Hub : Traits : Retroperitoneal fat weight : ← : →

chr13:21,743,755-24,146,551

Trait: Retroperitoneal fat weight

Best TWAS P = 1.51e-10 · Best GWAS P= 5.39e-11 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Zcchc2	alternative polyA	XM_006249626.5	0.09	1732	0.02	2.8e-03	-5.8	6.49e-09	0.37	TRUE
Adipose	Zcchc2	alternative polyA	XM_006249626.5	0.11	1732	0.02	1.1e-03	-6.05	1.47e-09	0.54	FALSE
Adipose	LOC102550524	gene expression	LOC102550524	0.69	1731	0.25	9.1e-28	5.99	2.16e-09	0.77	FALSE
Adipose	Zcchc2	isoform ratio	NM_001122677.4	0.65	1732	0.19	2.0e-20	-5.39	7.19e-08	0.5	FALSE
Adipose	Zcchc2	isoform ratio	XM_006249626.5	0.6	224	0.21	1.9e-22	5.32	1.05e-07	0.5	TRUE
Adipose	Vps4b	mRNA stability	Vps4b	0.23	2520	0.07	3.7e-08	-5.22	1.82e-07	0.59	FALSE
BLA	Zcchc2	alternative polyA	NM_001271042.1	0.15	88	0.05	9.8e-04	5.22	1.83e-07	0.38	FALSE
BLA	Vps4b	gene expression	Vps4b	0.58	69	0.29	1.8e-15	-5.67	1.40e-08	0.56	FALSE
Brain	Zcchc2	alternative polyA	NM_001271042.1	0.08	1	0.02	2.3e-03	5.92	3.19e-09	0.04	FALSE
Brain	Zcchc2	alternative polyA	XM_006249626.5	0.06	1	0.01	1.6e-02	-5.8	6.60e-09	0.03	FALSE
Brain	Vps4b	mRNA stability	Vps4b	0.24	2520	0.12	3.5e-11	-5.87	4.41e-09	0.51	FALSE
IC	Vps4b	mRNA stability	Vps4b	0.18	1	0.04	1.3e-02	-6.1	1.05e-09	0.04	FALSE
IL	Vps4b	gene expression	Vps4b	0.72	32	0.24	1.8e-06	-5.68	1.38e-08	0.6	FALSE
LHb	Vps4b	mRNA stability	Vps4b	0.35	2520	0.11	1.3e-03	-5.98	2.22e-09	0.4	FALSE
Liver	Zcchc2	alternative polyA	XM_006249626.5	0.06	14	0	1.1e-01	-5.8	6.55e-09	0.26	FALSE
Liver	Zcchc2	intron excision ratio	chr13_22666438_22668143	0.06	1	0.02	3.2e-03	-5.82	5.99e-09	0.03	FALSE
Liver	Vps4b	mRNA stability	Vps4b	0.09	2520	0.03	1.5e-04	-5.71	1.13e-08	0.5	FALSE
NAcc	Zcchc2	alternative polyA	NM_001271042.1	0.08	1	0.02	3.9e-04	5.75	9.14e-09	0.04	FALSE
NAcc	Zcchc2	alternative polyA	NM_001271042.1	0.06	1	0.01	2.3e-02	5.79	7.13e-09	0.03	FALSE
NAcc	Bcl2	gene expression	Bcl2	0.24	10	0.11	1.0e-16	6.07	1.27e-09	0.76	FALSE
NAcc	LOC108352518	gene expression	LOC108352518	0.82	29	0.26	1.4e-39	5.94	2.79e-09	0.87	FALSE
NAcc	Zcchc2	isoform ratio	XM_063272225.1	0.04	1	0.01	2.5e-03	-5.92	3.24e-09	0.03	FALSE
NAcc	Bcl2	mRNA stability	Bcl2	0.16	1	0.02	7.8e-04	6.4	1.51e-10	0.23	TRUE
NAcc	Vps4b	mRNA stability	Vps4b	0.04	3	0	6.5e-02	-6.09	1.16e-09	0.2	FALSE
OFC	Vps4b	gene expression	Vps4b	0.66	1	0.31	3.6e-08	-5.8	6.56e-09	0.06	FALSE
PL	Vps4b	gene expression	Vps4b	0.53	89	0.34	1.2e-37	-5.6	2.09e-08	0.52	FALSE
PL	Zcchc2	gene expression	Zcchc2	0.17	27	0.08	8.6e-09	5.49	3.95e-08	0.49	FALSE
PL	Tnfrsf11a	mRNA stability	Tnfrsf11a	0.09	1	0.04	4.1e-05	-6.23	4.71e-10	0.52	TRUE
PL	Vps4b	mRNA stability	Vps4b	0.15	2520	0.04	9.2e-05	-5.38	7.33e-08	0.55	FALSE
pVTA	Bcl2	gene expression	Bcl2	0.08	2412	0.02	5.2e-03	-5.32	1.02e-07	0.16	FALSE
pVTA	Vps4b	mRNA stability	Vps4b	0.08	2520	0	1.6e-01	-5.61	1.98e-08	0.33	FALSE