Hub : Traits : dissection: UMAP 1 of all traits : ← →

chr3:126,160,536-128,707,024

Best TWAS P=1.051345e-12 · Best GWAS P=1.331016e-13 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	AABR07054000.1	alternative polyA	ENSRNOT00000072928	0.26	0.13	blup	1836	0.16	2.6e-17	-5.7	6.2	7.3e-10	-0.94	0.44	0.56	FALSE
2	Adipose	AABR07054000.1	alternative polyA	ENSRNOT00000110455	0.08	0.06	lasso	22	0.06	5.7e-07	-5.7	-5.7	1.3e-08	0.94	0.43	0.57	FALSE
3	Adipose	AABR07054000.1	alternative polyA	ENSRNOT00000117007	0.07	0.04	top1	1	0.04	1.2e-05	-5.6	-5.6	2.4e-08	0.80	0.28	0.02	FALSE
4	Adipose	AABR07054000.1	gene expression	ENSRNOG00000050784	0.42	0.30	top1	1	0.30	4.0e-34	-6.0	-6.0	1.9e-09	0.96	0.97	0.03	FALSE
5	Adipose	AABR07054000.1	isoform ratio	ENSRNOT00000072928	0.28	0.15	lasso	59	0.19	8.1e-21	-5.5	5.9	4.0e-09	-0.91	0.62	0.38	FALSE
6	Adipose	AABR07054000.1	isoform ratio	ENSRNOT00000110455	0.09	0.06	blup	1836	0.06	1.8e-07	-7.0	-6.4	1.7e-10	0.95	0.44	0.56	FALSE
7	Adipose	AABR07054000.1	isoform ratio	ENSRNOT00000117007	0.15	0.08	enet	471	0.09	1.3e-10	-5.6	-5.9	4.2e-09	0.89	0.73	0.27	FALSE
8	Adipose	Esf1	mRNA stability	ENSRNOG00000004777	0.17	0.06	blup	1671	0.07	2.9e-08	4.8	-5.7	9.5e-09	0.58	1.00	0.00	FALSE
9	Adipose	Ndufaf5	mRNA stability	ENSRNOG00000004784	0.04	0.00	enet	54	0.01	1.5e-02	-5.5	-5.8	5.4e-09	0.84	0.41	0.52	FALSE
10	BLA	AABR07054000.1	alternative polyA	ENSRNOT00000072928	0.14	0.08	blup	1836	0.09	1.9e-05	-6.2	6.7	1.9e-11	-0.92	0.48	0.52	FALSE
11	BLA	AABR07054000.1	alternative polyA	ENSRNOT00000117007	0.12	0.08	top1	1	0.08	7.2e-05	-5.8	-5.8	6.0e-09	0.90	0.10	0.04	FALSE
12	BLA	Flrt3	gene expression	ENSRNOG00000004874	0.06	0.04	top1	1	0.04	5.4e-03	-5.5	5.5	3.1e-08	-0.66	0.08	0.04	FALSE
13	BLA	AABR07054000.1	gene expression	ENSRNOG00000050784	0.09	0.02	enet	49	0.03	1.5e-02	-5.6	7.0	1.9e-12	-0.79	0.67	0.18	FALSE
14	BLA	AABR07054000.1	isoform ratio	ENSRNOT00000072928	0.15	0.14	blup	1836	0.15	2.4e-08	-6.2	6.6	4.5e-11	-0.94	0.69	0.31	FALSE
15	BLA	AABR07054000.1	isoform ratio	ENSRNOT00000117007	0.11	0.07	top1	1	0.07	1.1e-04	-5.8	-5.8	6.0e-09	0.93	0.17	0.04	FALSE
16	BLA	Ndufaf5	intron excision ratio	chr3:127508215:127509498	0.80	0.43	enet	162	0.44	6.0e-26	4.8	-5.6	1.7e-08	0.79	1.00	0.00	FALSE
17	BLA	Ndufaf5	intron excision ratio	chr3:127508256:127509498	0.79	0.43	enet	169	0.44	7.1e-26	4.8	5.6	2.2e-08	-0.78	1.00	0.00	FALSE
18	BLA	AABR07054000.1	intron excision ratio	chr3:127725722:127747858	0.07	0.01	blup	1836	0.01	5.4e-02	-6.6	5.1	2.9e-07	-0.85	0.48	0.27	FALSE
19	BLA	AABR07054000.1	intron excision ratio	chr3:127725722:127779334	0.06	0.03	top1	1	0.03	1.6e-02	-6.6	-6.6	3.2e-11	0.95	0.07	0.04	FALSE
20	BLA	Tasp1	mRNA stability	ENSRNOG00000004493	0.11	0.08	lasso	5	0.08	2.9e-05	-5.7	5.7	1.5e-08	-0.94	0.44	0.54	TRUE
21	Brain	AABR07054000.1	alternative polyA	ENSRNOT00000072928	0.03	0.02	top1	1	0.02	4.5e-03	-5.8	5.8	5.1e-09	-0.97	0.06	0.03	FALSE
22	Brain	Sptlc3	gene expression	ENSRNOG00000004443	0.06	0.03	lasso	5	0.05	1.0e-05	4.7	5.3	1.3e-07	-0.32	0.63	0.36	TRUE
23	Brain	Esf1	gene expression	ENSRNOG00000004777	0.69	0.52	enet	101	0.53	7.6e-58	5.1	5.2	1.7e-07	-0.51	1.00	0.00	TRUE
24	Brain	AABR07054000.1	gene expression	ENSRNOG00000050784	0.04	0.05	top1	1	0.05	2.2e-05	-6.7	6.7	2.0e-11	-0.84	0.12	0.18	FALSE
25	Brain	Ism1	gene expression	ENSRNOG00000063262	0.05	0.03	enet	32	0.04	8.7e-05	-5.4	5.8	7.1e-09	-0.89	0.47	0.52	FALSE
26	Brain	AABR07054000.1	isoform ratio	ENSRNOT00000072928	0.04	0.04	top1	1	0.04	6.8e-05	-6.0	6.0	2.7e-09	-0.96	0.30	0.03	FALSE
27	Brain	AABR07054000.1	isoform ratio	ENSRNOT00000117007	0.04	0.02	top1	1	0.02	3.2e-03	-5.7	-5.7	1.5e-08	0.97	0.07	0.03	FALSE
28	Brain	Tasp1	mRNA stability	ENSRNOG00000004493	0.13	0.14	lasso	26	0.14	7.5e-13	-5.2	5.2	2.0e-07	-0.93	0.65	0.35	FALSE
29	Eye	Ism1	gene expression	ENSRNOG00000063262	0.59	0.02	blup	1704	0.07	3.4e-02	-5.7	-5.9	3.4e-09	0.88	0.22	0.23	FALSE
30	IL	AABR07054000.1	gene expression	ENSRNOG00000050784	0.21	0.05	top1	1	0.04	3.1e-02	-6.4	6.4	1.1e-10	-0.95	0.09	0.05	FALSE
31	IL	AABR07054000.1	isoform ratio	ENSRNOT00000117007	0.18	0.11	top1	1	0.11	1.2e-03	-6.0	-6.0	1.7e-09	0.88	0.10	0.05	FALSE
32	IL	Tasp1	intron excision ratio	chr3:127355890:127385049	0.25	0.01	enet	9	0.06	1.6e-02	4.6	5.4	5.7e-08	-0.56	0.43	0.07	FALSE
33	IL	Tasp1	mRNA stability	ENSRNOG00000004493	0.14	0.07	blup	1685	0.10	2.2e-03	-5.7	6.0	1.8e-09	-0.93	0.39	0.40	FALSE
34	IL	Ndufaf5	mRNA stability	ENSRNOG00000004784	0.19	0.08	top1	1	0.08	6.8e-03	-6.2	-6.2	4.4e-10	0.96	0.09	0.07	FALSE
35	LHb	AABR07054000.1	gene expression	ENSRNOG00000050784	0.23	0.15	enet	97	0.17	9.3e-05	-5.9	6.1	8.0e-10	-0.97	0.30	0.67	FALSE
36	LHb	AABR07054000.1	intron excision ratio	chr3:127725722:127747858	0.14	0.05	top1	1	0.05	2.9e-02	-6.0	6.0	2.4e-09	-0.76	0.09	0.05	FALSE
37	LHb	AABR07054000.1	intron excision ratio	chr3:127725722:127779334	0.13	0.03	top1	1	0.03	6.5e-02	-6.0	-6.0	2.4e-09	0.76	0.09	0.05	FALSE
38	Liver	Flrt3	alternative TSS	ENSRNOT00000006454	0.03	0.01	blup	2101	0.01	2.0e-02	-5.9	-6.7	1.8e-11	0.95	0.44	0.20	FALSE
39	Liver	Flrt3	isoform ratio	ENSRNOT00000006454	0.03	0.01	blup	2101	0.01	6.6e-02	-5.9	-6.7	2.4e-11	0.96	0.40	0.18	FALSE
40	Liver	AABR07054000.1	intron excision ratio	chr3:127747955:127748961	0.03	0.01	blup	1836	0.01	1.4e-02	-7.0	5.8	5.0e-09	-0.90	0.32	0.40	FALSE
41	Liver	AABR07054000.1	intron excision ratio	chr3:127747955:127749007	0.03	0.01	enet	25	0.02	5.2e-03	-5.7	-7.1	1.1e-12	0.87	0.36	0.46	TRUE
42	NAcc	AABR07054000.1	alternative polyA	ENSRNOT00000072928	0.20	0.17	top1	1	0.17	1.1e-04	-5.7	5.7	1.6e-08	-0.94	0.11	0.05	FALSE
43	NAcc	AABR07054000.1	alternative TSS	ENSRNOT00000074338	0.11	0.10	blup	1834	0.10	2.5e-03	-7.0	6.3	2.7e-10	-0.90	0.37	0.36	TRUE
44	NAcc	AABR07054000.1	gene expression	ENSRNOG00000050784	0.35	0.28	top1	1	0.28	5.7e-07	-6.1	6.1	1.4e-09	-0.92	0.20	0.05	FALSE
45	NAcc	AABR07054000.1	isoform ratio	ENSRNOT00000072928	0.14	0.15	lasso	2	0.15	3.3e-04	-5.7	5.8	4.9e-09	-0.96	0.52	0.27	FALSE
46	NAcc2	AABR07054000.1	alternative polyA	ENSRNOT00000072928	0.19	0.02	blup	1836	0.06	2.7e-04	5.0	6.4	1.6e-10	-0.83	0.75	0.16	FALSE
47	NAcc2	Tasp1	gene expression	ENSRNOG00000004493	0.08	0.03	lasso	15	0.05	1.7e-03	-5.7	-5.7	1.4e-08	0.95	0.51	0.44	FALSE
48	NAcc2	AABR07054000.1	gene expression	ENSRNOG00000050784	0.10	0.08	blup	1836	0.08	3.0e-05	-5.6	6.1	1.2e-09	-0.93	0.56	0.42	FALSE
49	NAcc2	AABR07054000.1	isoform ratio	ENSRNOT00000072928	0.18	0.03	enet	38	0.08	3.3e-05	-5.7	7.1	1.2e-12	-0.83	0.68	0.28	FALSE
50	NAcc2	AABR07054000.1	isoform ratio	ENSRNOT00000117007	0.15	0.10	top1	1	0.10	6.0e-06	-6.2	-6.2	4.1e-10	0.96	0.42	0.07	FALSE
51	NAcc2	Tasp1	intron excision ratio	chr3:127385117:127399392	0.06	0.01	blup	1687	0.04	5.0e-03	-5.7	6.5	6.6e-11	-0.88	0.35	0.47	FALSE
52	NAcc2	Ndufaf5	intron excision ratio	chr3:127508215:127509498	0.60	0.40	blup	1671	0.41	7.2e-24	4.8	-5.3	9.4e-08	0.57	1.00	0.00	FALSE
53	NAcc2	Ndufaf5	intron excision ratio	chr3:127508256:127509498	0.60	0.39	blup	1671	0.41	2.0e-23	4.8	5.3	9.0e-08	-0.56	1.00	0.00	FALSE
54	NAcc2	Ndufaf5	mRNA stability	ENSRNOG00000004784	0.09	0.02	blup	1671	0.05	9.0e-04	-5.7	-6.0	2.0e-09	0.83	0.42	0.45	FALSE
55	OFC	AABR07054000.1	alternative polyA	ENSRNOT00000072928	0.21	0.10	top1	1	0.10	2.4e-03	-5.9	5.9	2.9e-09	-0.95	0.09	0.05	FALSE
56	OFC	Ism1	gene expression	ENSRNOG00000063262	0.24	0.12	top1	1	0.12	1.1e-03	-5.7	5.7	1.4e-08	-0.94	0.09	0.07	FALSE
57	OFC	Ndufaf5	intron excision ratio	chr3:127508256:127509498	0.61	0.21	blup	1669	0.24	1.6e-06	4.8	5.1	2.8e-07	-0.47	0.97	0.01	FALSE
58	OFC	Tasp1	mRNA stability	ENSRNOG00000004493	0.17	0.11	top1	1	0.11	1.2e-03	-6.1	6.1	1.4e-09	-0.95	0.09	0.06	FALSE
59	PL	AABR07054000.1	alternative polyA	ENSRNOT00000072928	0.14	0.06	top1	1	0.06	1.6e-02	-6.7	6.7	2.4e-11	-0.97	0.09	0.05	FALSE
60	PL2	AABR07054000.1	alternative polyA	ENSRNOT00000072928	0.17	0.15	top1	1	0.15	1.8e-08	-6.1	6.1	1.1e-09	-0.96	0.95	0.04	FALSE
61	PL2	AABR07054000.1	alternative polyA	ENSRNOT00000117007	0.18	0.12	top1	1	0.12	4.7e-07	-6.2	-6.2	5.2e-10	0.95	0.88	0.08	FALSE
62	PL2	AABR07054000.1	gene expression	ENSRNOG00000050784	0.13	0.12	blup	1836	0.14	7.5e-08	-5.8	6.0	2.2e-09	-0.87	0.75	0.24	FALSE
63	PL2	AABR07054000.1	isoform ratio	ENSRNOT00000072928	0.18	0.15	blup	1836	0.16	4.2e-09	-5.6	6.6	3.1e-11	-0.95	0.76	0.24	FALSE
64	PL2	AABR07054000.1	isoform ratio	ENSRNOT00000117007	0.12	0.11	top1	1	0.11	1.9e-06	-6.2	-6.2	4.1e-10	0.97	0.69	0.09	FALSE
65	PL2	AABR07054000.1	intron excision ratio	chr3:127725722:127747858	0.07	0.04	top1	1	0.04	2.0e-03	-5.5	5.5	3.1e-08	-0.90	0.08	0.04	FALSE
66	PL2	AABR07054000.1	intron excision ratio	chr3:127725722:127779334	0.08	0.05	top1	1	0.05	1.4e-03	-5.8	-5.8	6.2e-09	0.90	0.08	0.04	FALSE
67	PL2	Tasp1	mRNA stability	ENSRNOG00000004493	0.06	0.05	top1	1	0.05	6.9e-04	-5.7	5.7	1.3e-08	-0.95	0.08	0.04	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.