Hub : Traits : Extensor digitorum longus weight : ← : →

chr2:228,337,782-231,132,460

Trait: Extensor digitorum longus weight

Best TWAS P = 1.12e-11 · Best GWAS P= 6.18e-14 conditioned to 7.22e-05

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Dnajb14	gene expression	Dnajb14	0.23	227	0.23	4.4e-25	5.74	9.60e-09	0.13	FALSE
Adipose	Rap1gds1	gene expression	Rap1gds1	0.25	1	0.21	2.4e-23	-6.24	4.35e-10	0.18	FALSE
Adipose	Stpg2	gene expression	Stpg2	0.13	1	0.13	2.3e-14	-6.79	1.12e-11	0.34	TRUE
Adipose	Rap1gds1	mRNA stability	Rap1gds1	0.12	156	0.1	3.7e-11	-5.83	5.40e-09	0.28	FALSE
BLA	Rap1gds1	alternative TSS	XM_039102477.2	0.12	63	0.04	2.2e-03	-5.48	4.25e-08	0.17	FALSE
BLA	Tspan5	gene expression	Tspan5	0.63	13	0.27	8.1e-15	5.46	4.80e-08	0.15	FALSE
Brain	Rap1gds1	gene expression	Rap1gds1	0.42	78	0.5	6.7e-53	-5.8	6.73e-09	0.58	FALSE
Brain	Stpg2	gene expression	Stpg2	0.05	1	0.06	6.2e-06	-6.24	4.35e-10	0.02	FALSE
Brain	Tspan5	gene expression	Tspan5	0.67	48	0.5	9.3e-53	-5.58	2.34e-08	0.05	FALSE
Brain	LOC120100955	mRNA stability	LOC120100955	0.03	1	0.04	4.7e-05	5.92	3.16e-09	0.04	FALSE
Eye	LOC102547266	gene expression	LOC102547266	0.6	27	0.13	4.5e-03	-5.58	2.37e-08	0.23	FALSE
IC	Rap1gds1	gene expression	Rap1gds1	0.45	55	0.22	1.2e-09	-5.68	1.36e-08	0.45	FALSE
IC	Tspan5	gene expression	Tspan5	0.56	7	0.38	6.2e-17	5.86	4.54e-09	0.19	FALSE
IC	Tspan5	isoform ratio	NM_001004090.2	0.17	12	0.09	1.5e-04	5.35	8.57e-08	0.55	FALSE
IC	Tspan5	isoform ratio	XM_039102726.2	0.17	9	0.07	5.2e-04	-5.34	9.40e-08	0.56	FALSE
LHb	Tspan5	gene expression	Tspan5	0.41	55	0.24	2.3e-06	-5.47	4.41e-08	0.12	FALSE
Liver	Rap1gds1	gene expression	Rap1gds1	0.25	1	0.24	9.8e-27	-6.16	7.19e-10	0.12	FALSE
Liver	Trmt10a	gene expression	Trmt10a	0.08	3818	0.04	1.1e-05	5.21	1.88e-07	0.37	FALSE
Liver	Tspan5	gene expression	Tspan5	0.05	1	0.03	5.0e-04	-5.87	4.35e-09	0.04	FALSE
Liver	LOC120100951	isoform ratio	XR_005501330.2	0.18	4040	0.11	4.0e-12	-5.65	1.60e-08	0.47	FALSE
NAcc	Rap1gds1	gene expression	Rap1gds1	0.07	11	0.07	1.7e-11	5.48	4.30e-08	0.09	FALSE
NAcc	Eif4e	isoform ratio	XM_063281174.1	0.04	4	0.03	8.6e-05	-5.5	3.84e-08	0.41	FALSE
OFC	Rap1gds1	gene expression	Rap1gds1	0.23	1	0.14	3.4e-04	-6.63	3.27e-11	0.07	FALSE
OFC	Tspan5	gene expression	Tspan5	0.45	1	0.27	3.6e-07	-5.49	3.96e-08	0.04	FALSE
OFC	Tspan5	isoform ratio	NM_001004090.2	0.23	1	0.09	3.4e-03	5.85	4.87e-09	0.05	FALSE
OFC	Tspan5	isoform ratio	XM_039102726.2	0.24	1	0.09	3.3e-03	-5.85	4.87e-09	0.05	FALSE
PL	Tspan5	alternative TSS	NM_001004090.2	0.05	3306	0.02	2.3e-03	5.48	4.18e-08	0.5	FALSE
PL	Rap1gds1	gene expression	Rap1gds1	0.17	2556	0.23	1.0e-24	6.31	2.87e-10	0.4	FALSE
PL	Tspan5	gene expression	Tspan5	0.56	39	0.33	6.9e-37	5.36	8.41e-08	0.04	FALSE
PL	Tspan5	isoform ratio	NM_001004090.2	0.24	44	0.17	4.7e-18	5.59	2.30e-08	0.12	FALSE
PL	Tspan5	isoform ratio	XM_039102726.2	0.24	44	0.17	5.9e-18	-5.59	2.25e-08	0.13	FALSE
PL	Rap1gds1	mRNA stability	Rap1gds1	0.06	2556	0.06	1.6e-07	5.38	7.32e-08	0.46	FALSE
pVTA	Rap1gds1	gene expression	Rap1gds1	0.15	1	0.17	1.5e-13	-6.77	1.25e-11	0.87	FALSE
pVTA	LOC102547266	intron excision ratio	chr2_229931002_229932481	0.1	1	0.1	2.5e-08	-6.06	1.36e-09	0.51	FALSE
pVTA	Rap1gds1	mRNA stability	Rap1gds1	0.06	1	0.06	1.6e-05	-6.29	3.25e-10	0.07	FALSE
RMTg	Rap1gds1	gene expression	Rap1gds1	0.12	1	0.12	4.5e-04	-6.27	3.72e-10	0.05	FALSE
RMTg	Stpg2	isoform ratio	XM_017591047.3	0.16	2564	0.11	6.4e-04	-5.26	1.48e-07	0.09	FALSE