Best TWAS P=6.815433e-08 · Best GWAS P=5.884691e-08 conditioned to 0
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Med30 | intron excision ratio | chr7:84012067:84015230 | 0.06 | 0.02 | enet | 68 | 0.02 | 1.1e-03 | -5.0 | -5.2 | 2.4e-07 | 0.66 | 0.43 | 0.44 | TRUE |
| 2 | OFC | NA | intron excision ratio | chr7:84967032:85057234 | 0.30 | 0.12 | top1 | 1 | 0.12 | 9.2e-04 | -5.4 | 5.4 | 6.8e-08 | -0.71 | 0.12 | 0.06 | TRUE |
| 3 | OFC | Ext1 | mRNA stability | ENSRNOG00000024886 | 0.44 | 0.10 | blup | 1838 | 0.17 | 8.7e-05 | -5.3 | 5.4 | 7.3e-08 | -0.92 | 0.36 | 0.57 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.