chr1:238,391,248-240,123,287

Trait: Se content in liver

Best TWAS P=7.35e-08 · Best GWAS P=1.03e-07 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Tctn3 gene expression ENSRNOG00000062728 0.11 1 0.07 2.7e-08 5.16 2.45e-07 0.51 FALSE
Adipose Sorbs1 intron excision ratio chr1:239171438:239176063 0.15 20 0.12 2.8e-13 -5.11 3.20e-07 0.44 FALSE
Adipose Sorbs1 intron excision ratio chr1:239171438:239182421 0.16 20 0.16 4.9e-17 5.11 3.20e-07 0.44 FALSE
Adipose Sorbs1 intron excision ratio chr1:239184817:239189712 0.08 1 0.05 3.4e-06 5.16 2.43e-07 0.31 FALSE
Adipose Sorbs1 intron excision ratio chr1:239189741:239193373 0.03 1 0.02 2.8e-03 -5.16 2.43e-07 0.03 FALSE
Adipose Sorbs1 intron excision ratio chr1:239193514:239203110 0.13 1 0.12 2.8e-13 -5.11 3.20e-07 0.4 FALSE
Adipose Sorbs1 intron excision ratio chr1:239197213:239197853 0.18 26 0.13 2.0e-14 5.11 3.20e-07 0.45 FALSE
Adipose Sorbs1 intron excision ratio chr1:239197213:239203110 0.07 1 0.04 5.9e-05 -5.11 3.20e-07 0.27 FALSE
BLA Tctn3 gene expression ENSRNOG00000062728 0.26 31 0.25 9.4e-14 5.21 1.85e-07 0.48 FALSE
Brain Entpd1 alternative TSS ENSRNOT00000019751 0.03 1 0.02 4.2e-03 -5.25 1.52e-07 0.04 FALSE
Brain Entpd1 alternative TSS ENSRNOT00000115487 0.03 1 0.02 5.6e-03 5.25 1.52e-07 0.04 FALSE
Brain Pdlim1 gene expression ENSRNOG00000016166 0.12 1 0.13 2.3e-12 5.32 1.03e-07 0.62 FALSE
Brain Aldh18a1 gene expression ENSRNOG00000067262 0.05 1 0.08 1.0e-07 -5.19 2.05e-07 0.5 FALSE
Brain Sorbs1 intron excision ratio chr1:239184817:239189712 0.07 5 0.11 2.7e-10 5.29 1.24e-07 0.42 TRUE
Brain Sorbs1 intron excision ratio chr1:239184817:239193373 0.08 74 0.11 3.0e-10 -5.29 1.25e-07 0.39 FALSE
Brain Sorbs1 intron excision ratio chr1:239189741:239193373 0.02 1 0.01 2.8e-02 5.16 2.43e-07 0.04 FALSE
Brain Sorbs1 intron excision ratio chr1:239193514:239196842 0.07 2347 0.05 2.8e-05 5.2 2.01e-07 0.4 FALSE
Brain Sorbs1 intron excision ratio chr1:239193514:239203110 0.14 1 0.18 2.5e-16 -5.14 2.74e-07 0.43 FALSE
Brain Sorbs1 intron excision ratio chr1:239197213:239203110 0.1 2347 0.09 5.1e-09 5.32 1.04e-07 0.37 TRUE
LHb Tctn3 gene expression ENSRNOG00000062728 0.24 2 0.21 8.9e-06 5.15 2.56e-07 0.44 FALSE
LHb Sorbs1 intron excision ratio chr1:239171438:239182421 0.23 2337 0 2.9e-01 5.11 3.14e-07 0.24 FALSE
Liver Tctn3 gene expression ENSRNOG00000062728 0.03 1 0.01 3.3e-02 5.14 2.75e-07 0.03 FALSE
Liver Sorbs1 intron excision ratio chr1:239171438:239176063 0.05 1 0.04 1.6e-05 -5.11 3.20e-07 0.26 FALSE
NAcc Entpd1 alternative TSS ENSRNOT00000019751 0.1 16 0.1 5.2e-08 -5.35 8.56e-08 0.5 FALSE
NAcc Entpd1 alternative TSS ENSRNOT00000115487 0.11 13 0.11 2.0e-08 5.38 7.35e-08 0.5 TRUE
NAcc Entpd1 gene expression ENSRNOG00000014574 0.42 53 0.48 2.8e-40 -5.36 8.31e-08 0.48 FALSE
NAcc Aldh18a1 gene expression ENSRNOG00000067262 0.03 1 0.02 9.4e-03 -5.19 2.05e-07 0.04 FALSE
NAcc Entpd1 intron excision ratio chr1:239473951:239521887 0.03 1 0.04 1.1e-03 -5.1 3.40e-07 0.04 FALSE
NAcc Sorbs1 intron excision ratio chr1:239128876:239130234 0.04 1 0.06 3.6e-05 -5.13 2.90e-07 0.14 FALSE
NAcc Sorbs1 intron excision ratio chr1:239184817:239193373 0.06 2344 0.06 4.5e-05 -5.15 2.64e-07 0.36 FALSE
OFC Entpd1 gene expression ENSRNOG00000014574 0.23 4 0.19 3.0e-05 -5.16 2.49e-07 0.45 FALSE
PL Tctn3 gene expression ENSRNOG00000062728 0.14 1 0.14 1.1e-10 5.1 3.40e-07 0.44 FALSE
PL Aldh18a1 gene expression ENSRNOG00000067262 0.04 1 0.04 1.1e-03 -5.16 2.43e-07 0.04 TRUE
PL Sorbs1 intron excision ratio chr1:239184817:239193373 0.04 2344 0.06 4.0e-05 -5.17 2.29e-07 0.38 FALSE