Hub : Traits : Extensor digitorum longus weight : ← : →

chr2:99,787,494-102,500,927

Trait: Extensor digitorum longus weight

Best TWAS P=1.87e-08 · Best GWAS P=1.14e-08 conditioned to 1.16e-01

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
BLA	Cyp7b1	gene expression	ENSRNOG00000009730	0.43	71	0.29	5.8e-16	5.55	2.93e-08	0.49	FALSE
Brain	Cyp7b1	gene expression	ENSRNOG00000009730	0.32	271	0.28	7.1e-26	5.34	9.31e-08	0.21	FALSE
Brain	Pde7a	gene expression	ENSRNOG00000013048	0.03	1	0.03	3.9e-04	-5.21	1.85e-07	0.05	FALSE
Brain	Bhlhe22	gene expression	ENSRNOG00000021745	0.07	1	0.04	8.5e-05	-5.15	2.54e-07	0.05	FALSE
Brain	Cyp7b1	intron excision ratio	chr2:100638373:100669465	0.04	17	0.04	2.6e-04	5.62	1.87e-08	0.35	TRUE
Brain	Cyp7b1	intron excision ratio	chr2:100660904:100669465	0.04	17	0.04	1.1e-04	-5.48	4.31e-08	0.35	FALSE
Brain	Cyp7b1	mRNA stability	ENSRNOG00000009730	0.05	1	0.03	7.4e-04	5.31	1.09e-07	0.04	FALSE
IL	Cyp7b1	gene expression	ENSRNOG00000009730	0.18	1	0.08	6.5e-03	5.3	1.14e-07	0.05	FALSE
LHb	Armc1	gene expression	ENSRNOG00000013253	0.31	1	0.2	1.4e-05	-5.43	5.52e-08	0.09	FALSE
Liver	ENSRNOG00000066523	mRNA stability	ENSRNOG00000066523	0.48	2080	0.3	1.6e-33	5.56	2.69e-08	0.53	FALSE
NAcc	Mtfr1	gene expression	ENSRNOG00000021359	0.06	1	0.04	3.3e-04	-5.45	4.95e-08	0.08	FALSE
NAcc	Bhlhe22	gene expression	ENSRNOG00000021745	0.11	1	0.07	6.0e-06	5.23	1.70e-07	0.09	FALSE
PL	Cyp7b1	gene expression	ENSRNOG00000009730	0.1	2233	0.07	3.9e-06	5.5	3.75e-08	0.41	FALSE
PL	Armc1	gene expression	ENSRNOG00000013253	0.06	1	0.04	5.1e-04	-5.33	9.68e-08	0.08	FALSE