Best TWAS P = 3.83e-09 · Best GWAS P= 7.31e-10 conditioned to 1.00e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Arrdc4 | gene expression | Arrdc4 | 0.1 | 19 | 0.16 | 5.8e-17 | 5.89 | 3.83e-09 | 0.4 | TRUE |
| Adipose | Arrdc4 | mRNA stability | Arrdc4 | 0.02 | 1 | 0.02 | 1.3e-03 | 5.73 | 1.01e-08 | 0.03 | FALSE |
| BLA | Arrdc4 | gene expression | Arrdc4 | 0.05 | 1681 | 0.04 | 4.1e-03 | 5.71 | 1.11e-08 | 0.45 | FALSE |
| Liver | Arrdc4 | gene expression | Arrdc4 | 0.02 | 3 | 0.02 | 4.4e-03 | -5.86 | 4.69e-09 | 0.35 | TRUE |
| NAcc | Arrdc4 | gene expression | Arrdc4 | 0.04 | 1 | 0.04 | 4.2e-07 | 5.5 | 3.81e-08 | 0.07 | FALSE |