Best TWAS P=4.418192e-12 · Best GWAS P=0.005203634 conditioned to 0.0002458686
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Apeh | mRNA stability | ENSRNOG00000029572 | 0.18 | 0.03 | enet | 335 | 0.04 | 0.00042 | 2.3 | -6.9 | 4.4e-12 | -0.75 | 0.06 | 0.15 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.