Ppp3cc	mRNA stability	ENSRNOG00000009745	0.08	1	0.04	4.0e-03	5.5	3.72e-08	0.05	FALSE
BLA	Phyhip	mRNA stability	ENSRNOG00000010555	0.07	1	0.05	1.8e-03	5.5	3.72e-08	0.05	FALSE
Brain	Ppp3cc	alternative TSS	ENSRNOT00000091826	0.06	1	0.04	1.4e-04	5.5	3.72e-08	0.42	FALSE
Brain	Ppp3cc	alternative TSS	ENSRNOT00000100817	0.07	1	0.05	8.4e-06	-5.5	3.72e-08	0.68	FALSE
Brain	Ppp3cc	alternative TSS	ENSRNOT00000082505	0.08	1	0.06	1.5e-06	5.5	3.72e-08	0.74	FALSE
Brain	Ppp3cc	alternative TSS	ENSRNOT00000100817	0.08	1	0.06	2.0e-06	-5.5	3.72e-08	0.69	FALSE
Brain	Rhobtb2	alternative TSS	ENSRNOT00000117351	0.03	1	0.01	2.7e-02	5.21	1.91e-07	0.04	FALSE
Brain	Rhobtb2	alternative TSS	ENSRNOT00000023876	0.03	1	0.01	3.8e-02	-5.21	1.91e-07	0.03	FALSE
Brain	Rhobtb2	alternative TSS	ENSRNOT00000117351	0.03	1	0.01	2.9e-02	5.21	1.91e-07	0.04	FALSE
Brain	Sorbs3	gene expression	ENSRNOG00000008829	0.16	118	0.13	5.3e-12	-5.46	4.87e-08	0.58	FALSE
Brain	Ppp3cc	gene expression	ENSRNOG00000009745	0.4	13	0.34	1.3e-32	5.46	4.71e-08	0.61	FALSE
Brain	Slc39a14	gene expression	ENSRNOG00000009832	0.05	1	0.04	1.1e-04	-5.34	9.43e-08	0.08	FALSE
Brain	Polr3d	gene expression	ENSRNOG00000010028	0.17	588	0.13	2.1e-12	-5.29	1.20e-07	0.63	FALSE
Brain	Bmp1	gene expression	ENSRNOG00000010890	0.19	634	0.22	4.3e-20	5.27	1.38e-07	0.65	FALSE
Brain	Lgi3	gene expression	ENSRNOG00000011323	0.1	1	0.1	6.4e-10	-5.28	1.29e-07	0.64	FALSE
Brain	Hr	gene expression	ENSRNOG00000011427	0.02	1	0.02	8.0e-03	-5.28	1.29e-07	0.04	FALSE
Brain	Nudt18	gene expression	ENSRNOG00000011831	0.13	79	0.06	2.5e-06	-5.28	1.27e-07	0.64	FALSE
Brain	Dmtn	gene expression	ENSRNOG00000012273	0.15	172	0.18	1.9e-16	-5.44	5.44e-08	0.67	FALSE
Brain	Entpd4	gene expression	ENSRNOG00000016321	0.07	332	0.05	3.7e-05	-5.31	1.09e-07	0.75	FALSE
Brain	Chmp7	gene expression	ENSRNOG00000016939	0.04	1	0.03	1.9e-03	-5.32	1.03e-07	0.05	FALSE
Brain	Rhobtb2	gene expression	ENSRNOG00000017373	0.31	528	0.26	1.6e-24	5.29	1.22e-07	0.65	FALSE
Brain	Egr3	gene expression	ENSRNOG00000017828	0.04	13	0.03	1.8e-03	-5.37	7.86e-08	0.54	TRUE
Brain	Ccar2	gene expression	ENSRNOG00000018295	0.15	722	0.12	1.6e-11	5.3	1.19e-07	0.58	FALSE
Brain	Tnfrsf10b	gene expression	ENSRNOG00000038483	0.26	479	0.22	8.9e-20	5.28	1.28e-07	0.68	FALSE
Brain	Dmtn	isoform ratio	ENSRNOT00000106565	0.04	1	0.03	5.6e-04	5.38	7.48e-08	0.07	FALSE
Brain	Egr3	isoform ratio	ENSRNOT00000116948	0.03	15	0.02	2.7e-03	5.18	2.24e-07	0.48	FALSE
Brain	Bin3	isoform ratio	ENSRNOT00000024614	0.08	14	0.07	8.4e-07	5.32	1.03e-07	0.58	FALSE
Brain	Bin3	isoform ratio	ENSRNOT00000099631	0.08	1	0.07	5.8e-07	-5.32	1.03e-07	0.52	FALSE
Brain	Ppp3cc	intron excision ratio	chr15:45297492:45298385	0.03	1	0.02	5.2e-03	-5.34	9.43e-08	0.04	FALSE
Brain	Dmtn	intron excision ratio	chr15:45693188:45694000	0.04	1	0.04	4.8e-05	-5.21	1.92e-07	0.1	FALSE
Brain	Dmtn	intron excision ratio	chr15:45693794:45694000	0.03	1	0.02	3.2e-03	5.5	3.72e-08	0.09	FALSE
Brain	Dmtn	intron excision ratio	chr15:45694169:45704328	0.08	685	0.08	4.6e-08	-5.18	2.26e-07	0.66	FALSE
Brain	Dmtn	intron excision ratio	chr15:45702261:45704328	0.06	1	0.08	8.7e-08	5.5	3.72e-08	0.85	FALSE
Brain	Ppp3cc	mRNA stability	ENSRNOG00000009745	0.4	639	0.33	2.7e-31	5.29	1.22e-07	0.61	FALSE
Brain	Slc39a14	mRNA stability	ENSRNOG00000009832	0.07	612	0.06	5.3e-06	-5.28	1.28e-07	0.62	FALSE
Brain	R3hcc1	mRNA stability	ENSRNOG00000016777	0.08	436	0.06	3.0e-06	5.28	1.30e-07	0.7	FALSE
Brain	Chmp7	mRNA stability	ENSRNOG00000016939	0.05	1	0.04	7.7e-05	-5.21	1.91e-07	0.08	FALSE
Brain	Bin3	mRNA stability	ENSRNOG00000018023	0.05	1	0.04	1.2e-04	5.23	1.68e-07	0.06	FALSE
Brain	Ccar2	mRNA stability	ENSRNOG00000018295	0.04	722	0.03	1.4e-03	5.29	1.21e-07	0.53	FALSE
Eye	Phyhip	gene expression	ENSRNOG00000010555	0.77	572	0.52	1.2e-09	-5.28	1.32e-07	0.63	FALSE
Eye	Tnfrsf10b	gene expression	ENSRNOG00000038483	0.37	180	0.25	8.7e-05	5.31	1.12e-07	0.58	FALSE
IL	Ppp3cc	gene expression	ENSRNOG00000009745	0.54	638	0.28	1.7e-07	5.29	1.23e-07	0.61	FALSE
IL	Dmtn	gene expression	ENSRNOG00000012273	0.23	1	0.1	1.9e-03	-5.27	1.33e-07	0.07	FALSE
IL	Rhobtb2	gene expression	ENSRNOG00000017373	0.24	1	0.11	1.6e-03	5.26	1.47e-07	0.47	FALSE
IL	ENSRNOG00000067974	gene expression	ENSRNOG00000067974	0.2	330	0.06	1.2e-02	5.31	1.11e-07	0.44	FALSE
IL	Ppp3cc	mRNA stability	ENSRNOG00000009745	0.33	1	0.13	6.3e-04	5.32	1.03e-07	0.07	FALSE
IL	Bin3	mRNA stability	ENSRNOG00000018023	0.16	713	0.05	2.9e-02	5.29	1.22e-07	0.29	FALSE
LHb	Sorbs3	gene expression	ENSRNOG00000008829	0.22	707	0.11	1.5e-03	-5.29	1.22e-07	0.45	FALSE
LHb	Ppp3cc	gene expression	ENSRNOG00000009745	0.37	637	0.22	7.1e-06	5.29	1.22e-07	0.59	FALSE
LHb	Phyhip	gene expression	ENSRNOG00000010555	0.52	3	0.31	3.9e-08	5.29	1.25e-07	0.64	TRUE
LHb	Tnfrsf10b	gene expression	ENSRNOG00000038483	0.52	1	0.26	8.1e-07	5.27	1.37e-07	0.18	FALSE
LHb	Ppp3cc	mRNA stability	ENSRNOG00000009745	0.28	637	0.12	8.4e-04	5.29	1.23e-07	0.51	FALSE
LHb	Loxl2	mRNA stability	ENSRNOG00000016758	0.16	1	0.08	7.0e-03	-5.26	1.47e-07	0.33	FALSE
Liver	R3hcc1	alternative TSS	ENSRNOT00000022706	0.11	1	0.09	7.3e-10	5.19	2.07e-07	0.58	FALSE
Liver	R3hcc1	alternative TSS	ENSRNOT00000101142	0.11	107	0.09	5.6e-10	-5.27	1.35e-07	0.7	FALSE
Liver	Pdlim2	gene expression	ENSRNOG00000008543	0.02	271	0.02	3.5e-03	-5.28	1.30e-07	0.45	FALSE
Liver	Ppp3cc	gene expression	ENSRNOG00000009745	0.02	1	0.01	8.0e-03	-5.31	1.10e-07	0.03	FALSE
Liver	Slc39a14	gene expression	ENSRNOG00000009832	0.03	611	0.03	5.2e-04	5.29	1.22e-07	0.58	FALSE
Liver	Polr3d	gene expression	ENSRNOG00000010028	0.08	97	0.06	5.6e-07	-5.31	1.09e-07	0.63	TRUE
Liver	Bmp1	gene expression	ENSRNOG00000010890	0.1	1	0.13	3.7e-14	5.28	1.30e-07	0.64	FALSE
Liver	Fgf17	gene expression	ENSRNOG00000012912	0.02	697	0.01	1.7e-02	-5.16	2.51e-07	0.47	FALSE
Liver	R3hcc1	gene expression	ENSRNOG00000016777	0.43	1	0.38	4.3e-44	-5.19	2.07e-07	0.58	FALSE
Liver	Rhobtb2	gene expression	ENSRNOG00000017373	0.04	1	0.03	1.8e-04	5.16	2.52e-07	0.06	FALSE
Liver	Tnfrsf10b	gene expression	ENSRNOG00000038483	0.05	1	0.03	1.3e-04	-5.27	1.37e-07	0.16	FALSE
Liver	ENSRNOG00000067366	gene expression	ENSRNOG00000067366	0.03	1	0.02	2.0e-03	-5.26	1.42e-07	0.07	FALSE
Liver	Sorbs3	intron excision ratio	chr15:45263517:45263631	0.03	478	0.02	1.5e-03	-5.34	9.55e-08	0.54	FALSE
Liver	Sorbs3	intron excision ratio	chr15:45263517:45264017	0.03	478	0.03	6.6e-04	5.33	9.58e-08	0.56	FALSE
Liver	Slc39a14	mRNA stability	ENSRNOG00000009832	0.02	611	0.02	4.0e-03	-5.28	1.26e-07	0.45	FALSE
Liver	R3hcc1	mRNA stability	ENSRNOG00000016777	0.11	107	0.09	2.8e-10	-5.27	1.35e-07	0.71	FALSE
Liver	Bin3	mRNA stability	ENSRNOG00000018023	0.17	61	0.16	6.5e-17	5.23	1.66e-07	0.59	FALSE
NAcc	Ppp3cc	gene expression	ENSRNOG00000009745	0.37	18	0.26	3.8e-19	5.31	1.10e-07	0.61	FALSE
NAcc	Nudt18	gene expression	ENSRNOG00000011831	0.16	7	0.06	2.1e-05	-5.23	1.65e-07	0.65	FALSE
NAcc	R3hcc1	gene expression	ENSRNOG00000016777	0.07	436	0.05	1.7e-04	5.28	1.28e-07	0.67	FALSE
NAcc	Rhobtb2	gene expression	ENSRNOG00000017373	0.11	430	0.07	5.7e-06	5.45	5.07e-08	0.66	FALSE
NAcc	Ccar2	gene expression	ENSRNOG00000018295	0.08	722	0.05	8.1e-05	5.29	1.20e-07	0.57	FALSE
NAcc	Tnfrsf10b	gene expression	ENSRNOG00000038483	0.12	1	0.07	3.2e-06	5.28	1.30e-07	0.57	FALSE
NAcc	Egr3	isoform ratio	ENSRNOT00000116948	0.06	709	0.03	4.1e-03	5.29	1.21e-07	0.51	FALSE
NAcc	Fhip2b	intron excision ratio	chr15:45658567:45658743	0.04	650	0	1.9e-01	-5.12	3.06e-07	0.4	FALSE
NAcc	ENSRNOG00000067974	intron excision ratio	chr15:44603231:44603574	0.04	330	0.01	4.4e-02	-5.31	1.11e-07	0.43	FALSE
NAcc	Ppp3cc	mRNA stability	ENSRNOG00000009745	0.06	639	0.03	1.9e-03	5.29	1.23e-07	0.58	FALSE
NAcc	R3hcc1	mRNA stability	ENSRNOG00000016777	0.04	61	0.03	1.6e-03	5.26	1.42e-07	0.43	FALSE
NAcc	Bin3	mRNA stability	ENSRNOG00000018023	0.04	1	0.04	4.6e-04	5.5	3.72e-08	0.07	FALSE
OFC	Ppp3cc	gene expression	ENSRNOG00000009745	0.45	1	0.15	1.8e-04	5.32	1.05e-07	0.13	FALSE
OFC	Polr3d	gene expression	ENSRNOG00000010028	0.26	1	0.12	9.0e-04	-5.27	1.33e-07	0.06	FALSE
OFC	Nudt18	gene expression	ENSRNOG00000011831	0.27	1	0.07	1.1e-02	-5.32	1.03e-07	0.06	FALSE
OFC	Dmtn	gene expression	ENSRNOG00000012273	0.14	1	0.07	7.8e-03	-5.32	1.03e-07	0.06	FALSE
OFC	Dok2	gene expression	ENSRNOG00000013922	0.15	1	0.08	7.1e-03	5.32	1.03e-07	0.06	FALSE
OFC	Rhobtb2	gene expression	ENSRNOG00000017373	0.25	1	0.12	7.9e-04	5.32	1.05e-07	0.06	FALSE
OFC	Ccar2	gene expression	ENSRNOG00000018295	0.26	721	0.13	5.1e-04	5.29	1.22e-07	0.47	FALSE
OFC	Tnfrsf10b	gene expression	ENSRNOG00000038483	0.23	1	0.08	7.0e-03	5.28	1.30e-07	0.06	FALSE
OFC	Dmtn	intron excision ratio	chr15:45679395:45679904	0.11	1	0.13	6.2e-04	5.24	1.64e-07	0.06	FALSE
OFC	Ppp3cc	mRNA stability	ENSRNOG00000009745	0.17	638	0.09	3.2e-03	5.29	1.22e-07	0.42	FALSE
OFC	Bin3	mRNA stability	ENSRNOG00000018023	0.27	4	0.14	3.2e-04	5.13	2.95e-07	0.52	FALSE
PL	Sorbs3	alternative TSS	ENSRNOT00000012056	0.04	711	0.02	1.9e-02	-5.29	1.23e-07	0.37	FALSE
PL	Sorbs3	alternative TSS	ENSRNOT00000113720	0.04	711	0.02	1.4e-02	5.29	1.23e-07	0.42	FALSE
PL	Ppp3cc	alternative TSS	ENSRNOT00000100817	0.07	1	0.04	6.1e-04	-5.32	1.03e-07	0.06	FALSE
PL	Ppp3cc	alternative TSS	ENSRNOT00000100817	0.09	1	0.07	6.7e-06	-5.32	1.03e-07	0.23	FALSE
PL	Dok2	alternative TSS	ENSRNOT00000103496	0.04	756	0.02	1.6e-02	-5.14	2.81e-07	0.49	FALSE
PL	Dok2	alternative TSS	ENSRNOT00000119823	0.04	756	0.01	2.2e-02	5.13	2.95e-07	0.46	FALSE
PL	Gfra2	alternative TSS	ENSRNOT00000096485	0.04	1	0.02	5.5e-03	-5.36	8.34e-08	0.05	FALSE
PL	Gfra2	alternative TSS	ENSRNOT00000019222	0.04	1	0.03	3.4e-03	5.36	8.34e-08	0.05	FALSE
PL	Gfra2	alternative TSS	ENSRNOT00000096485	0.04	1	0.02	6.3e-03	-5.36	8.34e-08	0.05	FALSE
PL	Ppp3cc	gene expression	ENSRNOG00000009745	0.55	408	0.41	1.1e-33	5.36	8.47e-08	0.61	FALSE
PL	Slc39a14	gene expression	ENSRNOG00000009832	0.11	1	0.08	1.5e-06	-5.29	1.21e-07	0.43	FALSE
PL	Polr3d	gene expression	ENSRNOG00000010028	0.06	588	0.04	4.6e-04	-5.28	1.27e-07	0.58	FALSE
PL	Lgi3	gene expression	ENSRNOG00000011323	0.05	645	0.04	4.1e-04	-5.28	1.33e-07	0.63	FALSE
PL	Dmtn	gene expression	ENSRNOG00000012273	0.13	25	0.13	6.1e-10	-5.21	1.91e-07	0.66	FALSE
PL	Entpd4	gene expression	ENSRNOG00000016321	0.06	118	0.03	2.0e-03	-5.25	1.49e-07	0.71	FALSE
PL	R3hcc1	gene expression	ENSRNOG00000016777	0.14	436	0.09	1.8e-07	5.28	1.28e-07	0.7	FALSE
PL	Rhobtb2	gene expression	ENSRNOG00000017373	0.34	1	0.26	1.4e-19	5.23	1.66e-07	0.58	FALSE
PL	Ccar2	gene expression	ENSRNOG00000018295	0.1	1	0.07	3.4e-06	5.3	1.16e-07	0.38	FALSE
PL	Tnfrsf10b	gene expression	ENSRNOG00000038483	0.09	1	0.07	9.3e-06	5.23	1.66e-07	0.18	FALSE
PL	Ppp3cc	intron excision ratio	chr15:45297492:45309209	0.05	1	0.03	2.0e-03	5.32	1.03e-07	0.04	FALSE
PL	Slc39a14	intron excision ratio	chr15:45403531:45423398	0.04	1	0.02	8.5e-03	-5.5	3.72e-08	0.04	FALSE
PL	Phyhip	intron excision ratio	chr15:45535048:45538056	0.04	1	0.01	4.2e-02	-5.32	1.03e-07	0.04	FALSE
PL	Dmtn	intron excision ratio	chr15:45702261:45704328	0.04	685	0.03	2.2e-03	5.2	1.96e-07	0.59	FALSE
PL	Ppp3cc	mRNA stability	ENSRNOG00000009745	0.21	639	0.14	4.3e-11	5.29	1.22e-07	0.61	FALSE
PL	Slc39a14	mRNA stability	ENSRNOG00000009832	0.04	1	0.03	2.3e-03	-5.5	3.72e-08	0.05	FALSE
PL	Bin3	mRNA stability	ENSRNOG00000018023	0.05	131	0.03	2.7e-03	5.32	1.02e-07	0.51	FALSE