Hub : Traits : Retroperitoneal fat weight : ← : →

chr3:126,160,536-128,707,024

Trait: Retroperitoneal fat weight

Best TWAS P=1.37e-10 · Best GWAS P=4.41e-12 conditioned to 2.87e-32

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h2	# weights	Model R2	Model R2 P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Macrod2	alternative TSS	XM_039106857.1	0.1	84	0.06	3.0e-07	5.35	8.66e-08	0.54	FALSE
Adipose	Macrod2	alternative TSS	XM_039106861.1	0.12	1	0.08	7.9e-09	-5.2	2.03e-07	0.06	FALSE
Adipose	Tasp1	alternative TSS	XM_039105024.1	0.03	4	0.02	1.6e-03	5.86	4.63e-09	0.43	TRUE
Adipose	Tasp1	alternative TSS	XM_039105025.1	0.06	1686	0.05	1.8e-06	5.86	4.55e-09	0.51	FALSE
Adipose	Tasp1	alternative TSS	XM_039105026.1	0.04	1686	0.02	1.3e-03	-5.92	3.29e-09	0.42	FALSE
Adipose	Tasp1	alternative TSS	XM_039105024.1	0.03	39	0.01	7.6e-03	5.75	9.18e-09	0.35	TRUE
Adipose	Tasp1	alternative TSS	XM_039105025.1	0.07	1686	0.06	5.2e-07	5.86	4.53e-09	0.52	FALSE
Adipose	Tasp1	alternative TSS	XM_039105026.1	0.03	1686	0.01	1.6e-02	-5.91	3.34e-09	0.32	FALSE
Adipose	Macrod2	gene expression	Macrod2	0.49	1	0.35	3.7e-40	-6.1	1.08e-09	0.9	FALSE
Adipose	Macrod2	mRNA stability	Macrod2	0.44	457	0.29	2.0e-32	-5.89	3.97e-09	0.41	FALSE
Adipose	Ndufaf5	mRNA stability	Ndufaf5	0.04	1668	0.03	5.7e-04	5.38	7.49e-08	0.48	FALSE
BLA	Macrod2	gene expression	Macrod2	0.12	29	0.08	5.5e-05	5.7	1.21e-08	0.47	FALSE
BLA	Macrod2	intron excision ratio	chr3_127725722_127779334	0.06	1	0.03	1.5e-02	-5.63	1.83e-08	0.04	FALSE
BLA	Macrod2	mRNA stability	Macrod2	0.14	1	0.09	1.6e-05	-5.62	1.87e-08	0.18	FALSE
BLA	Tasp1	mRNA stability	Tasp1	0.08	1	0.07	1.5e-04	5.29	1.24e-07	0.06	FALSE
Brain	Ism1	gene expression	Ism1	0.11	1710	0.12	3.7e-11	-5.21	1.90e-07	0.58	FALSE
Brain	LOC102548513	gene expression	LOC102548513	0.04	2054	0.03	4.6e-04	-6.09	1.14e-09	0.26	FALSE
Brain	Sptlc3	gene expression	Sptlc3	0.06	1712	0.03	4.9e-04	-5.44	5.27e-08	0.5	FALSE
IL	LOC102548513	gene expression	LOC102548513	0.33	2054	0.17	5.5e-05	-5.59	2.31e-08	0.26	FALSE
IL	Tasp1	mRNA stability	Tasp1	0.11	1687	0.05	2.8e-02	-5.35	9.00e-08	0.36	FALSE
LHb	LOC102548513	gene expression	LOC102548513	0.17	1	0.16	1.1e-04	5.28	1.32e-07	0.05	FALSE
Liver	Flrt3	gene expression	Flrt3	0.08	1	0.01	9.0e-03	5.19	2.11e-07	0.03	TRUE
Liver	Esf1	isoform ratio	XM_006235105.4	0.15	1668	0.07	1.3e-08	-5.27	1.33e-07	0.01	TRUE
NAcc	Ndufaf5	gene expression	Ndufaf5	0.02	1669	0	9.7e-02	5.91	3.48e-09	0.37	FALSE
NAcc	Tasp1	isoform ratio	XM_039105026.1	0.03	31	0.03	8.0e-05	5.52	3.42e-08	0.48	FALSE
NAcc	Macrod2	intron excision ratio	chr3_127725722_127747858	0.05	8	0.03	4.5e-04	-6.42	1.37e-10	0.54	TRUE
NAcc	Macrod2	intron excision ratio	chr3_127725722_127779334	0.05	8	0.03	5.0e-04	6.36	2.06e-10	0.52	FALSE
NAcc	Tasp1	intron excision ratio	chr3_127385117_127399392	0.04	1687	0.04	1.2e-05	-5.83	5.61e-09	0.52	FALSE
OFC	Tasp1	mRNA stability	Tasp1	0.21	12	0.1	2.5e-03	5.19	2.08e-07	0.42	FALSE
PL	Ism1	gene expression	Ism1	0.02	1	0.02	5.5e-03	5.29	1.24e-07	0.06	FALSE
PL	Macrod2	gene expression	Macrod2	0.05	1	0.05	2.1e-06	-5.23	1.68e-07	0.06	FALSE
PL	Ndufaf5	gene expression	Ndufaf5	0.04	1669	0.02	4.7e-03	5.96	2.56e-09	0.47	FALSE
PL	Ndufaf5	isoform ratio	XM_039104593.1	0.26	56	0.19	4.2e-20	5.26	1.43e-07	0.01	FALSE
PL	Tasp1	isoform ratio	XM_039105026.1	0.04	1	0.05	8.5e-06	5.32	1.04e-07	0.38	FALSE
PL	Macrod2	intron excision ratio	chr3_127725722_127747858	0.06	1830	0.08	5.8e-09	-5.77	7.73e-09	0.12	FALSE
PL	Macrod2	intron excision ratio	chr3_127725722_127779334	0.06	1830	0.08	5.3e-09	5.77	7.72e-09	0.12	FALSE
PL	Macrod2	mRNA stability	Macrod2	0.07	1	0.09	2.0e-10	-5.62	1.87e-08	0.37	FALSE
PL	Ndufaf5	mRNA stability	Ndufaf5	0.13	31	0.11	1.3e-11	-5.37	8.05e-08	0.09	FALSE
pVTA	Flrt3	gene expression	Flrt3	0.1	1	0.09	7.1e-05	6.24	4.33e-10	0.05	FALSE