Hub : Traits : dissection: UMAP 3 of all traits : ← →

chr1:85,224,151-86,976,633

Best TWAS P=8.703605e-08 · Best GWAS P=1.543947e-07 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	BLA	Haus5	gene expression	ENSRNOG00000024266	0.31	0.26	lasso	28	0.27	1.1e-14	-5.0	-5.1	3.0e-07	0.88	0.32	0.68	FALSE
2	Brain	Fxyd5	gene expression	ENSRNOG00000021062	0.06	0.00	blup	1423	0.01	8.0e-02	-5.0	5.1	3.3e-07	-0.93	0.19	0.63	FALSE
3	Brain	Haus5	intron excision ratio	chr1:85913755:85915353	0.17	0.26	blup	1461	0.26	3.9e-24	-5.0	5.2	2.4e-07	-0.89	0.32	0.68	FALSE
4	Brain	Dmkn	intron excision ratio	chr1:86028416:86029802	0.07	0.03	enet	34	0.05	4.2e-05	-5.3	-5.4	8.7e-08	0.94	0.31	0.67	TRUE
5	NAcc2	Mag	intron excision ratio	chr1:86149948:86150252	0.09	0.05	top1	1	0.05	1.1e-03	-5.2	5.2	2.5e-07	-0.90	0.07	0.17	FALSE
6	NAcc2	Mag	intron excision ratio	chr1:86150348:86150856	0.07	0.03	blup	1550	0.03	6.6e-03	-5.1	-5.2	1.8e-07	0.94	0.24	0.65	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.