Hub : Traits : Extensor digitorum longus weight : ← : →

chr2:225,862,840-228,461,478

Trait: Extensor digitorum longus weight

Best TWAS P=2.20e-11 · Best GWAS P=1.24e-12 conditioned to 7.62e-05

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Adh7	gene expression	Adh7	0.55	238	0.39	2.1e-45	-5.2	1.98e-07	0.36	FALSE
Adipose	Rap1gds1	gene expression	Rap1gds1	0.27	47	0.24	7.2e-26	5.83	5.69e-09	0.2	FALSE
Adipose	Rap1gds1	mRNA stability	Rap1gds1	0.12	107	0.1	1.3e-11	-6	2.01e-09	0.37	FALSE
BLA	RGD1309170	gene expression	RGD1309170	0.12	25	0.06	5.1e-04	5.22	1.83e-07	0.23	FALSE
BLA	Tspan5	gene expression	Tspan5	0.51	16	0.28	2.8e-15	5.23	1.74e-07	0.14	FALSE
Brain	Rap1gds1	gene expression	Rap1gds1	0.42	163	0.5	1.8e-52	-5.91	3.49e-09	0.75	FALSE
Brain	Tspan5	gene expression	Tspan5	0.7	478	0.48	1.7e-50	-5.34	9.38e-08	0.07	FALSE
Brain	Tspan5	isoform ratio	XM_039102726.1	0.15	7	0.14	4.3e-13	-5.38	7.55e-08	0.83	FALSE
Eye	LOC102547266	gene expression	LOC102547266	0.44	118	0.14	3.4e-03	-5.68	1.32e-08	0.33	FALSE
IL	Tspan5	gene expression	Tspan5	0.52	1	0.2	1.7e-05	-5.8	6.57e-09	0.09	FALSE
LHb	Tspan5	alternative polyA	NM_001004090.2	0.32	1	0.16	1.5e-04	6.01	1.88e-09	0.08	FALSE
LHb	Tspan5	alternative polyA	XM_039102726.1	0.39	1	0.17	7.3e-05	-6.01	1.88e-09	0.1	FALSE
LHb	Stpg2	gene expression	Stpg2	0.2	2595	0.14	3.5e-04	5.81	6.14e-09	0.25	FALSE
LHb	Tspan5	gene expression	Tspan5	0.38	3	0.26	6.2e-07	5.63	1.85e-08	0.13	FALSE
LHb	Tspan5	isoform ratio	NM_001004090.2	0.69	1	0.24	2.0e-06	6.01	1.88e-09	0.17	FALSE
LHb	Tspan5	isoform ratio	XM_039102726.1	0.64	111	0.22	6.9e-06	-6.33	2.45e-10	0.75	FALSE
Liver	Rap1gds1	gene expression	Rap1gds1	0.25	12	0.24	7.3e-27	6.28	3.48e-10	0.21	FALSE
Liver	Tspan5	gene expression	Tspan5	0.04	4	0.01	1.8e-02	6.46	1.07e-10	0.5	FALSE
NAcc	Tspan5	alternative polyA	NM_001004090.2	0.1	1	0.11	3.2e-12	6.07	1.28e-09	0.64	FALSE
NAcc	Tspan5	alternative polyA	XM_039102726.1	0.1	1	0.1	1.9e-11	-6.02	1.71e-09	0.58	FALSE
NAcc	Rap1gds1	gene expression	Rap1gds1	0.07	6	0.09	3.1e-10	5.58	2.46e-08	0.34	FALSE
NAcc	Tspan5	isoform ratio	NM_001004090.2	0.07	1	0.07	1.3e-08	6.02	1.71e-09	0.57	FALSE
NAcc	Tspan5	isoform ratio	XM_039102726.1	0.07	1	0.08	1.3e-09	-6.02	1.71e-09	0.57	FALSE
OFC	LOC102555623	alternative TSS	XR_005501334.1	0.24	3815	0.06	1.5e-02	-6.09	1.15e-09	0.54	FALSE
OFC	Rap1gds1	gene expression	Rap1gds1	0.19	1	0.12	7.9e-04	-6.49	8.53e-11	0.06	FALSE
OFC	Tspan5	gene expression	Tspan5	0.46	111	0.26	7.1e-07	-5.47	4.39e-08	0.38	FALSE
OFC	Rap1gds1	mRNA stability	Rap1gds1	0.17	1	0.08	5.8e-03	-6.34	2.28e-10	0.05	FALSE
PL	LOC102547266	alternative polyA	XR_005501341.1	0.06	3227	0.03	3.4e-04	5.2	1.96e-07	0.75	FALSE
PL	Tspan5	alternative polyA	NM_001004090.2	0.08	1	0.04	5.9e-05	6.05	1.44e-09	0.57	FALSE
PL	Tspan5	alternative polyA	XM_039102726.1	0.08	1	0.03	3.7e-04	-6.05	1.44e-09	0.42	FALSE
PL	Rap1gds1	gene expression	Rap1gds1	0.18	37	0.24	4.3e-26	-6.26	3.88e-10	0.52	FALSE
PL	Tspan5	gene expression	Tspan5	0.55	87	0.31	3.5e-35	-5.31	1.09e-07	0.07	FALSE
PL	LOC102547266	isoform ratio	XR_005501343.1	0.06	7	0.06	8.5e-07	-5.39	7.04e-08	0.56	FALSE
PL	Tspan5	isoform ratio	NM_001004090.2	0.1	1	0.07	6.9e-08	6.07	1.28e-09	0.64	FALSE
PL	Tspan5	isoform ratio	XM_039102726.1	0.1	1	0.08	6.5e-09	-6.07	1.28e-09	0.64	FALSE
PL	Rap1gds1	mRNA stability	Rap1gds1	0.07	18	0.06	1.4e-07	-5.74	9.29e-09	0.58	FALSE
PL	Tspan5	mRNA stability	Tspan5	0.05	3201	0.04	9.9e-05	5.23	1.70e-07	0.52	FALSE
pVTA	Tspan5	alternative polyA	NM_001004090.2	0.13	1	0.11	1.6e-05	5.48	4.36e-08	0.04	FALSE
pVTA	Tspan5	alternative polyA	XM_039102726.1	0.13	1	0.1	6.9e-05	-5.48	4.16e-08	0.04	FALSE
pVTA	Rap1gds1	gene expression	Rap1gds1	0.11	1	0.11	1.3e-05	-6.69	2.20e-11	0.76	TRUE
pVTA	Tspan5	isoform ratio	XM_039102726.1	0.13	10	0.07	4.8e-04	5.51	3.61e-08	0.28	FALSE
pVTA	LOC102547266	intron excision ratio	chr2_227257635_227259114	0.11	1	0.06	1.3e-03	-5.93	3.10e-09	0.06	FALSE