Best TWAS P=1.294534e-07 · Best GWAS P=2.756758e-07 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Egln3 | gene expression | ENSRNOG00000005053 | 0.07 | 0.02 | lasso | 4 | 0.03 | 0.00046 | -4.9 | 5.3 | 1.3e-07 | -0.92 | 0.05 | 0.94 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.