chr1:134,466,988-135,864,494

Trait: Locomotion velocity, NPP test

Best TWAS P=1.91e-08 · Best GWAS P=2.10e-07 conditioned to 2.96e-74

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Brain Pde8a alternative polyA XM_006229438.4 0.17 21 0.19 1.2e-17 -5.19 2.15e-07 0.79 TRUE
Liver Pde8a alternative polyA XM_006229438.4 0.23 1855 0.18 4.2e-19 -5.19 2.05e-07 0.77 FALSE
PL Pde8a alternative polyA XM_006229438.4 0.06 10 0.04 8.1e-05 5.52 3.48e-08 0.55 FALSE
PL Pde8a alternative polyA XM_006229438.4 0.06 46 0.04 5.5e-05 5.62 1.91e-08 0.65 TRUE
PL Pde8a alternative polyA XM_006229439.4 0.05 1861 0.01 1.0e-02 5.22 1.80e-07 0.5 TRUE
PL Pde8a isoform ratio XM_006229438.4 0.05 58 0.03 5.4e-04 5.61 2.00e-08 0.69 FALSE