Hub : Traits : BMI with tail : ← →

chr10:92,588,108-95,279,450

Trait: BMI with tail

Best TWAS P=1.784212e-08 · Best GWAS P=4.963239e-09 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Cep112	intron excision ratio	chr10:93731914:93738578	0.06	0.04	top1	1	0.04	4.2e-05	-5.6	5.6	2.8e-08	-0.94	0.18	0.25	FALSE
2	BLA	Axin2	gene expression	ENSRNOG00000055010	0.07	0.08	top1	1	0.08	4.9e-05	-5.1	-5.1	3.0e-07	0.96	0.13	0.05	FALSE
3	Brain	Prkca	gene expression	ENSRNOG00000003491	0.12	0.08	top1	1	0.08	4.3e-08	-5.6	-5.6	1.8e-08	0.95	0.25	0.74	TRUE
4	Brain	AABR07030647.1	gene expression	ENSRNOG00000033613	0.07	0.09	top1	1	0.09	2.0e-08	-5.4	5.4	7.8e-08	-0.94	0.38	0.61	FALSE
5	IL	Amz2	gene expression	ENSRNOG00000000246	0.32	0.15	blup	2767	0.17	6.0e-05	4.8	5.1	2.9e-07	-0.91	0.33	0.65	FALSE
6	IL	Axin2	gene expression	ENSRNOG00000055010	0.32	0.17	blup	2027	0.23	3.1e-06	-5.6	-5.3	9.5e-08	0.89	0.46	0.51	FALSE
7	LHb	Cep112	gene expression	ENSRNOG00000024557	0.35	0.25	top1	1	0.25	1.5e-06	-5.6	-5.6	2.3e-08	0.96	0.14	0.13	FALSE
8	Liver	Cep112	isoform ratio	ENSRNOT00000037067	0.03	0.02	top1	1	0.02	2.3e-03	-5.6	5.6	2.5e-08	-0.99	0.07	0.05	FALSE
9	Liver	Apoh	mRNA stability	ENSRNOG00000003566	0.27	0.26	enet	72	0.27	2.3e-29	-5.8	5.6	2.0e-08	-0.99	0.30	0.70	FALSE
10	NAcc	Cep112	alternative TSS	ENSRNOT00000108519	0.13	0.11	top1	1	0.11	1.2e-08	-5.6	-5.6	2.6e-08	0.93	0.37	0.63	FALSE
11	NAcc	Cep112	gene expression	ENSRNOG00000024557	0.06	0.07	top1	1	0.07	1.1e-05	-5.5	-5.5	4.2e-08	0.91	0.22	0.20	FALSE
12	NAcc	Cep112	isoform ratio	ENSRNOT00000108519	0.14	0.11	blup	2251	0.12	2.5e-09	-5.6	-5.5	3.3e-08	0.91	0.34	0.66	FALSE
13	NAcc	Wipi1	mRNA stability	ENSRNOG00000003827	0.06	0.02	top1	1	0.02	6.2e-03	-5.5	5.5	4.1e-08	-0.83	0.09	0.12	FALSE
14	PL	Rgs9	alternative polyA	ENSRNOT00000096063	0.04	0.02	top1	1	0.02	9.1e-03	5.2	-5.2	2.6e-07	0.90	0.09	0.04	FALSE
15	PL	Cep112	gene expression	ENSRNOG00000024557	0.14	0.10	top1	1	0.10	2.4e-08	-5.5	-5.5	4.2e-08	0.99	0.48	0.52	FALSE
16	PL	Rgs9	isoform ratio	ENSRNOT00000005076	0.06	0.03	top1	1	0.03	1.4e-03	-5.1	5.1	2.8e-07	-0.90	0.13	0.08	FALSE
17	PL	Rgs9	isoform ratio	ENSRNOT00000096063	0.04	0.02	top1	1	0.02	6.4e-03	5.2	-5.2	2.6e-07	0.90	0.09	0.04	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.