Hub : Traits : Extensor digitorum longus weight : ← : →

chr10:58,773,413-61,500,745

Trait: Extensor digitorum longus weight

Best TWAS P=2.72e-08 · Best GWAS P=2.35e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Sgsm2	gene expression	ENSRNOG00000027194	0.12	37	0.11	7.4e-12	-5.42	5.96e-08	0.66	FALSE
Adipose	ENSRNOG00000064121	gene expression	ENSRNOG00000064121	0.14	1	0.03	5.4e-04	5.5	3.89e-08	0.14	FALSE
Adipose	Scarf1	isoform ratio	ENSRNOT00000088722	0.04	1	0.03	3.2e-04	5.48	4.31e-08	0.1	FALSE
Adipose	Scarf1	isoform ratio	ENSRNOT00000104013	0.04	1	0.02	1.1e-03	-5.48	4.31e-08	0.1	FALSE
Adipose	Myo1c	intron excision ratio	chr10:60499487:60505081	0.07	1	0.03	7.3e-04	5.5	3.91e-08	0.19	FALSE
Adipose	Sgsm2	mRNA stability	ENSRNOG00000027194	0.03	820	0.01	1.6e-02	-5.25	1.49e-07	0.62	FALSE
BLA	Rtn4rl1	gene expression	ENSRNOG00000003121	0.17	1	0.12	4.0e-07	5.33	9.63e-08	0.48	FALSE
BLA	Inpp5k	gene expression	ENSRNOG00000056954	0.25	1	0.22	3.5e-12	5.49	4.05e-08	0.8	FALSE
BLA	Smyd4	intron excision ratio	chr10:60200371:60201453	0.08	1	0.07	1.7e-04	-5.5	3.91e-08	0.16	FALSE
Brain	Rtn4rl1	gene expression	ENSRNOG00000003121	0.2	755	0.15	3.4e-14	5.34	9.22e-08	0.78	FALSE
Brain	Crk	gene expression	ENSRNOG00000025792	0.33	30	0.23	4.9e-21	5.56	2.72e-08	0.83	TRUE
Brain	Doc2b	gene expression	ENSRNOG00000060054	0.8	93	0.52	5.6e-56	5.23	1.66e-07	0.85	FALSE
Brain	Doc2b	intron excision ratio	chr10:60633027:60636786	0.25	1275	0.09	2.0e-08	-5.16	2.41e-07	0.82	FALSE
Brain	Myo1c	mRNA stability	ENSRNOG00000004072	0.06	1	0.04	1.6e-04	-5.51	3.59e-08	0.23	FALSE
IL	Rap1gap2	gene expression	ENSRNOG00000002652	0.85	1	0.41	7.1e-11	5.32	1.06e-07	0.87	FALSE
LHb	Crk	gene expression	ENSRNOG00000025792	0.25	1	0.17	8.3e-05	5.51	3.59e-08	0.09	FALSE
Liver	Rpa1	gene expression	ENSRNOG00000003123	0.13	812	0.1	1.1e-10	5.52	3.30e-08	0.78	FALSE
Liver	Crk	gene expression	ENSRNOG00000025792	0.05	1	0.03	7.4e-04	5.5	3.91e-08	0.11	FALSE
Liver	Slc43a2	intron excision ratio	chr10:60411108:60413539	0.03	1	0.02	6.0e-03	-5.52	3.38e-08	0.05	FALSE
Liver	Serpinf1	mRNA stability	ENSRNOG00000003172	0.04	1	0.02	2.2e-03	-5.47	4.58e-08	0.06	FALSE
NAcc	Crk	gene expression	ENSRNOG00000025792	0.23	4	0.18	3.0e-13	5.21	1.89e-07	0.77	FALSE
NAcc	Doc2b	gene expression	ENSRNOG00000060054	0.4	42	0.36	6.3e-28	5.53	3.23e-08	0.84	FALSE
OFC	Crk	gene expression	ENSRNOG00000025792	0.24	1	0.19	2.2e-05	5.47	4.61e-08	0.1	FALSE
OFC	Doc2b	gene expression	ENSRNOG00000060054	0.46	5	0.1	2.0e-03	5.28	1.27e-07	0.56	FALSE
OFC	Rph3al	gene expression	ENSRNOG00000061429	0.4	1	0.28	2.7e-07	5.51	3.59e-08	0.66	FALSE
OFC	ENSRNOG00000068527	gene expression	ENSRNOG00000068527	0.19	1	0.16	1.1e-04	-5.5	3.90e-08	0.15	FALSE
OFC	Rph3al	mRNA stability	ENSRNOG00000061429	0.27	1	0.18	5.4e-05	5.51	3.59e-08	0.16	FALSE
PL	Rtn4rl1	gene expression	ENSRNOG00000003121	0.11	1	0.11	1.0e-08	5.43	5.62e-08	0.73	FALSE
PL	Rpa1	gene expression	ENSRNOG00000003123	0.07	1	0.04	2.3e-04	5.49	3.98e-08	0.15	FALSE
PL	Crk	gene expression	ENSRNOG00000025792	0.15	1	0.11	1.3e-08	5.5	3.89e-08	0.82	FALSE
PL	Doc2b	gene expression	ENSRNOG00000060054	0.25	1	0.13	2.3e-10	5.53	3.19e-08	0.87	FALSE
PL	ENSRNOG00000068527	gene expression	ENSRNOG00000068527	0.09	1	0.09	3.7e-07	-5.26	1.44e-07	0.66	FALSE
PL	Myo1c	mRNA stability	ENSRNOG00000004072	0.04	1	0.02	1.0e-02	-5.47	4.58e-08	0.04	FALSE