Best TWAS P=1.19833e-07 · Best GWAS P=3.282327e-07 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | OFC | Afap1l2 | mRNA stability | ENSRNOG00000017164 | 0.55 | 0.16 | enet | 14 | 0.33 | 1.3e-08 | 4.9 | -5.3 | 1.2e-07 | -0.95 | 0.43 | 0.57 | TRUE |
| 2 | OFC | Dclre1a | mRNA stability | ENSRNOG00000026204 | 0.34 | 0.22 | enet | 11 | 0.29 | 1.1e-07 | 4.9 | 5.1 | 3.3e-07 | 0.88 | 0.44 | 0.55 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.