Best TWAS P=2.565357e-20 · Best GWAS P=8.487523e-05 conditioned to 1.337624e-46
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | BLA | Syt5 | mRNA stability | ENSRNOG00000018217 | 0.06 | 0 | enet | 782 | 0.01 | 0.16 | -1.6 | 9.2 | 2.6e-20 | 0.69 | 0.28 | 0.21 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.