Hub : Traits : Extensor digitorum longus weight : ← : →

chr10:87,653,044-92,850,954

Trait: Extensor digitorum longus weight

Best TWAS P = 6.00e-09 · Best GWAS P= 6.29e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Acbd4	alternative polyA	XM_063269169.1	0.55	177	0.56	1.6e-74	5.57	2.51e-08	0.79	FALSE
Adipose	Acbd4	alternative polyA	XM_063269169.1	0.54	170	0.56	7.2e-75	5.36	8.10e-08	0.79	TRUE
Adipose	Nmt1	alternative polyA	XM_039085301.2	0.06	1	0.05	2.9e-06	-5.34	9.49e-08	0.75	FALSE
Adipose	Nmt1	alternative polyA	XM_039085301.2	0.06	1	0.05	3.6e-06	-5.34	9.49e-08	0.75	FALSE
Adipose	Fmnl1	gene expression	Fmnl1	0.25	1	0.2	1.2e-21	5.36	8.34e-08	0.78	FALSE
Adipose	Pecam1	gene expression	Pecam1	0.08	2283	0.04	1.1e-05	5.33	9.62e-08	0.57	FALSE
Adipose	Acbd4	isoform ratio	XM_063269164.1	0.02	1	0	9.7e-02	-5.41	6.42e-08	0.06	FALSE
Adipose	Acbd4	isoform ratio	XM_063269167.1	0.04	1	0.04	2.4e-05	-5.35	8.59e-08	0.31	FALSE
Adipose	Eftud2	mRNA stability	Eftud2	0.07	1	0.06	2.9e-07	-5.34	9.38e-08	0.74	FALSE
Adipose	Fmnl1	mRNA stability	Fmnl1	0.09	2276	0.07	2.1e-08	-5.49	3.91e-08	0.74	FALSE
BLA	Nmt1	alternative polyA	NM_148891.2	0.08	134	0.03	1.5e-02	5.27	1.38e-07	0.57	TRUE
BLA	Acbd4	gene expression	Acbd4	0.49	2284	0.27	7.3e-15	-5.21	1.90e-07	0.76	FALSE
BLA	Crhr1	gene expression	Crhr1	0.31	2651	0.14	5.1e-08	5.34	9.26e-08	0.65	FALSE
BLA	Mapt	isoform ratio	NM_017212.3	0.28	1	0.15	4.0e-08	-5.22	1.76e-07	0.92	FALSE
Brain	Acbd4	alternative polyA	XM_063269169.1	0.16	1	0.16	3.4e-15	5.36	8.34e-08	0.78	FALSE
Brain	Acbd4	alternative polyA	XM_063269169.1	0.16	1	0.17	3.4e-15	5.36	8.34e-08	0.78	FALSE
Brain	Acbd4	isoform ratio	XM_063269171.1	0.13	1	0.13	6.5e-12	5.26	1.42e-07	0.68	FALSE
Brain	Acbd4	intron excision ratio	chr10_88550129_88550557	0.2	1	0.12	5.1e-11	5.21	1.85e-07	0.62	FALSE
IC	Acbd4	intron excision ratio	chr10_88550129_88550557	0.24	1	0.24	1.8e-10	5.33	9.59e-08	0.75	FALSE
IC	Gosr2	intron excision ratio	chr10_89087914_89095036	0.15	2721	0.14	1.5e-06	-5.29	1.21e-07	0.77	TRUE
IL	Eftud2	gene expression	Eftud2	0.36	1	0.23	2.5e-06	-5.35	9.01e-08	0.2	FALSE
LHb	Eftud2	mRNA stability	Eftud2	0.24	1	0.11	1.7e-03	-5.24	1.56e-07	0.07	FALSE
Liver	Dcakd	mRNA stability	Dcakd	0.07	38	0.05	7.5e-06	-5.27	1.34e-07	0.76	TRUE
NAcc	Gfap	gene expression	Gfap	0.07	1	0.07	2.4e-11	5.26	1.42e-07	0.69	FALSE
NAcc	Hexim2	gene expression	Hexim2	0.03	2335	0.03	5.2e-05	-5.39	7.11e-08	0.73	TRUE
NAcc	LOC108352144	gene expression	LOC108352144	0.05	1	0.05	3.8e-08	-5.26	1.40e-07	0.98	TRUE
NAcc	Acbd4	isoform ratio	XM_063269171.1	0.05	1	0.07	2.1e-10	5.32	1.02e-07	0.74	FALSE
NAcc	Acbd4	intron excision ratio	chr10_88550129_88550557	0.15	26	0.22	2.7e-32	-5.34	9.14e-08	0.77	FALSE
NAcc	Dcakd	mRNA stability	Dcakd	0.03	1	0.03	7.5e-05	-5.33	9.68e-08	0.46	FALSE
OFC	Tlk2	isoform ratio	XM_039086138.2	0.36	3342	0.2	1.4e-05	-5.49	4.02e-08	0.57	TRUE
PL	Icam2	alternative TSS	XM_063269469.1	0.06	13	0.05	3.2e-06	5.25	1.50e-07	0.34	FALSE
PL	Wnt3	alternative TSS	XM_017597028.3	0.02	2724	0.01	6.3e-02	-5.22	1.80e-07	0.52	FALSE
PL	Crhr1	gene expression	Crhr1	0.19	1	0.19	3.5e-20	-5.22	1.76e-07	0.91	FALSE
PL	Acbd4	intron excision ratio	chr10_88550129_88550557	0.15	19	0.15	2.5e-16	-5.25	1.51e-07	0.72	FALSE
pVTA	Cyb561	alternative TSS	NM_001107056.3	0.08	84	0.02	4.5e-03	-5.79	7.17e-09	0.16	FALSE
pVTA	Cyb561	alternative TSS	XM_008768357.4	0.09	103	0.02	5.3e-03	5.82	6.00e-09	0.16	TRUE
pVTA	Wnt3	alternative TSS	NM_001105715.2	0.08	2724	0.04	5.5e-04	5.44	5.45e-08	0.58	FALSE
pVTA	Wnt3	alternative TSS	XM_017597028.3	0.09	2724	0.04	2.3e-04	-5.37	7.93e-08	0.6	TRUE
pVTA	Wnt3	isoform ratio	NM_001105715.2	0.08	2724	0.03	1.4e-03	5.43	5.60e-08	0.49	FALSE
pVTA	Wnt3	isoform ratio	XM_017597028.3	0.08	2724	0.03	1.1e-03	-5.4	6.64e-08	0.5	FALSE
pVTA	Gosr2	intron excision ratio	chr10_89087914_89095036	0.05	2721	0.02	8.6e-03	-5.41	6.14e-08	0.75	FALSE
pVTA	Dcakd	mRNA stability	Dcakd	0.09	1	0.09	2.4e-07	-5.34	9.49e-08	0.75	FALSE
pVTA	Mapt	mRNA stability	Mapt	0.07	72	0.01	4.1e-02	5.38	7.38e-08	0.03	FALSE
RMTg	Acbd4	alternative polyA	XM_008768287.4	0.14	2284	0.09	2.8e-03	5.35	8.62e-08	0.41	FALSE
RMTg	Acbd4	alternative polyA	XM_063269169.1	0.17	2284	0.06	1.1e-02	-5.37	7.88e-08	0.57	FALSE
RMTg	Gfap	mRNA stability	Gfap	0.21	1	0.14	1.2e-04	-5.26	1.42e-07	0.11	TRUE