Hub : Traits : Total locomotion distance, hab. session 1 : ← : →

chr1:140,614,300-142,727,457

Trait: Total locomotion distance, hab. session 1

Best TWAS P=2.88e-13 · Best GWAS P=2.81e-13 conditioned to 3.92e-215

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Ctsc	alternative polyA	ENSRNOT00000022342	0.16	2515	0.17	2.8e-18	5.46	4.80e-08	0	FALSE
Adipose	Ctsc	alternative polyA	ENSRNOT00000097085	0.17	2515	0.19	1.5e-20	-5.63	1.85e-08	0.03	FALSE
Adipose	Ctsc	isoform ratio	ENSRNOT00000022342	0.16	2515	0.16	4.3e-17	5.72	1.07e-08	0.19	FALSE
Adipose	Ctsc	isoform ratio	ENSRNOT00000097085	0.18	2515	0.18	1.3e-19	-5.85	4.94e-09	0.4	FALSE
Adipose	Ctsc	intron excision ratio	chr1:142031177:142036233	0.05	2515	0.04	6.5e-05	-6.02	1.73e-09	0.6	FALSE
Adipose	Ctsc	intron excision ratio	chr1:142031177:142045569	0.04	2515	0.02	4.7e-03	5.74	9.28e-09	0.49	FALSE
BLA	Ctsc	alternative polyA	ENSRNOT00000022342	0.07	2518	0.01	5.1e-02	5.51	3.54e-08	0.2	FALSE
BLA	Ctsc	alternative polyA	ENSRNOT00000097085	0.07	2518	0.02	3.2e-02	-5.3	1.16e-07	0.17	FALSE
BLA	Ctsc	gene expression	ENSRNOG00000016496	0.12	1	0.1	5.0e-06	-5.9	3.71e-09	0.03	FALSE
BLA	Ctsc	mRNA stability	ENSRNOG00000016496	0.05	1	0.03	1.5e-02	7.17	7.49e-13	0.1	FALSE
Brain	Grm5	gene expression	ENSRNOG00000016429	0.16	6	0.15	5.3e-14	6.24	4.50e-10	0.64	FALSE
Brain	Ctsc	gene expression	ENSRNOG00000016496	0.23	2518	0.31	4.5e-29	-5.32	1.06e-07	0	FALSE
Brain	Ctsc	isoform ratio	ENSRNOT00000022342	0.03	1	0.04	1.7e-04	7.3	2.88e-13	0.7	TRUE
Eye	Ctsc	gene expression	ENSRNOG00000016496	0.29	1	0.15	2.9e-03	-6.49	8.36e-11	0.06	FALSE
IL	Ctsc	gene expression	ENSRNOG00000016496	0.3	1	0.16	1.0e-04	-6.65	2.83e-11	0.06	FALSE
NAcc	Ctsc	gene expression	ENSRNOG00000016496	0.12	2516	0.12	3.3e-09	-6.16	7.41e-10	0.46	FALSE
PL	Ctsc	gene expression	ENSRNOG00000016496	0.14	87	0.13	8.2e-10	-5.62	1.94e-08	0.66	FALSE
PL	Grm5	mRNA stability	ENSRNOG00000016429	0.04	1	0.03	1.3e-03	-7.19	6.68e-13	0.06	FALSE