Best TWAS P=5.89e-09 · Best GWAS P=6.19e-07 conditioned to 6.51e-01
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PL | Crtc3 | mRNA stability | Crtc3 | 0.02 | 22 | 0.01 | 2.9e-02 | 5.71 | 1.14e-08 | 0.45 | FALSE |
| PL | Hddc3 | mRNA stability | Hddc3 | 0.03 | 58 | 0.02 | 1.9e-03 | -5.82 | 5.89e-09 | 0.69 | TRUE |
| pVTA | Kif7 | gene expression | Kif7 | 0.21 | 30 | 0.13 | 3.5e-06 | 5.44 | 5.21e-08 | 0.48 | FALSE |
| pVTA | Ngrn | isoform ratio | NR_028055.1 | 0.11 | 1939 | 0.05 | 3.3e-03 | 5.28 | 1.31e-07 | 0.34 | FALSE |