Best TWAS P=2.616321e-07 · Best GWAS P=6.895393e-10 conditioned to 0.000444029
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Wnt5a | gene expression | ENSRNOG00000015618 | 0.03 | 0.01 | lasso | 22 | 0.01 | 0.009 | 4.7 | 5.1 | 2.6e-07 | -0.9 | 0.3 | 0.49 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.