Hub : Traits : Total locomotion distance, hab. session 1 : →

chr1:140,610,199-142,727,457

Trait: Total locomotion distance, hab. session 1

Best TWAS P=2.88e-13 · Best GWAS P=2.81e-13 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Ctsc	isoform ratio	NM_017097.2	0.18	2521	0.16	5.6e-17	5.36	8.42e-08	0	FALSE
Adipose	Ctsc	isoform ratio	XM_008759637.3	0.19	2521	0.16	1.2e-17	-5.3	1.19e-07	0	FALSE
Adipose	Ctsc	intron excision ratio	chr1_142031177_142036233	0.05	2521	0.02	1.1e-03	-6.13	8.67e-10	0.63	FALSE
Adipose	Ctsc	intron excision ratio	chr1_142031177_142045569	0.04	2521	0.03	4.0e-04	5.94	2.90e-09	0.6	FALSE
BLA	Ctsc	gene expression	Ctsc	0.1	1	0.08	7.2e-05	7.3	2.88e-13	0.81	TRUE
BLA	Ctsc	isoform ratio	XM_008759637.3	0.05	1	0.03	1.2e-02	6.14	8.35e-10	0.04	FALSE
BLA	Grm5	isoform ratio	XM_017588780.2	0.06	2702	0.01	6.6e-02	6.76	1.37e-11	0.56	FALSE
Brain	Ctsc	alternative polyA	NM_017097.2	0.06	1	0.07	5.1e-07	-6.14	8.35e-10	0.02	FALSE
Brain	Ctsc	alternative polyA	XM_008759637.3	0.06	1	0.07	2.3e-07	6.59	4.50e-11	0.25	FALSE
Brain	Grm5	gene expression	Grm5	0.55	26	0.32	1.9e-30	-6.49	8.77e-11	0.57	FALSE
Brain	Ctsc	isoform ratio	NM_017097.2	0.06	1	0.06	4.1e-06	-6.65	3.01e-11	0.29	FALSE
Brain	Ctsc	isoform ratio	XM_008759637.3	0.06	1	0.06	1.2e-06	6.65	3.01e-11	0.32	FALSE
Brain	Grm5	isoform ratio	XM_017588780.2	0.05	93	0.04	2.2e-04	-6.49	8.44e-11	0.54	FALSE
Brain	Grm5	mRNA stability	Grm5	0.11	1	0.09	4.7e-09	-6.52	7.24e-11	0.04	TRUE
Eye	Ctsc	gene expression	Ctsc	0.37	2521	0.14	3.3e-03	-6.58	4.58e-11	0.2	FALSE
IL	Ctsc	gene expression	Ctsc	0.48	10	0.14	2.9e-04	-6.71	1.95e-11	0.63	FALSE
Liver	LOC102554680	gene expression	LOC102554680	0.04	2516	0.03	5.3e-04	-6.64	3.23e-11	0.64	FALSE
NAcc	Ctsc	gene expression	Ctsc	0.14	2521	0.16	1.5e-18	-6.07	1.29e-09	0.52	FALSE
NAcc	Grm5	gene expression	Grm5	0.05	1	0.05	1.4e-06	-6.8	1.04e-11	0.17	FALSE
NAcc	Ctsc	isoform ratio	NM_017097.2	0.03	1	0.04	2.3e-05	-6.2	5.83e-10	0.03	FALSE
NAcc	Ctsc	isoform ratio	XM_008759637.3	0.03	1	0.04	5.3e-05	6.2	5.83e-10	0.03	FALSE
NAcc	Grm5	isoform ratio	XM_017588779.2	0.05	2702	0.05	4.8e-06	-6.27	3.71e-10	0.58	FALSE
NAcc	Grm5	isoform ratio	XM_017588780.2	0.04	2702	0.03	1.1e-04	6.49	8.76e-11	0.69	FALSE
OFC	Grm5	gene expression	Grm5	0.29	2702	0.25	1.4e-06	5.66	1.55e-08	0.19	FALSE
PL	Ctsc	gene expression	Ctsc	0.2	2521	0.2	7.0e-22	-5.6	2.12e-08	0.17	FALSE
PL	Grm5	gene expression	Grm5	0.03	23	0.03	1.2e-04	6.84	7.69e-12	0.2	TRUE
PL	Grm5	isoform ratio	XM_006229659.4	0.02	2702	0.01	5.9e-02	-5.95	2.76e-09	0.21	FALSE
pVTA	Ctsc	gene expression	Ctsc	0.24	11	0.21	1.1e-09	5.42	5.82e-08	0.02	FALSE