Hub : Traits : Extensor digitorum longus weight : ← : →

chr4:146,441,482-149,011,707

Trait: Extensor digitorum longus weight

Best TWAS P=1.47e-09 · Best GWAS P=1.18e-09 conditioned to 1.44e-01

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Atg7	alternative polyA	ENSRNOT00000067532	0.02	1	0.02	2.2e-03	5.41	6.45e-08	0.03	FALSE
Adipose	Atg7	alternative polyA	ENSRNOT00000099380	0.04	1	0.04	1.0e-05	-5.41	6.45e-08	0.26	FALSE
Adipose	Atg7	alternative polyA	ENSRNOT00000067532	0.02	1	0.02	9.8e-04	5.41	6.45e-08	0.04	FALSE
Adipose	Atg7	alternative polyA	ENSRNOT00000099380	0.07	1	0.06	1.0e-06	-5.41	6.45e-08	0.32	FALSE
Adipose	Vgll4	gene expression	ENSRNOG00000007822	0.02	1519	0.01	1.1e-02	-5.84	5.34e-09	0.51	FALSE
Adipose	Tamm41	gene expression	ENSRNOG00000007874	0.28	208	0.27	1.8e-29	5.43	5.71e-08	0.06	FALSE
Adipose	Timp4	gene expression	ENSRNOG00000007955	0.05	27	0.04	2.1e-05	5.67	1.39e-08	0.61	FALSE
Adipose	Atg7	mRNA stability	ENSRNOG00000007486	0.04	1	0.04	4.3e-05	-5.68	1.33e-08	0.35	FALSE
Adipose	Tamm41	mRNA stability	ENSRNOG00000007874	0.19	1	0.17	2.5e-18	5.62	1.90e-08	0.61	FALSE
BLA	Atg7	alternative polyA	ENSRNOT00000096019	0.06	1953	0.02	2.2e-02	-5.13	2.94e-07	0.52	FALSE
BLA	Vgll4	gene expression	ENSRNOG00000007822	0.25	1519	0.16	5.6e-09	5.87	4.28e-09	0.7	FALSE
Brain	Atg7	alternative polyA	ENSRNOT00000096019	0.2	32	0.2	2.5e-18	-5.46	4.72e-08	0.67	FALSE
Brain	Atg7	alternative polyA	ENSRNOT00000109260	0.4	24	0.38	8.0e-37	5.7	1.20e-08	0.64	FALSE
Brain	Atg7	alternative polyA	ENSRNOT00000099380	0.16	1	0.19	6.3e-17	-5.62	1.90e-08	0.64	FALSE
Brain	Atg7	alternative polyA	ENSRNOT00000104390	0.08	1	0.05	8.5e-06	-5.64	1.73e-08	0.64	FALSE
Brain	Atg7	alternative polyA	ENSRNOT00000109260	0.34	303	0.36	1.4e-34	5.75	8.92e-09	0.65	FALSE
Brain	Vgll4	gene expression	ENSRNOG00000007822	0.15	1519	0.14	5.3e-13	5.54	3.04e-08	0.51	FALSE
Brain	Tamm41	gene expression	ENSRNOG00000007874	0.11	1461	0.1	2.7e-09	5.89	3.95e-09	0.71	FALSE
Brain	Atg7	isoform ratio	ENSRNOT00000067532	0.04	1	0.05	3.0e-05	-5.74	9.28e-09	0.44	FALSE
Brain	Atg7	isoform ratio	ENSRNOT00000104390	0.05	1	0.04	8.6e-05	-5.56	2.65e-08	0.33	FALSE
Brain	Atg7	isoform ratio	ENSRNOT00000109260	0.25	18	0.27	2.1e-25	5.69	1.27e-08	0.64	FALSE
Brain	Slc6a11	mRNA stability	ENSRNOG00000005697	0.06	1	0.04	7.9e-05	6.05	1.47e-09	0.86	TRUE
Eye	Atg7	isoform ratio	ENSRNOT00000067532	0.41	1953	0.05	6.4e-02	-5.85	5.03e-09	0.18	FALSE
IL	Atg7	alternative polyA	ENSRNOT00000096019	0.16	1	0.08	4.9e-03	-5.59	2.25e-08	0.06	FALSE
IL	Vgll4	gene expression	ENSRNOG00000007822	0.21	1518	0.12	8.4e-04	5.81	6.24e-09	0.51	FALSE
IL	Tamm41	gene expression	ENSRNOG00000007874	0.2	1460	0.08	7.1e-03	5.89	3.96e-09	0.54	FALSE
LHb	Atg7	alternative polyA	ENSRNOT00000109260	0.2	1950	0.09	3.7e-03	5.37	7.93e-08	0.31	FALSE
LHb	Atg7	alternative polyA	ENSRNOT00000109260	0.2	1950	0.09	3.2e-03	5.39	6.91e-08	0.31	FALSE
LHb	Vgll4	gene expression	ENSRNOG00000007822	0.25	1518	0.09	4.1e-03	5.68	1.33e-08	0.45	FALSE
LHb	Tamm41	gene expression	ENSRNOG00000007874	0.31	1460	0.13	5.2e-04	5.82	6.01e-09	0.55	FALSE
Liver	Atg7	alternative polyA	ENSRNOT00000109260	0.18	45	0.17	8.0e-19	5.64	1.68e-08	0.73	FALSE
Liver	Atg7	alternative polyA	ENSRNOT00000104390	0.03	1	0.02	8.9e-04	-5.62	1.96e-08	0.05	FALSE
Liver	Atg7	alternative polyA	ENSRNOT00000109260	0.2	43	0.2	3.6e-22	5.55	2.79e-08	0.71	FALSE
Liver	Atg7	gene expression	ENSRNOG00000007486	0.1	52	0.14	5.7e-15	-5.55	2.79e-08	0.72	FALSE
Liver	Vgll4	gene expression	ENSRNOG00000007822	0.05	1519	0.04	8.5e-06	5.89	3.94e-09	0.71	FALSE
Liver	Tamm41	gene expression	ENSRNOG00000007874	0.23	64	0.18	2.5e-19	5.8	6.75e-09	0.69	FALSE
Liver	Atg7	isoform ratio	ENSRNOT00000109260	0.09	104	0.09	6.6e-10	5.41	6.33e-08	0.23	FALSE
Liver	Tamm41	mRNA stability	ENSRNOG00000007874	0.04	1	0.03	2.8e-04	5.73	9.89e-09	0.16	FALSE
NAcc	Atg7	alternative polyA	ENSRNOT00000067532	0.08	1952	0.06	1.9e-05	-5.67	1.46e-08	0.51	FALSE
NAcc	Atg7	alternative polyA	ENSRNOT00000109260	0.15	1952	0.15	2.0e-11	5.76	8.31e-09	0.62	FALSE
NAcc	Atg7	alternative polyA	ENSRNOT00000067532	0.07	1952	0.05	2.3e-04	-5.77	7.77e-09	0.62	FALSE
NAcc	Atg7	alternative polyA	ENSRNOT00000099380	0.06	1952	0.04	6.8e-04	-5.5	3.75e-08	0.65	FALSE
NAcc	Atg7	alternative polyA	ENSRNOT00000109260	0.14	1952	0.14	2.4e-10	5.72	1.05e-08	0.59	FALSE
NAcc	Slc6a1	gene expression	ENSRNOG00000006527	0.04	2002	0.02	1.8e-02	5.43	5.62e-08	0.65	FALSE
NAcc	Vgll4	gene expression	ENSRNOG00000007822	0.32	231	0.29	3.8e-22	5.83	5.47e-09	0.62	FALSE
NAcc	Tamm41	gene expression	ENSRNOG00000007874	0.13	1460	0.08	1.1e-06	5.86	4.72e-09	0.73	FALSE
NAcc	Atp2b2	gene expression	ENSRNOG00000030269	0.07	31	0.03	3.6e-03	5.5	3.75e-08	0.21	FALSE
OFC	Atg7	alternative polyA	ENSRNOT00000109260	0.17	1	0.11	1.2e-03	5.59	2.29e-08	0.07	FALSE
OFC	Atg7	alternative polyA	ENSRNOT00000109260	0.17	1950	0.12	1.1e-03	5.54	2.99e-08	0.48	FALSE
OFC	Vgll4	gene expression	ENSRNOG00000007822	0.19	1	0.12	1.1e-03	5.61	2.07e-08	0.06	FALSE
OFC	Atg7	isoform ratio	ENSRNOT00000109260	0.14	1950	0.04	4.0e-02	5.47	4.44e-08	0.37	FALSE
PL	Atg7	alternative polyA	ENSRNOT00000067532	0.14	22	0.12	3.1e-09	-5.86	4.50e-09	0.71	FALSE
PL	Atg7	alternative polyA	ENSRNOT00000096019	0.11	1952	0.13	5.2e-10	-5.65	1.57e-08	0.66	FALSE
PL	Atg7	alternative polyA	ENSRNOT00000109260	0.33	1952	0.35	3.6e-27	5.87	4.39e-09	0.64	FALSE
PL	Atg7	alternative polyA	ENSRNOT00000067532	0.09	1952	0.09	3.2e-07	-5.77	8.08e-09	0.65	FALSE
PL	Atg7	alternative polyA	ENSRNOT00000099380	0.27	44	0.28	3.4e-21	-5.59	2.25e-08	0.64	FALSE
PL	Atg7	alternative polyA	ENSRNOT00000109260	0.28	37	0.32	3.8e-25	5.57	2.53e-08	0.64	FALSE
PL	Tamm41	gene expression	ENSRNOG00000007874	0.06	1460	0.02	1.8e-02	5.53	3.19e-08	0.42	FALSE
PL	Atg7	isoform ratio	ENSRNOT00000109260	0.18	1952	0.16	3.3e-12	5.71	1.11e-08	0.65	FALSE