Best TWAS P = 7.49e-09 · Best GWAS P= 8.32e-07 conditioned to 7.49e-01
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| LHb | Eif4a3 | mRNA stability | Eif4a3 | 0.32 | 718 | 0.15 | 1.7e-04 | -5.24 | 1.65e-07 | 0.45 | FALSE |
| NAcc | LOC108352165 | gene expression | LOC108352165 | 0.13 | 170 | 0.08 | 1.4e-11 | -5.27 | 1.38e-07 | 0.52 | FALSE |
| OFC | LOC108352165 | gene expression | LOC108352165 | 0.23 | 1893 | 0.04 | 3.5e-02 | -5.21 | 1.85e-07 | 0.26 | FALSE |
| pVTA | Slc26a11 | gene expression | Slc26a11 | 0.19 | 205 | 0.19 | 6.2e-15 | -5.78 | 7.49e-09 | 0.51 | TRUE |