Best TWAS P=3.458449e-07 · Best GWAS P=0.007764558 conditioned to 0.3426175
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | Zfp14 | gene expression | ENSRNOG00000030932 | 0.17 | 0.02 | enet | 376 | 0.03 | 0.00027 | -2.5 | -5.1 | 3.5e-07 | -0.66 | 0.09 | 0.09 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.