Best TWAS P=1.058985e-07 · Best GWAS P=3.963733e-08 conditioned to 0.1089936
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | OFC | Tenm4 | mRNA stability | ENSRNOG00000011151 | 0.24 | 0.2 | top1 | 1 | 0.2 | 1.7e-05 | -5.3 | 5.3 | 1.1e-07 | -0.9 | 0.14 | 0.08 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.