Hub : Traits : dissection: UMAP 3 of all traits : ← →

chr2:34,186,973-36,646,696

Best TWAS P=1.501789e-07 · Best GWAS P=9.352767e-08 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Trim23	gene expression	ENSRNOG00000012354	0.09	0.03	blup	873	0.03	1.5e-04	-5.0	-5.1	3.3e-07	0.95	0.37	0.62	FALSE
2	Adipose	Trim23	isoform ratio	ENSRNOT00000106700	0.02	0.01	top1	1	0.01	8.3e-03	-5.2	5.2	2.2e-07	-0.96	0.03	0.03	FALSE
3	BLA	Trim23	alternative polyA	ENSRNOT00000016649	0.08	0.05	top1	1	0.04	1.9e-03	5.1	-5.1	2.7e-07	0.96	0.06	0.09	FALSE
4	BLA	Trim23	alternative polyA	ENSRNOT00000106700	0.08	0.05	top1	1	0.05	1.1e-03	5.1	5.1	2.7e-07	-0.96	0.06	0.11	FALSE
5	Brain	Srek1ip1	alternative TSS	ENSRNOT00000095129	0.03	0.03	top1	1	0.03	4.9e-04	-5.1	-5.1	2.8e-07	0.97	0.05	0.10	FALSE
6	Liver	Erbin	gene expression	ENSRNOG00000047137	0.09	0.06	blup	932	0.06	2.5e-07	-5.1	5.1	3.0e-07	-0.94	0.41	0.59	FALSE
7	Liver	Nln	isoform ratio	ENSRNOT00000066925	0.03	0.02	top1	1	0.02	1.9e-03	-5.2	5.2	2.2e-07	-0.96	0.04	0.05	FALSE
8	Liver	Nln	isoform ratio	ENSRNOT00000082755	0.03	0.02	top1	1	0.02	3.4e-03	-5.2	-5.2	2.2e-07	0.96	0.04	0.05	FALSE
9	NAcc	Erbin	gene expression	ENSRNOG00000047137	0.19	0.06	blup	932	0.06	1.7e-02	-5.1	-5.1	3.3e-07	0.95	0.24	0.29	FALSE
10	NAcc2	Trappc13	gene expression	ENSRNOG00000012124	0.05	0.02	top1	1	0.02	2.8e-02	-5.1	5.1	2.8e-07	-0.96	0.04	0.06	FALSE
11	NAcc2	Srek1	gene expression	ENSRNOG00000032735	0.07	0.06	top1	1	0.06	2.4e-04	-5.3	-5.3	1.5e-07	0.94	0.06	0.08	TRUE
12	NAcc2	Cenpk	isoform ratio	ENSRNOT00000103473	0.09	0.06	enet	34	0.06	3.0e-04	-5.2	-5.2	1.8e-07	0.92	0.37	0.57	FALSE
13	NAcc2	Srek1	intron excision ratio	chr2:34872488:34877765	0.06	0.07	top1	1	0.07	1.2e-04	-5.2	-5.2	1.9e-07	0.94	0.07	0.09	FALSE
14	NAcc2	Srek1	intron excision ratio	chr2:34872898:34877765	0.05	0.04	blup	1021	0.04	3.2e-03	-5.2	5.1	3.3e-07	-0.94	0.40	0.45	FALSE
15	OFC	Srek1	intron excision ratio	chr2:34872488:34877765	0.20	0.08	top1	1	0.09	4.9e-03	-5.1	-5.1	2.8e-07	0.94	0.06	0.06	FALSE
16	PL2	Nln	alternative polyA	ENSRNOT00000066925	0.05	0.02	top1	1	0.02	2.4e-02	-5.3	-5.3	1.5e-07	0.96	0.04	0.05	FALSE
17	PL2	Nln	alternative polyA	ENSRNOT00000082755	0.05	0.02	top1	1	0.02	2.5e-02	-5.3	5.3	1.5e-07	-0.96	0.04	0.05	FALSE
18	PL2	Nln	isoform ratio	ENSRNOT00000066925	0.05	0.02	top1	1	0.02	2.2e-02	-5.2	-5.2	1.6e-07	0.96	0.04	0.05	FALSE
19	PL2	Nln	isoform ratio	ENSRNOT00000082755	0.05	0.02	top1	1	0.02	2.5e-02	-5.2	5.2	1.6e-07	-0.96	0.04	0.05	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.