Hub : Traits : Extensor digitorum longus weight : ← : →

chr2:99,427,434-102,500,927

Trait: Extensor digitorum longus weight

Best TWAS P=2.28e-08 · Best GWAS P=1.14e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Pde7a	mRNA stability	Pde7a	0.17	1	0.1	3.6e-11	5.32	1.04e-07	0.71	FALSE
BLA	Cyp7b1	gene expression	Cyp7b1	0.46	9	0.25	7.3e-14	5.36	8.41e-08	0.41	FALSE
Brain	Bhlhe22	gene expression	Bhlhe22	0.08	1	0.04	3.1e-04	5.31	1.08e-07	0.06	FALSE
Brain	Cyp7b1	gene expression	Cyp7b1	0.3	1	0.2	1.6e-18	-5.23	1.70e-07	0.15	FALSE
Brain	Pde7a	gene expression	Pde7a	0.05	1	0.03	1.1e-03	5.21	1.85e-07	0.04	FALSE
Brain	Cyp7b1	mRNA stability	Cyp7b1	0.07	1	0.03	3.7e-04	-5.31	1.09e-07	0.05	FALSE
LHb	Armc1	gene expression	Armc1	0.31	15	0.09	4.0e-03	-5.39	7.23e-08	0.5	FALSE
NAcc	Armc1	gene expression	Armc1	0.14	1	0.05	3.3e-06	5.32	1.04e-07	0.58	FALSE
NAcc	Bhlhe22	gene expression	Bhlhe22	0.11	1	0.1	1.7e-11	-5.2	2.03e-07	0.15	FALSE
NAcc	Cyp7b1	gene expression	Cyp7b1	0.11	45	0.1	1.2e-11	-5.29	1.21e-07	0.23	FALSE
NAcc	Cyp7b1	mRNA stability	Cyp7b1	0.03	2246	0.02	1.8e-03	5.52	3.32e-08	0.33	FALSE
PL	Cyp7b1	alternative polyA	XM_039101794.1	0.03	2246	0.01	1.1e-02	-5.42	5.83e-08	0.33	FALSE
PL	Cyp7b1	gene expression	Cyp7b1	0.13	2246	0.1	1.3e-10	5.59	2.28e-08	0.45	TRUE
PL	LOC120100778	gene expression	LOC120100778	0.02	1	0	2.6e-01	-5.47	4.49e-08	0.03	FALSE
PL	Cyp7b1	intron excision ratio	chr2_100638373_100669465	0.1	60	0.06	3.1e-07	-5.55	2.91e-08	0.34	FALSE
PL	Cyp7b1	intron excision ratio	chr2_100660904_100669465	0.08	24	0.04	1.6e-05	-5.48	4.25e-08	0.35	TRUE