Hub : Traits : Total locomotion distance, NPP test : ← : →

chr1:140,510,980-142,727,457

Trait: Total locomotion distance, NPP test

Best TWAS P = 4.67e-17 · Best GWAS P= 1.73e-17 conditioned to NaN

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Ctsc	alternative polyA	NM_017097.2	0.17	1	0.18	7.5e-20	-5.31	1.10e-07	0	TRUE
Adipose	Ctsc	alternative polyA	XM_008759637.3	0.19	1	0.19	5.0e-21	5.31	1.10e-07	0	FALSE
Adipose	LOC102554680	gene expression	LOC102554680	0.07	1	0.06	1.3e-07	5.25	1.49e-07	0	FALSE
Adipose	Ctsc	isoform ratio	NM_017097.2	0.18	2521	0.16	5.6e-17	6.73	1.71e-11	0	FALSE
Adipose	Ctsc	isoform ratio	XM_008759637.3	0.19	2521	0.16	1.2e-17	-6.67	2.53e-11	0	FALSE
Adipose	Ctsc	intron excision ratio	chr1_142031177_142036233	0.05	2521	0.02	1.1e-03	-7.48	7.22e-14	0.64	FALSE
Adipose	Ctsc	intron excision ratio	chr1_142031177_142045569	0.04	2521	0.03	4.0e-04	7.29	3.05e-13	0.61	FALSE
BLA	Ctsc	gene expression	Ctsc	0.1	1	0.08	7.2e-05	8.39	4.67e-17	0.8	TRUE
BLA	Tyr	gene expression	Tyr	0.11	1	0.05	1.4e-03	-5.94	2.93e-09	0.04	FALSE
BLA	Ctsc	isoform ratio	XM_008759637.3	0.05	1	0.03	1.2e-02	7.23	4.86e-13	0.04	FALSE
BLA	Grm5	isoform ratio	XM_017588778.2	0.12	1	0.06	3.4e-04	5.52	3.36e-08	0.04	TRUE
BLA	Grm5	isoform ratio	XM_017588780.2	0.06	2702	0.01	6.6e-02	7.42	1.15e-13	0.56	TRUE
Brain	Ctsc	alternative polyA	NM_017097.2	0.06	1	0.07	5.1e-07	-7.23	4.86e-13	0.01	FALSE
Brain	Ctsc	alternative polyA	XM_008759637.3	0.06	1	0.07	2.3e-07	7.74	9.58e-15	0.19	FALSE
Brain	Ctsc	gene expression	Ctsc	0.3	143	0.38	2.8e-37	6.26	3.82e-10	0	FALSE
Brain	Grm5	gene expression	Grm5	0.55	26	0.32	1.9e-30	-7.06	1.69e-12	0.53	FALSE
Brain	Ctsc	isoform ratio	NM_017097.2	0.06	1	0.06	4.1e-06	-7.76	8.25e-15	0.19	FALSE
Brain	Ctsc	isoform ratio	XM_008759637.3	0.06	1	0.06	1.2e-06	7.76	8.25e-15	0.2	FALSE
Brain	Grm5	isoform ratio	XM_017588780.2	0.05	93	0.04	2.2e-04	-7.78	7.30e-15	0.52	FALSE
Brain	Grm5	mRNA stability	Grm5	0.11	1	0.09	4.7e-09	-7.68	1.56e-14	0.02	FALSE
Eye	Ctsc	gene expression	Ctsc	0.37	2521	0.14	3.3e-03	-7.72	1.21e-14	0.17	FALSE
IL	Ctsc	gene expression	Ctsc	0.48	10	0.14	2.9e-04	-8	1.30e-15	0.64	FALSE
LHb	Ctsc	gene expression	Ctsc	0.19	168	0.12	9.8e-04	5.91	3.41e-09	0.17	FALSE
Liver	Ctsc	alternative TSS	NM_017097.2	0.06	1	0.05	3.3e-06	5.48	4.37e-08	0.01	FALSE
Liver	Ctsc	alternative TSS	XM_008759637.3	0.06	1	0.06	6.6e-07	-5.48	4.37e-08	0.01	FALSE
Liver	LOC102554680	gene expression	LOC102554680	0.04	2516	0.03	5.3e-04	-7.81	5.68e-15	0.64	FALSE
NAcc	Ctsc	gene expression	Ctsc	0.14	2521	0.16	1.5e-18	-7.38	1.57e-13	0.5	FALSE
NAcc	Grm5	gene expression	Grm5	0.05	1	0.05	1.4e-06	-7.92	2.39e-15	0.09	FALSE
NAcc	Ctsc	isoform ratio	NM_017097.2	0.03	1	0.04	2.3e-05	-7.35	2.04e-13	0.03	FALSE
NAcc	Ctsc	isoform ratio	XM_008759637.3	0.03	1	0.04	5.3e-05	7.35	2.04e-13	0.03	FALSE
NAcc	Grm5	isoform ratio	XM_017588779.2	0.05	2702	0.05	4.8e-06	-6.72	1.83e-11	0.58	FALSE
NAcc	Grm5	isoform ratio	XM_017588780.2	0.04	2702	0.03	1.1e-04	7.4	1.34e-13	0.71	TRUE
OFC	Grm5	gene expression	Grm5	0.29	2702	0.25	1.4e-06	5.66	1.49e-08	0.19	FALSE
PL	Ctsc	gene expression	Ctsc	0.2	2521	0.2	7.0e-22	-7	2.51e-12	0.09	FALSE
PL	Grm5	gene expression	Grm5	0.03	23	0.03	1.2e-04	7.76	8.71e-15	0.2	FALSE
PL	Ctsc	isoform ratio	NM_017097.2	0.02	1	0.01	4.8e-02	-5.88	4.20e-09	0.03	FALSE
PL	Ctsc	isoform ratio	XM_008759637.3	0.02	1	0.01	5.1e-02	5.88	4.20e-09	0.03	FALSE
PL	Grm5	isoform ratio	XM_006229659.4	0.02	2702	0.01	5.9e-02	-6.07	1.30e-09	0.22	FALSE
pVTA	Ctsc	gene expression	Ctsc	0.24	11	0.21	1.1e-09	6.57	4.94e-11	0.02	FALSE