Best TWAS P=2.565298e-07 · Best GWAS P=8.045735e-08 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Ercc8 | alternative polyA | ENSRNOT00000013598 | 0.05 | 0.05 | top1 | 1 | 0.05 | 6.1e-06 | 5.2 | -5.2 | 2.6e-07 | -0.99 | 0.16 | 0.76 | TRUE |
| 2 | Adipose | Ercc8 | alternative polyA | ENSRNOT00000077938 | 0.04 | 0.04 | top1 | 1 | 0.04 | 1.3e-05 | 5.2 | 5.2 | 2.6e-07 | 0.99 | 0.13 | 0.56 | FALSE |
| 3 | Adipose | Ercc8 | alternative polyA | ENSRNOT00000013598 | 0.05 | 0.06 | top1 | 1 | 0.06 | 2.2e-07 | 5.2 | -5.2 | 2.6e-07 | -0.99 | 0.17 | 0.79 | FALSE |
| 4 | Adipose | Ercc8 | alternative polyA | ENSRNOT00000077938 | 0.05 | 0.06 | top1 | 1 | 0.06 | 1.9e-07 | 5.2 | 5.2 | 2.6e-07 | 0.99 | 0.17 | 0.80 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.