Best TWAS P=9.56e-08 · Best GWAS P=6.19e-07 conditioned to 4.55e-01
Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
---|---|---|---|---|---|---|---|---|---|---|---|
IL | Gdpgp1 | intron excision ratio | chr1:134189891:134190619 | 0.12 | 4 | 0.08 | 5.6e-03 | 5.11 | 3.15e-07 | 0.18 | FALSE |
LHb | Idh2 | isoform ratio | ENSRNOT00000019059 | 0.21 | 7 | 0.06 | 1.7e-02 | 5.33 | 9.56e-08 | 0.28 | TRUE |
NAcc | Idh2 | alternative polyA | ENSRNOT00000114588 | 0.09 | 59 | 0.11 | 3.1e-08 | 5.2 | 2.03e-07 | 0.33 | FALSE |