Hub : Traits : Extensor digitorum longus weight : ← : →

chr12:4,393,425-10,174,895

Trait: Extensor digitorum longus weight

Best TWAS P = 1.13e-09 · Best GWAS P= 5.41e-08 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Pet100	alternative polyA	NM_001195245.1	0.13	18	0.05	1.6e-06	-5.43	5.56e-08	0.66	FALSE
Adipose	Pet100	alternative polyA	XM_039089765.2	0.13	12	0.05	1.1e-06	5.45	5.06e-08	0.68	FALSE
Adipose	Snapc2	alternative TSS	NM_001415804.1	0.05	2607	0.02	8.9e-04	-6.02	1.73e-09	0.51	FALSE
Adipose	LOC102552452	gene expression	LOC102552452	0.39	113	0.2	5.2e-22	5.6	2.11e-08	0.19	FALSE
Adipose	LOC134481141	gene expression	LOC134481141	0.08	1442	0.06	1.4e-07	5.27	1.33e-07	0.69	FALSE
Adipose	Map2k7	gene expression	Map2k7	0.06	2566	0.04	4.6e-05	-5.76	8.66e-09	0.4	FALSE
Adipose	Stard13	gene expression	Stard13	0.3	36	0.23	2.4e-25	5.24	1.59e-07	0.1	TRUE
Adipose	LOC102552452	isoform ratio	XM_063271839.1	0.03	1	0.01	3.1e-02	-5.31	1.09e-07	0.04	FALSE
Adipose	LOC102552452	isoform ratio	XM_063271845.1	0.19	2711	0.13	4.3e-14	-5.83	5.46e-09	0.34	FALSE
Adipose	Elavl1	mRNA stability	Elavl1	0.29	2736	0.15	3.0e-16	5.7	1.22e-08	0.18	FALSE
BLA	Snapc2	alternative TSS	NM_001415804.1	0.09	2607	0.04	4.7e-03	-5.97	2.41e-09	0.46	FALSE
BLA	Snapc2	alternative TSS	NM_001415804.1	0.09	3	0.04	5.0e-03	-5.93	3.09e-09	0.42	FALSE
BLA	Zfp958	gene expression	Zfp958	0.05	992	0.03	7.9e-03	-5.58	2.38e-08	0.31	FALSE
BLA	Cers4	mRNA stability	Cers4	0.15	2436	0.06	4.9e-04	5.21	1.84e-07	0.17	FALSE
Brain	Arhgef18	gene expression	Arhgef18	0.11	6	0.06	1.0e-06	-5.3	1.16e-07	0.74	FALSE
Brain	LOC102552452	isoform ratio	XM_063271838.1	0.04	67	0.03	3.6e-04	5.27	1.38e-07	0.6	FALSE
Brain	LOC102552452	isoform ratio	XM_063271841.1	0.15	338	0.15	1.3e-13	5.7	1.19e-08	0.64	TRUE
Brain	LOC120095871	isoform ratio	XM_039089913.2	0.1	19	0.08	3.5e-08	-5.36	8.47e-08	0.8	FALSE
Brain	Pet100	intron excision ratio	chr12_6478691_6478860	0.07	11	0.04	7.1e-05	-5.25	1.51e-07	0.48	FALSE
Brain	Pet100	intron excision ratio	chr12_6478892_6479405	0.05	7	0.04	2.6e-04	5.26	1.43e-07	0.45	TRUE
Brain	Elavl1	mRNA stability	Elavl1	0.18	2736	0.11	2.8e-10	5.72	1.06e-08	0.25	FALSE
Eye	Elavl1	intron excision ratio	chr12_7465304_7482490	0.66	12	0.37	9.1e-07	5.64	1.66e-08	0.2	FALSE
IC	Snapc2	alternative TSS	NM_001415804.1	0.29	2607	0.11	3.2e-05	-6.02	1.72e-09	0.66	FALSE
IC	Snapc2	alternative TSS	XM_039089313.2	0.1	1	0.09	1.8e-04	-5.26	1.44e-07	0.11	FALSE
IC	Snapc2	alternative TSS	NM_001415804.1	0.3	1	0.13	4.2e-06	5.26	1.46e-07	0.58	FALSE
IC	Zfp958	alternative TSS	NM_001419319.1	0.17	15	0.13	3.4e-06	-5.27	1.35e-07	0.44	FALSE
IC	Zfp958	alternative TSS	XM_063270976.1	0.18	16	0.14	2.2e-06	5.28	1.28e-07	0.42	TRUE
IC	Snapc2	gene expression	Snapc2	0.64	34	0.37	2.3e-16	-5.74	9.29e-09	0.64	FALSE
IC	Snapc2	isoform ratio	NM_001415804.1	0.23	2607	0.08	3.9e-04	-6.09	1.13e-09	0.63	TRUE
IC	Arhgef18	intron excision ratio	chr12_6233723_6272690	0.11	1616	0.04	6.6e-03	-5.23	1.66e-07	0.57	FALSE
IC	Snapc2	intron excision ratio	chr12_7404178_7404805	0.2	2607	0.08	3.3e-04	-6.02	1.73e-09	0.6	FALSE
IL	Pet100	alternative TSS	NM_001195245.1	0.65	47	0.24	2.3e-06	5.35	8.97e-08	0.62	FALSE
IL	Pet100	alternative TSS	XM_039089765.2	0.67	33	0.24	1.7e-06	-5.35	8.66e-08	0.66	FALSE
IL	Cers4	gene expression	Cers4	0.36	1	0.26	6.6e-07	-5.35	8.79e-08	0.28	FALSE
IL	Snapc2	gene expression	Snapc2	0.37	11	0.04	4.3e-02	-5.72	1.07e-08	0.29	FALSE
LHb	Pet100	alternative TSS	NM_001195245.1	0.66	23	0.35	2.7e-09	5.4	6.85e-08	0.62	FALSE
LHb	Pet100	alternative TSS	XM_039089765.2	0.6	24	0.31	3.5e-08	-5.39	6.95e-08	0.58	FALSE
LHb	Arhgef18	gene expression	Arhgef18	0.34	81	0.18	5.1e-05	5.23	1.70e-07	0.52	FALSE
LHb	Cers4	gene expression	Cers4	0.3	117	0.14	3.5e-04	-5.6	2.14e-08	0.2	FALSE
Liver	N4bp2l1	gene expression	N4bp2l1	0.21	185	0.16	8.6e-18	5.3	1.14e-07	0.87	FALSE
Liver	LOC102552452	isoform ratio	XM_063271841.1	0.37	84	0.24	2.6e-26	5.59	2.33e-08	0.52	FALSE
Liver	Pet100	intron excision ratio	chr12_6478691_6478860	0.21	1869	0.09	2.7e-10	-5.52	3.42e-08	0.75	FALSE
Liver	Pet100	intron excision ratio	chr12_6478892_6479405	0.18	1869	0.07	4.8e-08	5.61	2.07e-08	0.79	FALSE
Liver	Elavl1	mRNA stability	Elavl1	0.09	50	0.05	6.6e-06	-5.59	2.31e-08	0.22	FALSE
Liver	Pet100	mRNA stability	Pet100	0.89	11	0.26	6.4e-29	5.28	1.29e-07	0.73	FALSE
NAcc	Pet100	alternative polyA	NM_001195245.1	0.12	1869	0.06	4.7e-10	5.29	1.20e-07	0.7	FALSE
NAcc	Snapc2	alternative TSS	NM_001013121.1	0.03	2602	0.01	2.0e-02	-5.48	4.19e-08	0.2	TRUE
NAcc	Snapc2	alternative TSS	NM_001415804.1	0.13	2607	0.08	1.8e-12	-5.33	1.01e-07	0.54	FALSE
NAcc	Snapc2	alternative TSS	XM_039089313.2	0.12	66	0.08	4.5e-12	-5.79	7.23e-09	0.63	FALSE
NAcc	Snapc2	alternative TSS	NM_001415804.1	0.12	2607	0.08	2.9e-12	-5.43	5.60e-08	0.56	FALSE
NAcc	Snapc2	alternative TSS	XM_039089313.2	0.11	2607	0.07	6.7e-11	5.86	4.76e-09	0.65	FALSE
NAcc	Cers4	gene expression	Cers4	0.39	181	0.43	7.9e-71	-5.89	3.76e-09	0.61	FALSE
NAcc	Snapc2	gene expression	Snapc2	0.2	2607	0.11	5.9e-17	-5.59	2.22e-08	0.24	FALSE
NAcc	Zfp958	gene expression	Zfp958	0.11	44	0.1	1.0e-14	5.7	1.20e-08	0.38	FALSE
NAcc	Zfp958l1	gene expression	Zfp958l1	0.16	5	0.14	4.8e-20	-5.24	1.56e-07	0.58	FALSE
NAcc	Pet100	isoform ratio	NM_001195245.1	0.1	3	0.06	1.9e-09	-5.24	1.64e-07	0.78	FALSE
NAcc	Pet100	isoform ratio	XM_039089765.2	0.11	3	0.06	6.0e-10	5.26	1.47e-07	0.8	FALSE
NAcc	Snapc2	isoform ratio	NM_001415804.1	0.15	2607	0.08	9.2e-13	-5.71	1.10e-08	0.58	FALSE
NAcc	Snapc2	isoform ratio	XM_039089313.2	0.1	2607	0.06	2.7e-09	5.97	2.43e-09	0.43	FALSE
NAcc	N4bp2l2	mRNA stability	N4bp2l2	0.05	726	0.05	1.5e-07	-5.25	1.55e-07	0.81	FALSE
NAcc	Zfp958	mRNA stability	Zfp958	0.05	996	0.03	1.6e-05	-5.27	1.39e-07	0.26	FALSE
OFC	Pet100	alternative TSS	NM_001195245.1	0.57	1869	0.27	3.5e-07	5.43	5.76e-08	0.64	FALSE
OFC	Pet100	alternative TSS	XM_039089765.2	0.59	1869	0.3	6.6e-08	-5.4	6.67e-08	0.63	FALSE
OFC	Cers4	gene expression	Cers4	0.57	1	0.36	1.5e-09	-5.31	1.09e-07	0.69	FALSE
OFC	Snapc2	gene expression	Snapc2	0.5	2607	0.06	1.5e-02	-5.97	2.32e-09	0.4	FALSE
PL	Pet100	alternative polyA	NM_001195245.1	0.36	104	0.2	6.4e-22	-5.69	1.27e-08	0.77	FALSE
PL	Pet100	alternative polyA	XM_039089765.2	0.34	114	0.18	1.2e-19	5.72	1.07e-08	0.78	FALSE
PL	Snapc2	alternative TSS	XM_039089313.2	0.12	1	0.1	2.0e-11	-5.35	8.79e-08	0.81	FALSE
PL	Snapc2	alternative TSS	XM_039089313.2	0.1	1	0.08	2.3e-09	-5.35	8.79e-08	0.81	FALSE
PL	LOC120095871	gene expression	LOC120095871	0.06	1121	0.04	4.2e-05	5.77	8.08e-09	0.72	FALSE
PL	Snapc2	gene expression	Snapc2	0.36	2607	0.2	9.1e-22	-5.97	2.33e-09	0.61	FALSE
PL	Pet100	isoform ratio	NM_001195245.1	0.11	6	0.06	5.3e-07	-5.32	1.04e-07	0.65	FALSE
PL	Pet100	isoform ratio	XM_039089765.2	0.1	15	0.05	2.2e-06	-5.28	1.31e-07	0.66	FALSE
PL	Snapc2	isoform ratio	NM_001415804.1	0.19	2607	0.19	1.1e-20	-5.21	1.87e-07	0.58	FALSE
PL	Pet100	intron excision ratio	chr12_6478691_6478860	0.24	14	0.12	2.6e-13	5.26	1.44e-07	0.8	FALSE
PL	Pet100	intron excision ratio	chr12_6478892_6479405	0.19	10	0.09	1.9e-10	5.23	1.69e-07	0.79	FALSE
PL	Zfp958	mRNA stability	Zfp958	0.04	996	0.02	5.8e-03	-5.6	2.16e-08	0.46	FALSE
pVTA	Arhgef18	gene expression	Arhgef18	0.29	58	0.25	4.0e-20	-5.27	1.37e-07	0.68	FALSE
pVTA	Cers4	gene expression	Cers4	0.39	27	0.44	3.6e-38	5.99	2.08e-09	0.19	FALSE
pVTA	Retn	gene expression	Retn	0.18	1863	0.1	4.3e-08	-5.3	1.16e-07	0.51	FALSE
pVTA	Pet100	intron excision ratio	chr12_6478691_6478860	0.1	4	0.06	6.6e-06	-5.42	6.01e-08	0.73	FALSE
pVTA	Pet100	intron excision ratio	chr12_6478892_6479405	0.08	3	0.06	2.1e-05	5.41	6.19e-08	0.77	FALSE
pVTA	Cers4	mRNA stability	Cers4	0.04	2436	0	2.6e-01	5.8	6.75e-09	0.19	FALSE
RMTg	Pet100	alternative polyA	NM_001195245.1	0.53	2	0.21	2.3e-06	5.29	1.25e-07	0.75	FALSE
RMTg	LOC120095871	intron excision ratio	chr12_8668790_8671501	0.18	1121	0.07	5.5e-03	-5.28	1.28e-07	0.22	FALSE