Best TWAS P=2.59e-09 · Best GWAS P=3.37e-07 conditioned to 5.21e-01
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Pecam1 | gene expression | Pecam1 | 0.08 | 2205 | 0.04 | 1.4e-05 | 5.23 | 1.74e-07 | 0.5 | FALSE |
| Liver | Map3k3 | gene expression | Map3k3 | 0.03 | 1898 | 0.01 | 4.9e-02 | 5.58 | 2.34e-08 | 0.47 | FALSE |
| Liver | Psmc5 | gene expression | Psmc5 | 0.04 | 2096 | 0.02 | 4.9e-03 | 5.96 | 2.59e-09 | 0.49 | TRUE |
| Liver | Ccdc47 | mRNA stability | Ccdc47 | 0.05 | 2063 | 0.01 | 7.8e-03 | -5.71 | 1.12e-08 | 0.78 | FALSE |