Best TWAS P=4.167565e-08 · Best GWAS P=7.721958e-10 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Has2 | gene expression | ENSRNOG00000004854 | 0.08 | 0.02 | top1 | 1 | 0.02 | 0.0023 | -5.5 | -5.5 | 4.2e-08 | 0.97 | 0.07 | 0.03 | TRUE |
| 2 | Adipose | NA | gene expression | ENSRNOG00000069488 | 0.03 | 0.01 | top1 | 1 | 0.01 | 0.0099 | -5.4 | -5.4 | 7.0e-08 | 0.96 | 0.06 | 0.03 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.