chr19:39,128,051-41,694,539

Trait: Light reinforcement 1

Best TWAS P = 2.39e-08 · Best GWAS P= 5.48e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h²	# weights	Model R²	Model R² P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Gcdh	isoform ratio	XM_063278172.1	0.08	1060	0.07	3.6e-08	-5.22	1.75e-07	0.88	FALSE
Adipose	Gadd45gip1	mRNA stability	Gadd45gip1	0.34	1	0.25	1.3e-27	5.25	1.55e-07	0.86	FALSE
BLA	Cacna1a	isoform ratio	XM_063277795.1	0.07	1	0.03	1.0e-02	-5.3	1.13e-07	0.08	FALSE
BLA	Brme1	mRNA stability	Brme1	0.09	1639	0.02	1.8e-02	-5.29	1.23e-07	0.7	FALSE
Brain	Gcdh	gene expression	Gcdh	0.57	61	0.53	1.1e-57	5.31	1.08e-07	0.88	FALSE
Brain	LOC102555451	gene expression	LOC102555451	0.26	1772	0.24	7.8e-22	5.31	1.12e-07	0.84	FALSE
Brain	Gcdh	intron excision ratio	chr19_40168905_40169025	0.1	1	0.07	2.5e-07	-5.25	1.55e-07	0.87	FALSE
IC	Cacna1a	alternative polyA	NM_012918.5	0.13	1	0.08	2.3e-04	5.27	1.37e-07	0.2	FALSE
IC	C19h19orf53	gene expression	C19h19orf53	0.1	1400	0.02	5.6e-02	5.28	1.29e-07	0.45	FALSE
IC	Cacna1a	gene expression	Cacna1a	0.12	1	0.09	1.7e-04	5.23	1.70e-07	0.12	FALSE
IC	Ervk-21l3	gene expression	Ervk-21l3	0.56	10	0.36	7.3e-16	5.28	1.30e-07	0.01	FALSE
IC	Gcdh	gene expression	Gcdh	0.3	1	0.17	1.3e-07	5.28	1.30e-07	0.86	FALSE
IC	LOC102555451	gene expression	LOC102555451	0.38	1	0.21	2.6e-09	-5.23	1.70e-07	0.88	FALSE
IC	Cacna1a	isoform ratio	NM_012918.5	0.09	1	0.06	1.1e-03	5.27	1.37e-07	0.07	FALSE
IC	Gcdh	intron excision ratio	chr19_40168905_40169025	0.18	18	0.1	5.3e-05	5.32	1.05e-07	0.86	FALSE
IC	Gadd45gip1	mRNA stability	Gadd45gip1	0.18	1108	0.06	2.2e-03	-5.45	4.91e-08	0.72	FALSE
IC	LOC102555451	mRNA stability	LOC102555451	0.21	1625	0.1	8.3e-05	5.27	1.39e-07	0.79	FALSE
Liver	Gcdh	gene expression	Gcdh	0.39	41	0.31	1.1e-34	-5.23	1.66e-07	0.89	FALSE
Liver	Klf1	gene expression	Klf1	0.04	1	0.03	1.6e-04	5.36	8.46e-08	0.2	FALSE
Liver	Gadd45gip1	mRNA stability	Gadd45gip1	0.12	1	0.09	1.8e-10	5.25	1.55e-07	0.86	FALSE
NAcc	Cacna1a	alternative TSS	XM_063277790.1	0.02	1535	0.01	1.1e-02	-5.42	5.85e-08	0.66	FALSE
NAcc	Cacna1a	alternative TSS	XM_063277790.1	0.02	1535	0.01	6.8e-03	-5.38	7.32e-08	0.61	FALSE
NAcc	MAST1	gene expression	MAST1	0.12	1	0.08	2.5e-12	-5.28	1.30e-07	0.9	FALSE
NAcc	Mri1	gene expression	Mri1	0.19	21	0.18	4.3e-27	5.23	1.74e-07	0.84	FALSE
NAcc	Gcdh	isoform ratio	NM_001108896.1	0.44	27	0.32	5.6e-49	5.45	5.13e-08	0.85	FALSE
NAcc	Gcdh	isoform ratio	XM_063278172.1	0.52	24	0.37	2.1e-59	-5.35	8.84e-08	0.88	FALSE
NAcc	Gcdh	intron excision ratio	chr19_40169087_40169428	0.03	1	0.01	2.4e-02	-5.28	1.30e-07	0.1	FALSE
NAcc	Rad23a	mRNA stability	Rad23a	0.04	7	0.02	1.8e-04	5.45	4.91e-08	0.81	FALSE
PL	C19h19orf53	gene expression	C19h19orf53	0.07	1568	0.06	4.9e-07	5.3	1.17e-07	0.82	FALSE
PL	Nfix	gene expression	Nfix	0.03	1	0.01	1.5e-02	-5.25	1.55e-07	0.05	FALSE
PL	Gadd45gip1	mRNA stability	Gadd45gip1	0.14	101	0.09	6.5e-10	5.34	9.50e-08	0.85	FALSE
pVTA	Nfix	gene expression	Nfix	0.1	20	0.04	2.2e-04	-5.58	2.39e-08	0.83	TRUE
RMTg	Gcdh	isoform ratio	XM_063278172.1	0.35	939	0.18	1.6e-05	-5.5	3.79e-08	0.85	FALSE