Hub : Traits : Delay discounting time to switch 0 sec :

chr6:68,065,049-70,118,374

Trait: Delay discounting time to switch 0 sec

Best TWAS P=3.808106e-08 · Best GWAS P=1.065656e-06 conditioned to 0.2229532

Associated models

# Tissue Gene Modality RNA phenotype h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 BLA G2e3 gene expression ENSRNOG00000004232 0.12 0.03 blup 1570 0.06 6.3e-04 4.6 -5.3 9.8e-08 0.68 0.35 0.63 FALSE
2 BLA Hectd1 gene expression ENSRNOG00000006905 0.06 0.00 blup 1835 0.04 3.9e-03 4.7 -5.3 1.0e-07 0.76 0.43 0.39 FALSE
3 BLA Scfd1 mRNA stability ENSRNOG00000031203 0.33 0.23 lasso 6 0.23 8.6e-13 -4.4 5.2 2.4e-07 -0.83 0.67 0.33 FALSE
4 Brain Hectd1 mRNA stability ENSRNOG00000006905 0.05 0.00 blup 1835 0.02 4.8e-03 -3.8 -5.3 1.4e-07 0.78 0.44 0.38 FALSE
5 LHb Heatr5a gene expression ENSRNOG00000006483 0.18 0.14 blup 1750 0.14 3.7e-04 4.6 -5.2 2.0e-07 0.63 0.38 0.50 FALSE
6 Liver Scfd1 mRNA stability ENSRNOG00000031203 0.10 0.06 blup 1615 0.06 5.3e-07 -4.4 -5.1 2.9e-07 0.95 0.55 0.45 FALSE
7 NAcc G2e3 gene expression ENSRNOG00000004232 0.12 0.09 lasso 13 0.10 8.0e-08 4.8 -5.5 3.8e-08 0.74 0.35 0.65 TRUE
8 NAcc Hectd1 intron excision ratio chr6:69206174:69209504 0.04 0.03 blup 1833 0.03 1.6e-03 4.6 -5.1 3.1e-07 0.62 0.42 0.47 FALSE
9 OFC G2e3 gene expression ENSRNOG00000004232 0.55 0.13 lasso 5 0.17 8.2e-05 -4.8 -5.4 6.1e-08 0.88 0.31 0.52 FALSE
10 PL G2e3 gene expression ENSRNOG00000004232 0.23 0.13 blup 1569 0.21 1.2e-15 4.7 -5.4 6.7e-08 0.75 0.35 0.65 FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.