Hub : Traits : Extensor digitorum longus weight : ← : →

chr7:127,692,699-129,997,098

Trait: Extensor digitorum longus weight

Best TWAS P=7.54e-08 · Best GWAS P=1.12e-07 conditioned to 1.00e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Rpap3	mRNA stability	ENSRNOG00000053405	0.04	2213	0.03	2.7e-04	-5.1	3.35e-07	0.33	FALSE
Adipose	Hdac7	mRNA stability	ENSRNOG00000055597	0.18	238	0.17	5.4e-18	-5.37	7.85e-08	0.35	FALSE
BLA	Pced1b	alternative TSS	ENSRNOT00000009199	0.06	1	0.07	1.9e-04	5.18	2.26e-07	0.05	FALSE
BLA	Tmem106c	gene expression	ENSRNOG00000053269	0.24	22	0.3	1.3e-16	5.27	1.35e-07	0.39	FALSE
BLA	Rpap3	gene expression	ENSRNOG00000053405	0.57	156	0.39	3.7e-22	-5.18	2.28e-07	0.38	FALSE
BLA	Tmem106c	intron excision ratio	chr7:129089299:129091145	0.1	1	0.09	1.9e-05	-5.18	2.26e-07	0.1	FALSE
Brain	Slc48a1	gene expression	ENSRNOG00000053196	0.46	70	0.59	1.6e-67	5.14	2.77e-07	0.4	FALSE
Brain	Rpap3	gene expression	ENSRNOG00000053405	0.17	39	0.19	4.4e-17	-5.17	2.37e-07	0.38	FALSE
Brain	Tmem106c	intron excision ratio	chr7:129089299:129091145	0.12	1	0.04	1.9e-04	-5.18	2.20e-07	0.06	FALSE
Brain	Tmem106c	intron excision ratio	chr7:129091535:129091915	0.03	1	0.03	5.8e-04	5.18	2.20e-07	0.04	FALSE
IL	Slc48a1	gene expression	ENSRNOG00000053196	0.33	4	0.28	1.6e-07	5.12	3.00e-07	0.35	FALSE
LHb	Rapgef3	alternative TSS	ENSRNOT00000078644	0.35	1	0.25	1.1e-06	-5.19	2.10e-07	0.15	FALSE
LHb	Rapgef3	alternative TSS	ENSRNOT00000096691	0.53	2378	0.25	1.3e-06	5.14	2.78e-07	0.34	FALSE
LHb	Slc48a1	gene expression	ENSRNOG00000053196	0.57	2371	0.22	6.1e-06	5.38	7.54e-08	0.35	TRUE
LHb	Rapgef3	gene expression	ENSRNOG00000059961	0.33	2378	0.14	2.7e-04	5.25	1.56e-07	0.32	FALSE
LHb	Rapgef3	isoform ratio	ENSRNOT00000096691	0.17	73	0.16	1.5e-04	5.13	2.86e-07	0.32	TRUE
LHb	Rapgef3	intron excision ratio	chr7:128879272:128880061	0.14	14	0.13	7.1e-04	-5.19	2.09e-07	0.29	FALSE
Liver	Rpap3	gene expression	ENSRNOG00000053405	0.49	2213	0.45	2.6e-55	-5.14	2.78e-07	0.37	FALSE
Liver	Rpap3	mRNA stability	ENSRNOG00000053405	0.08	2213	0.06	1.5e-07	-5.1	3.32e-07	0.34	FALSE
Liver	Pfkm	mRNA stability	ENSRNOG00000057988	0.15	1	0.13	5.3e-14	-5.24	1.65e-07	0.64	FALSE
NAcc	Slc48a1	gene expression	ENSRNOG00000053196	0.39	2372	0.26	1.1e-19	5.19	2.13e-07	0.37	FALSE
NAcc	Tmem106c	gene expression	ENSRNOG00000053269	0.34	46	0.3	4.7e-23	5.17	2.32e-07	0.43	FALSE
OFC	Rapgef3	alternative TSS	ENSRNOT00000096691	0.2	2378	0.16	1.1e-04	5.13	2.82e-07	0.33	FALSE
OFC	Tmem106c	gene expression	ENSRNOG00000053269	0.22	1	0.18	4.7e-05	5.18	2.21e-07	0.1	FALSE
OFC	Rpap3	gene expression	ENSRNOG00000053405	0.31	2213	0.17	6.8e-05	-5.12	3.02e-07	0.34	FALSE
OFC	Hdac7	isoform ratio	ENSRNOT00000118593	0.12	1	0.15	1.7e-04	5.18	2.26e-07	0.05	FALSE
OFC	Tmem106c	intron excision ratio	chr7:129091964:129092334	0.33	1	0.12	8.8e-04	-5.19	2.14e-07	0.06	FALSE
PL	Rpap3	alternative TSS	ENSRNOT00000083926	0.05	2212	0.03	3.6e-03	5.11	3.30e-07	0.33	FALSE
PL	Rpap3	alternative TSS	ENSRNOT00000106326	0.05	2212	0.03	2.9e-03	-5.11	3.24e-07	0.34	FALSE
PL	Rpap3	alternative TSS	ENSRNOT00000083926	0.05	2212	0.03	4.5e-03	5.11	3.22e-07	0.33	FALSE
PL	Rpap3	alternative TSS	ENSRNOT00000106326	0.05	1	0.03	5.1e-03	-5.22	1.78e-07	0.04	FALSE
PL	Asb8	gene expression	ENSRNOG00000010099	0.03	1	0.02	9.5e-03	-5.18	2.26e-07	0.04	FALSE
PL	Slc48a1	gene expression	ENSRNOG00000053196	0.29	1	0.35	2.5e-27	5.18	2.21e-07	0.41	FALSE
PL	Tmem106c	gene expression	ENSRNOG00000053269	0.47	17	0.39	2.9e-31	5.18	2.17e-07	0.44	FALSE
PL	Rapgef3	isoform ratio	ENSRNOT00000096691	0.09	1	0.11	1.8e-08	5.18	2.26e-07	0.4	FALSE
PL	Tmem106c	intron excision ratio	chr7:129091535:129091915	0.11	1	0.09	1.3e-07	5.18	2.20e-07	0.45	FALSE
PL	Tmem106c	mRNA stability	ENSRNOG00000053269	0.11	1	0.12	1.4e-09	5.19	2.14e-07	0.49	FALSE