Best TWAS P=6.007703e-08 · Best GWAS P=6.25888e-06 conditioned to 0.0117515
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | Tmod1 | alternative polyA | ENSRNOT00000013228 | 0.17 | 0.04 | blup | 1813 | 0.04 | 1.9e-05 | 4.3 | 5.4 | 6.0e-08 | 0.41 | 0.06 | 0.88 | TRUE |
2 | Liver | Tmod1 | alternative polyA | ENSRNOT00000109364 | 0.19 | 0.03 | blup | 1813 | 0.04 | 1.5e-05 | 4.3 | -5.3 | 1.1e-07 | -0.34 | 0.06 | 0.86 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.